An NIR fluorescent/photoacoustic dual-mode probe of NADPH for tumor imaging

A novel probe was synthesized with a turn-on NIR fluorescent (NIRF)/photoacoustic (PA) response to NADPH, which was successfully applied in both monitoring intracellular NADPH and dual-modal imaging of tumor-bearing mice. It exhibits good potential in studying and understanding the tumor energy metabolism and treatment process related to NADPH.

Automated summary

A novel probe with a turn-on NIR fluorescent/photoacoustic response to NADPH was successfully used for monitoring intracellular NADPH and dual-modal imaging of tumor-bearing mice. It shows great potential in studying and understanding tumor energy metabolism and treatment process related to NADPH.