☆ 4.7 Review

The impact of triglyceride-glucose index on ischemic stroke: a systematic review and meta-analysis

CARDIOVASCULAR DIABETOLOGY (2023)

Related references

Note: Only part of the references are listed.

Article Cardiac & Cardiovascular Systems

Cumulative triglyceride-glucose index is a risk for CVD: a prospective cohort study

Haozhe Cui et al.

Summary: The study found that cumulative TyG index is associated with an increased risk of cardiovascular disease. Long-term exposure to higher TyG index is significantly associated with an increased risk of cardiovascular disease in the population.

CARDIOVASCULAR DIABETOLOGY (2022)

Add to Collection

Article Cardiac & Cardiovascular Systems

Evaluation of the long-term prognostic ability of triglyceride-glucose index for elderly acute coronary syndrome patients: a cohort study

Yang Jiao et al.

Summary: The study found that the TyG index is a strong predictor of adverse events in elderly patients with ACS, serving as an independent predictor for long-term prognosis.

CARDIOVASCULAR DIABETOLOGY (2022)

Add to Collection

Article Multidisciplinary Sciences

Association of triglyceride-glucose index with clinical outcomes in patients with acute ischemic stroke receiving intravenous thrombolysis

Emma M. S. Toh et al.

Summary: This study found that the TyG index, a measure of insulin resistance, is significantly associated with poorer clinical outcomes in patients with acute ischemic stroke who received tPA, including higher 90-day mortality rate, worse functional outcomes, and lack of early neurological improvement.

SCIENTIFIC REPORTS (2022)

Add to Collection

Article Clinical Neurology

Triglyceride-Glucose Index and Intravenous Thrombolysis Outcomes for Acute Ischemic Stroke: A Multicenter Prospective-Cohort Study

Sheng-Feng Lin et al.

Summary: This study demonstrates a strong association between an increased TyG index and increased unfavorable functional outcomes at 90 days in patients with acute ischemic stroke treated with IVT. This association was found to be robust in patients with moderate and high stroke severity.

FRONTIERS IN NEUROLOGY (2022)

Add to Collection

Article Medicine, General & Internal

Relationship Between the Triglyceride Glucose Index and the Risk of First Stroke in Elderly Hypertensive Patients

Longlong Hu et al.

Summary: This study found a positive association between the TyG index and the risk of first stroke and first ischemic stroke in elderly individuals with hypertension.

INTERNATIONAL JOURNAL OF GENERAL MEDICINE (2022)

Add to Collection

Article Cardiac & Cardiovascular Systems

Distinct triglyceride-glucose trajectories are associated with different risks of incident cardiovascular disease in normal-weight adults

Xue Tian et al.

Summary: This study identified five distinct trajectories of TyG index in normal-weight adults and found that these trajectories were differently associated with the risk of cardiovascular disease. The high-stable pattern showed the highest risk of CVD.

AMERICAN HEART JOURNAL (2022)

Add to Collection

Article Clinical Neurology

Association of triglyceride-glucose index and stroke recurrence among nondiabetic patients with acute ischemic stroke

Xiaomeng Yang et al.

Summary: The study found that elevated TyG index is associated with an increased risk of stroke recurrence and death. However, neither TyG nor HOMA-IR can be qualified predictors of stroke recurrence and death in nondiabetic acute ischemic stroke patients.

BMC NEUROLOGY (2022)

Add to Collection

Article Cardiac & Cardiovascular Systems

Relationship of cumulative exposure to the triglyceride-glucose index with ischemic stroke: a 9-year prospective study in the Kailuan cohort

Xianxuan Wang et al.

Summary: This study evaluated the association between cumulative TyG index exposure and the risk of ischemic stroke, and found that a high cumulative TyG index is associated with a higher risk of ischemic stroke.

CARDIOVASCULAR DIABETOLOGY (2022)

Add to Collection

Review Endocrinology & Metabolism

Triglyceride-Glucose Index and the Risk of Stroke: A Systematic Review and Dose-Response Meta-Analysis

Xiao Feng et al.

Summary: The TyG index is non-linearly associated with stroke, and a higher TyG index is an independent risk factor for incident strokes, especially ischemic stroke.

HORMONE AND METABOLIC RESEARCH (2022)

Add to Collection

Article Cardiac & Cardiovascular Systems

Triglyceride-glucose index trajectory and stroke incidence in patients with hypertension: a prospective cohort study

Zegui Huang et al.

Summary: This study investigated the association between TyG index trajectory and stroke risk among hypertensive patients. The findings suggest that a long-term elevated TyG index is associated with an increased risk of stroke, especially ischemic stroke, in hypertensive patients.

CARDIOVASCULAR DIABETOLOGY (2022)

Add to Collection

Article Endocrinology & Metabolism

Triglyceride-glucose index and stroke recurrence in elderly patients with ischemic stroke

Fang Wang et al.

Summary: This study found an association between triglyceride-glucose index and stroke recurrence in elderly patients with ischemic stroke in China. The triglyceride-glucose index could serve as a predictive marker for stroke recurrence.

FRONTIERS IN ENDOCRINOLOGY (2022)

Add to Collection

Article Endocrinology & Metabolism

Triglyceride-glucose index associated with the risk of cardiovascular disease: the Kailuan study

Qian Liu et al.

Summary: The study found that the TyG index is positively correlated with the risk of CVD in a Chinese population, indicating its independent predictive value. This may aid in identifying individuals at higher risk of cardiovascular diseases early on, and could be useful for primary prevention strategies.

ENDOCRINE (2022)

Add to Collection

Article Cardiac & Cardiovascular Systems

Platelet Endothelial Aggregation Receptor 1 Polymorphism Is Associated With Functional Outcome in Small-Artery Occlusion Stroke Patients Treated With Aspirin

Zhizhang Li et al.

Summary: The study showed that the PEAR1 rs12041331 polymorphism is associated with outcomes in acute ischemic stroke patients treated with aspirin, especially in patients with the SAO subtype. The AA genotype of PEAR1 may be a sensitive factor for favorable functional outcomes in SAO patients treated with aspirin alone.

FRONTIERS IN CARDIOVASCULAR MEDICINE (2021)

Add to Collection

Review Cardiac & Cardiovascular Systems

The multifaceted contribution of platelets in the emergence and aftermath of acute cardiovascular events

Danielle M. Coenen et al.

Summary: Atherosclerosis is a major contributor to various cardiovascular diseases, characterized by plaques and arterial wall thickening. Platelets play a crucial role in both the later stages of atherosclerosis, such as thrombotic occlusion, and in the earlier stages by exhibiting pro-inflammatory activities.

ATHEROSCLEROSIS (2021)

Add to Collection

Article Cardiac & Cardiovascular Systems

Triglyceride-glucose index is associated with the risk of myocardial infarction: an 11-year prospective study in the Kailuan cohort

Xue Tian et al.

Summary: The study found that elevated levels of baseline and long-term TyG index are associated with an increased risk of myocardial infarction, with a stronger association in women. This suggests that the TyG index may be useful for identifying individuals at high risk of developing MI.

CARDIOVASCULAR DIABETOLOGY (2021)

Add to Collection

Review Cardiac & Cardiovascular Systems

Association of premature ventricular complexes and risk of ischemic stroke: A systematic review and meta-analysis

Pongprueth Rujirachun et al.

Summary: Recent studies suggest that patients with premature ventricular complexes (PVCs) may have a higher risk of ischemic stroke. A systematic review and meta-analysis found that PVCs are associated with a higher risk of ischemic stroke, but further research is needed to determine causality and clinical implications.

CLINICAL CARDIOLOGY (2021)

Add to Collection

Article Clinical Neurology

Triglyceride glucose index influences platelet reactivity in acute ischemic stroke patients

Yinping Guo et al.

Summary: In acute ischemic stroke patients taking dual antiplatelet therapy, the elevation of the TyG index is associated with enhanced platelet reactivity and a higher prevalence of aspirin high residual platelet reactivity. Insulin resistance assessed by the TyG index could be an independent risk factor for aspirin high residual platelet reactivity.

BMC NEUROLOGY (2021)

Add to Collection

Article Clinical Neurology

Triglyceride-glucose index is associated with early neurological deterioration in single subcortical infarction: Early prognosis in single subcortical infarctions

Ki-Woong Nam et al.

Summary: The triglyceride-glucose index was found to be associated with early neurological deterioration in patients with single subcortical infarctions, with this association being influenced by the location of the lesion and the presence of untreated diabetes.

INTERNATIONAL JOURNAL OF STROKE (2021)

Add to Collection

Article Peripheral Vascular Disease

Triglyceride-Glucose Index as a Surrogate Marker of Insulin Resistance for Predicting Cardiovascular Outcomes in Nondiabetic Patients with Non-ST-Segment Elevation Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention

Qi Zhao et al.

Summary: The triglyceride-glucose index (TyG index) is an independent risk predictor for adverse cardiovascular events in nondiabetic subjects diagnosed with NSTE-ACS who received elective PCI. Further prospective studies are needed to verify these findings.

JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS (2021)

Add to Collection

Article Cardiac & Cardiovascular Systems

Causal Effect of the Triglyceride-Glucose Index and the Joint Exposure of Higher Glucose and Triglyceride With Extensive Cardio-Cerebrovascular Metabolic Outcomes in the UK Biobank: A Mendelian Randomization Study

Shucheng Si et al.

Summary: The TyG index was significantly associated with cardiovascular diseases risk, while the joint exposure to higher glucose and triglyceride was significantly associated with overall cardiovascular diseases and ischemic heart disease risk, but not with cerebrovascular disease risk. The genetic effects of glucose and triglyceride were independent of each other and showed dose-response effects.

FRONTIERS IN CARDIOVASCULAR MEDICINE (2021)

Add to Collection

Article Cardiac & Cardiovascular Systems

Triglyceride-glucose index and the risk of stroke and its subtypes in the general population: an 11-year follow-up

Anxin Wang et al.

Summary: Elevated levels of both baseline and long-term updated cumulative average TyG index can independently predict stroke and ischemic stroke but not intracerebral hemorrhage in the general population during an 11-year follow-up. The study found a linear association between TyG index and stroke outcomes, with higher TyG index associated with increased risk of stroke.

CARDIOVASCULAR DIABETOLOGY (2021)

Add to Collection

Article Endocrinology & Metabolism

Elevated triglyceride-glucose index predicts risk of incident ischaemic stroke: The Rural Chinese cohort study

Yang Zhao et al.

Summary: This study aimed to investigate the association between triglyceride-glucose (TyG) and incident ischemic stroke, as well as assess the potential modification effect by known risk factors of stroke. The results showed that elevated TyG index is an independent predictor of ischemic stroke in the general population, and insulin resistance may be positively associated with future stroke risk.

DIABETES & METABOLISM (2021)

Add to Collection

Article Medicine, General & Internal

Ticagrelor versus Clopidogrel in CYP2C19 Loss-of-Function Carriers with Stroke or TIA

Yongjun Wang et al.

Summary: This study compared ticagrelor and clopidogrel for the secondary prevention of stroke in Chinese patients with minor ischemic stroke or TIA who carried CYP2C19 loss-of-function alleles. The results showed that ticagrelor was associated with a modestly lower risk of stroke at 90 days compared to clopidogrel, with no difference in severe or moderate bleeding risk between the two treatment groups.

NEW ENGLAND JOURNAL OF MEDICINE (2021)

Add to Collection

Review Biochemistry & Molecular Biology

The Blood-Brain Barrier, Oxidative Stress, and Insulin Resistance

William A. Banks et al.

Summary: The blood-brain barrier serves as a crucial interface between the periphery and the central nervous system, protecting the CNS from oxidative stress. The impact of oxidative stress on brain endothelial cells can disrupt insulin signaling, leading to disease development in conditions like diabetes mellitus and Alzheimer's disease.

ANTIOXIDANTS (2021)

Add to Collection

Article Multidisciplinary Sciences

Comparison of the triglyceride glucose index and blood leukocyte indices as predictors of metabolic syndrome in healthy Chinese population

Hai-Yan Lin et al.

Summary: The study revealed that in the Chinese population, the TyG index and neutrophils may be predictors of metabolic syndrome development, while total leukocytes, lymphocytes, and neutrophil-to-lymphocyte ratio were not significantly associated with incident MetS.

SCIENTIFIC REPORTS (2021)

Add to Collection

Review Medicine, General & Internal

The PRISMA 2020 statement: an updated guideline for reporting systematic reviews

Matthew J. Page et al.

Summary: The PRISMA statement was designed to help systematic reviewers transparently report the purpose, methods, and findings of their reviews. The updated PRISMA 2020 statement includes new reporting guidance, a 27-item checklist, an abstract checklist, and revised flow diagrams for reviews.

BMJ-BRITISH MEDICAL JOURNAL (2021)

Add to Collection

Article Clinical Neurology

An Analysis of the Potential Relationship of Triglyceride Glucose and Body Mass Index With Stroke Prognosis

Zongyi Hou et al.

Summary: The study found that overweight/obese patients with ischemic stroke have significantly lower all-cause mortality than low/normal weight patients, and this difference is not associated with the TYG index. Additionally, no association between BMI and TYG index was found.

FRONTIERS IN NEUROLOGY (2021)

Add to Collection

Article Cardiac & Cardiovascular Systems

Association between triglyceride-glucose index and risk of arterial stiffness: a cohort study

Shouling Wu et al.

Summary: The study found that higher TyG index was significantly associated with increased baseline baPWV and annual growth rate of baPWV. Participants with higher TyG index had a higher risk of arterial stiffness progression.

CARDIOVASCULAR DIABETOLOGY (2021)

Add to Collection

Article Clinical Neurology

High Triglyceride Glucose Index Is Associated with Poor Outcomes in Ischemic Stroke Patients after Reperfusion Therapy

Minwoo Lee et al.

Summary: The triglyceride glucose index (TyG index) is a reliable marker of insulin resistance that can predict poor functional outcomes after acute ischemic stroke (AIS) in patients who undergo reperfusion therapy. High TyG index levels may indicate a higher risk of poor functional outcomes for AIS patients receiving reperfusion therapy.

CEREBROVASCULAR DISEASES (2021)

Add to Collection

Article Multidisciplinary Sciences

High triglyceride-glucose index is associated with early recurrent ischemic lesion in acute ischemic stroke

Ki-Woong Nam et al.

Summary: The study found a significant association between the TyG index and early recurrent ischemic lesions in patients with acute ischemic stroke, particularly in the ERIL-same group. Patients with ERIL in the intracranial and extracranial large artery atherosclerosis groups had significantly higher TyG index values compared to those without ERIL.

SCIENTIFIC REPORTS (2021)

Add to Collection

Review Clinical Neurology

Effects of vitamin E on stroke: a systematic review with meta-analysis and trial sequential analysis

Hong Chuan Loh et al.

Summary: The study found that there was no significant difference in the risk reduction of stroke between vitamin E supplementation and placebo/no vitamin E, but there may be some benefits in preventing ischemic stroke. However, more studies are needed to ensure the accuracy of the results, as demonstrated by trial sequential analysis.

STROKE AND VASCULAR NEUROLOGY (2021)

Add to Collection

Article Cardiac & Cardiovascular Systems

Value of triglyceride-glucose index for the estimation of ischemic stroke risk: Insights from a general population

Wenrui Shi et al.

NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES (2020)

Add to Collection

Review Endocrinology & Metabolism

Diagnostic Accuracy of the Triglyceride and Glucose Index for Insulin Resistance: A Systematic Review

Adriana Sanchez-Garcia et al.

INTERNATIONAL JOURNAL OF ENDOCRINOLOGY (2020)

Add to Collection

Article Endocrinology & Metabolism

Causal associations of insulin resistance with coronary artery disease and ischemic stroke: a Mendelian randomization analysis

Weiqi Chen et al.

BMJ OPEN DIABETES RESEARCH & CARE (2020)

Add to Collection

Article Clinical Neurology

Triglyceride Glucose Index and Prognosis of Patients With Ischemic Stroke

Yimo Zhou et al.

FRONTIERS IN NEUROLOGY (2020)

Add to Collection

Review Nutrition & Dietetics

Biomarker of dietary linoleic acid and risk for stroke: A systematic review and meta-analysis

Wanting Zhang et al.

NUTRITION (2020)

Add to Collection

Article Medicine, General & Internal

The triglyceride glucose index is a simple and low-cost marker associated with atherosclerotic cardiovascular disease: a population-based study

Sangmo Hong et al.

BMC MEDICINE (2020)

Add to Collection

Article Cardiac & Cardiovascular Systems

Estimate of prevalent ischemic stroke from triglyceride glucose-body mass index in the general population

Zhi Du et al.

BMC CARDIOVASCULAR DISORDERS (2020)

Add to Collection

Article Medicine, General & Internal

Triglyceride-Glucose Index Linked to Hospital Mortality in Critically Ill Stroke: An Observational Multicentre Study on eICU Database

Bingjun Zhang et al.

FRONTIERS IN MEDICINE (2020)

Add to Collection

Review Gastroenterology & Hepatology

Unexpected Rapid Increase in the Burden of NAFLD in China From 2008 to 2018: A Systematic Review and Meta-Analysis

Feng Zhou et al.

HEPATOLOGY (2019)

Add to Collection

Article Cardiac & Cardiovascular Systems

Triglyceride-glucose index is associated with symptomatic coronary artery disease in patients in secondary care

Alessandra da Silva et al.

CARDIOVASCULAR DIABETOLOGY (2019)

Add to Collection

Article Medicine, General & Internal

Ischaemic stroke

Bruce C. Campbell et al.

NATURE REVIEWS DISEASE PRIMERS (2019)

Add to Collection

Review Clinical Neurology

Clinical and Imaging Predictors of Recurrent Ischemic Stroke: A Systematic Review and Meta-Analysis

Frans Kauw et al.

CEREBROVASCULAR DISEASES (2018)

Add to Collection

Editorial Material Medicine, General & Internal

Guidelines for Adult Stroke Rehabilitation and Recovery

Michelle Gittler et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2018)

Add to Collection

Article Medicine, General & Internal

Clopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA

S. Claiborne Johnston et al.

NEW ENGLAND JOURNAL OF MEDICINE (2018)

Add to Collection

Article Neurosciences

Association Between Plasminogen Activator Inhibitor-1 Genetic Polymorphisms and Stroke Susceptibility

Xin Hu et al.

MOLECULAR NEUROBIOLOGY (2017)

Add to Collection

Article Physiology

Chronic intermittent hypoxia accelerates coronary microcirculatory dysfunction in insulin-resistant Goto-Kakizaki rats

Yi Ching Chen et al.

AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2016)

Add to Collection

Article Surgery

Effect of CYP2C19 Polymorphisms on the Platelet Response to Clopidogrel and Influence on the Effect of High Versus Standard Dose Clopidogrel in Carotid Artery Stenting

A. Gonzalez et al.

EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY (2016)

Add to Collection

Article Physiology

Insulin resistance is associated with tissue-specific regulation of HIF-1α and HIF-2α during mild chronic intermittent hypoxia

J. F. Sacramento et al.

RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY (2016)

Add to Collection

Review Clinical Neurology

Guidelines for Adult Stroke Rehabilitation and Recovery A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association

Carolee J. Winstein et al.

STROKE (2016)

Add to Collection

Article Clinical Neurology

Higher Insulin Resistance Level is Associated with Worse Clinical Response in Acute Ischemic Stroke Patients Treated with Intravenous Thrombolysis

Demet Funda Bas et al.

TRANSLATIONAL STROKE RESEARCH (2016)

Add to Collection

Article Cardiac & Cardiovascular Systems

Loss of the insulin receptor in murine megakaryocytes/platelets causes thrombocytosis and alterations in IGF signalling

Samantha F. Moore et al.

CARDIOVASCULAR RESEARCH (2015)

Add to Collection

Article Cell Biology

Deletion of Macrophage Vitamin D Receptor Promotes Insulin Resistance and Monocyte Cholesterol Transport to Accelerate Atherosclerosis in Mice

Jisu Oh et al.

CELL REPORTS (2015)

Add to Collection

Article Physiology

Platelet hemostasis in patients with metabolic syndrome and type 2 diabetes mellitus: cGMP- and NO-dependent mechanisms in the insulin-mediated platelet aggregation

Tatiana E. Suslova et al.

FRONTIERS IN PHYSIOLOGY (2015)

Add to Collection

Article Cardiac & Cardiovascular Systems

Insulin resistance negatively affects long-term outcome in non-diabetic patients with coronary artery disease after therapies to reduce atherosclerotic risk factors

Yoshinobu Kitta et al.

JOURNAL OF CARDIOLOGY (2013)

Add to Collection

Article Medicine, General & Internal

Clopidogrel with Aspirin in Acute Minor Stroke or Transient Ischemic Attack

Yongjun Wang et al.

NEW ENGLAND JOURNAL OF MEDICINE (2013)

Add to Collection

Review Cell Biology

Insulin Resistance, Hyperglycemia, and Atherosclerosis

Karin E. Bornfeldt et al.

CELL METABOLISM (2011)

Add to Collection

Article Clinical Neurology

Insulin Resistance and Risk of Ischemic Stroke Among Nondiabetic Individuals From the Northern Manhattan Study

Tatjana Rundek et al.

ARCHIVES OF NEUROLOGY (2010)

Add to Collection

Review Endocrinology & Metabolism

Insulin, Insulin Resistance, and Platelet Signaling in Diabetes

Voahanginirina Randriamboavonjy et al.

DIABETES CARE (2009)

Add to Collection

Article Medicine, Research & Experimental

The Product of Fasting Glucose and Triglycerides As Surrogate for Identifying Insulin Resistance in Apparently Healthy Subjects

Luis E. Simental-Mendía et al.

Metabolic Syndrome and Related Disorders (2008)

Add to Collection

Article Biology

Trim and fill: A simple funnel-plot-based method of testing and adjusting for publication bias in meta-analysis

S Duval et al.

BIOMETRICS (2000)

Add to Collection

© Peeref 2019-2024. All rights reserved.