Related references
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Review
Clinical Neurology
The oncogenic fusion landscape in pediatric CNS neoplasms
Mieke Roosen et al.
Summary: Pediatric neoplasms in the central nervous system (CNS) are a leading cause of cancer-related deaths in children. Recent molecular analyses have improved diagnosis and risk stratification of CNS tumors. Fusion proteins and oncogenic drivers are important in pediatric tumorigenesis.
ACTA NEUROPATHOLOGICA (2022)
Article
Clinical Neurology
PATZ1 fusions define a novel molecularly distinct neuroepithelial tumor entity with a broad histological spectrum
Karam T. Alhalabi et al.
Summary: Large-scale molecular profiling studies have revealed greater heterogeneity in CNS tumors than expected, with DNA methylation profiling being a useful tool for robust tumor classification. A subset of CNS tumors carrying PATZ1 fusions have been identified, showing a distinct molecular class with intermediate prognosis.
ACTA NEUROPATHOLOGICA (2021)