Autologous hematopoietic cell transplantation as a part of a sequential multi-phase therapeutic approach (R-COPADM/CYVE/ASCT) as first-line treatment of high-grade B-cell lymphoma: results of a retrospective study with long-term follow-up

Article Oncology

Targeting of inflammatory pathways with R2CHOP in high-risk DLBCL

Keenan T. Hartert et al.

Summary: A study identified a high-risk subset of non-GCB DLBCL patients with genomic alterations and expression signatures affecting treatment outcomes, showing unfavorable prognoses with RCHOP therapy. However, these high-risk patients had better outcomes when lenalidomide was added to RCHOP treatment.

LEUKEMIA (2021)

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Article Oncology

Risk Stratification for Diffuse Large B-Cell Lymphoma by Integrating Interim Evaluation and International Prognostic Index: A Multicenter Retrospective Study

Xue Shi et al.

Summary: The study evaluated the prognostic relevance of early risk stratification in DLBCL patients and developed a new stratification system combining an interim evaluation and IPI. The combined risk stratification system separated patients into different risk groups with significant differences in overall survival and progression-free survival rates.

FRONTIERS IN ONCOLOGY (2021)

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Article Oncology