Journal
CATALYSIS COMMUNICATIONS
Volume 61, Issue -, Pages 26-30Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.catcom.2014.12.005
Keywords
Heterogeneous catalysis; Multicomponent reaction; One-pot synthesis; Green chemistry; CuO/ZrO2; Reusable catalyst
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Funding
- National Research Foundation of South Africa
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A CuO/ZrO2 catalyzed eco-friendly strategy for the synthesis of pyrazole-4-carbonitrile derivatives in aqueous media in excellent yields (88-92%) is described. The catalyst was characterized by X-ray diffraction (XRD) patterns, Scanning electron microscopy (SEM), Transmission electron microscopy (TEM) and BET surface area analysis. The main benefits of one-pot three component protocol are short reaction times (<2 h), simple workup procedure, safety and recyclable catalyst. The catalyst is inexpensive, fully recyclable and reusable for over 5 runs, preserving its high activity. (C) 2014 Elsevier B.V. All rights reserved.
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