4.7 Review

Plants-based medicine implication in the evolution of chronic liver diseases

Journal

BIOMEDICINE & PHARMACOTHERAPY
Volume 158, Issue -, Pages -

Publisher

ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
DOI: 10.1016/j.biopha.2022.114207

Keywords

Herbal medicine; Plants-based active compounds; Dietary supplements; Non-alcoholic fatty liver disease; Chronic liver diseases; Hepatitis; Liver fibrosis; Liver cirrhosis

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Hepatic disorders are significant health problems with high incidence and increased risk of chronicling or death. Many patients with chronic liver diseases use herbal medicines in parallel with allopathic treatment. This paper provides a thorough analysis of studies on medicinal plants, bioactive compounds, and the activity of herbal medicines in the evolution of chronic liver diseases. However, there is often a lack of comprehensive data on illness progression and patient living standards, which should be considered when evaluating the long-term effects of herbal treatments on the health and quality of life of individuals with liver disease. Bioactive phytocomponents may be a valuable source for developing novel medications, but further research is needed to assess safety, effectiveness, and standardization for therapeutic management of liver illnesses.
Hepatic disorders are considered major health problems, due to their high incidence, increased risk of chroni-cling or death and the costs involved in therapies. A large number of patients with chronic liver diseases use herbal medicines and dietary supplements in parallel with allopathic treatment. The current review provides a thorough analysis of the studies conducted on the most important species of medicinal plants used in this disease, bioactive compounds and on the activity of herbal medicines in the evolution of chronic liver diseases. However, a negative aspect is that there is frequently a lack of comprehensive data on the progression of the illness and the living standards of patients who are affected when evaluating the effects of these phytocomponents on the evolution of chronic liver disease, the patients' health, and their quality of life. It is essential to take this impairment into account when evaluating the long-term effects of herbal treatments on the health of individuals who suffer from liver illness. Bioactive phytocomponents may be a suitable source for the development of novel medications due to the correlation between traditional uses and medical advances. Additional high-quality preclinical examinations utilizing cutting-edge approaches are needed to assess safety and effectiveness and to detect, categorize, and standardize the active substances and their formulations for the most suitable therapeutic management of liver illnesses.

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