Related references
Note: Only part of the references are listed.The Death Receptor Pathway of Apoptosis
Douglas R. Green
Cold Spring Harbor Perspectives in Biology (2022)
Antidepressants Fluoxetine Mediates Endoplasmic Reticulum Stress and Autophagy of Non-Small Cell Lung Cancer Cells Through the ATF4-AKT-mTOR Signaling Pathway
Shali Shao et al.
FRONTIERS IN PHARMACOLOGY (2022)
The antidepressant imipramine inhibits breast cancer growth by targeting estrogen receptor signaling and DNA repair events
Santosh Timilsina et al.
CANCER LETTERS (2022)
Antiproliferative Effects of St. John's Wort, Its Derivatives, and Other Hypericum Species in Hematologic Malignancies
Alessandro Allegra et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)
Anti-Tumor Activity of Hypericum perforatum L. and Hyperforin through Modulation of Inflammatory Signaling, ROS Generation and Proton Dynamics
Marta Menegazzi et al.
ANTIOXIDANTS (2021)
The selective serotonin reuptake inhibitors enhance the cytotoxicity of sorafenib in hepatocellular carcinoma cells
Huan Zhang et al.
ANTI-CANCER DRUGS (2021)
The proliferation effects of fluoxetine and amitriptyline on human breast cancer cells and the underlying molecular mechanisms
Bingli Lei et al.
ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY (2021)
Suppression of EGFR/PKC-δ/NF-κB Signaling Associated With Imipramine-Inhibited Progression of Non-Small Cell Lung Cancer
Po-Fu Yueh et al.
FRONTIERS IN ONCOLOGY (2021)
Discovery of sertraline and its derivatives able to combat drug-resistant gastric cancer cell via inducing apoptosis
Chao Mu et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2021)
Synergistic Growth Inhibition of HT-29 Colon and MCF-7 Breast Cancer Cells with Simultaneous and Sequential Combinations of Antineoplastics and CNS Drugs
Diana Duarte et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)
Imipramine impedes glioma progression by inhibiting YAP as a Hippo pathway independent manner and synergizes with temozolomide
Yan Wang et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2021)
Sensitizing TRAIL-resistant A549 lung cancer cells and enhancing TRAIL-induced apoptosis with the antidepressant amitriptyline
K. M. A. Zinnah et al.
ONCOLOGY REPORTS (2021)
Repositioning of duloxetine to target pancreatic stellate cells
Akiko Sagara et al.
ONCOLOGY LETTERS (2021)
Pimozide and Imipramine Blue Exploit Mitochondrial Vulnerabilities and Reactive Oxygen Species to Cooperatively Target High Risk Acute Myeloid Leukemia
Zhengqi Wang et al.
ANTIOXIDANTS (2021)
Fluoxetine Simultaneously Induces Both Apoptosis and Autophagy in Human Gastric Adenocarcinoma Cells
Wah Wah Po et al.
BIOMOLECULES & THERAPEUTICS (2020)
Apoptotic effect of fluoxetine through the endoplasmic reticulum stress pathway in the human gastric cancer cell line AGS
Phyu Phyu Khin et al.
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2020)
New role of the antidepressant imipramine as a Fascin1 inhibitor in colorectal cancer cells
Begona Alburquerque-Gonzalez et al.
EXPERIMENTAL AND MOLECULAR MEDICINE (2020)
Blockage of Autophagic Flux and Induction of Mitochondria Fragmentation by Paroxetine Hydrochloride in Lung Cancer Cells Promotes Apoptosis via the ROS-MAPK Pathway
Kun Wang et al.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2020)
Induction of apoptosis through extrinsic/intrinsic pathways and suppression of ERK/NF-κB signalling participate in anti-glioblastoma of imipramine
Fei-Ting Hsu et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2020)
The MAO inhibitors phenelzine and clorgyline revert enzalutamide resistance in castration resistant prostate cancer
Keliang Wang et al.
NATURE COMMUNICATIONS (2020)
Beneficial effect of fluoxetine on anti-tumor progression on hepatocellular carcinoma and non-small cell lung cancer bearing animal model
Li-Cho Hsu et al.
BIOMEDICINE & PHARMACOTHERAPY (2020)
Inhibition of autophagy flux by sertraline attenuates TRAIL resistance in lung cancer via death receptor 5 upregulation
Kazi Mohammad Ali Zinnah et al.
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2020)
Duloxetine improves cancer-associated pain in a mouse model of pancreatic cancer through stimulation of noradrenaline pathway and its antitumor effects
Ichie Kajiwara et al.
PAIN (2020)
Imipramine Inhibits Migration and Invasion in Metastatic Castration-Resistant Prostate Cancer PC-3 Cells via AKT-Mediated NF-κB Signaling Pathway
Eun Yeong Lim et al.
MOLECULES (2020)
St. John's Wort Suppresses Growth in Triple-Negative Breast Cancer Cell Line MDA-MB-231 by Inducing Prodeath Autophagy and Apoptosis
Mikyoung You et al.
NUTRIENTS (2020)
Lactic Acid and an Acidic Tumor Microenvironment suppress Anticancer Immunity
Joy X. Wang et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
The PI3K-AKT network at the interface of oncogenic signalling and cancer metabolism
Gerta Hoxhaj et al.
NATURE REVIEWS CANCER (2020)
IDO1 and Kynurenine Pathway Metabolites Activate PI3K-Akt Signaling in the Neoplastic Colon Epithelium to Promote Cancer Cell Proliferation and Inhibit Apoptosis
Kumar S. Bishnupuri et al.
CANCER RESEARCH (2019)
Is there any potential anticancer effect of raloxifene and fluoxetine on DMBA-induced rat breast cancer?
Oguzhan Tatar et al.
JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY (2019)
Salvianolic acid A attenuates CCl4-induced liver fibrosis by regulating the PI3K/AKT/mTOR, Bcl-2/Bax and caspase-3/cleaved caspase-3 signaling pathways
Rong Wang et al.
DRUG DESIGN DEVELOPMENT AND THERAPY (2019)
Fluoxetine Enhances Anti-tumor Activity of Paclitaxel in Gastric Adenocarcinoma Cells by Triggering Apoptosis and Necroptosis
Tin Myo Khing et al.
ANTICANCER RESEARCH (2019)
Duloxetine Enhances TRAIL-mediated Apoptosis via AMPK-mediated Inhibition of Autophagy Flux in Lung Cancer Cells
K. M. A. Zinnah et al.
ANTICANCER RESEARCH (2019)
Anticancer activity of paroxetine in human colon cancer cells: Involvement of MET and ERBB3
Won-Jun Jang et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2019)
Paroxetine Induces Apoptosis of Human Breast Cancer MCF-7 Cells through Ca2+-and p38 MAP Kinase-Dependent ROS Generation
Young-Woo Cho et al.
CANCERS (2019)
Inflammation and Cancer
Nitin Singh et al.
ANNALS OF AFRICAN MEDICINE (2019)
The broken cycle: E2F dysfunction in cancer
Lindsey N. Kent et al.
NATURE REVIEWS CANCER (2019)
Amitriptyline modulated Ca2+ signaling and induced Ca2+-independent cell viability in human osteosarcoma cells
T. Lu et al.
HUMAN & EXPERIMENTAL TOXICOLOGY (2018)
The Use of Antidepressants for Physical and Psychological Symptoms in Cancer
Syahrir Zaini et al.
CURRENT DRUG TARGETS (2018)
St. John's Wort Regulates Proliferation and Apoptosis in MCF-7 Human Breast Cancer Cells by Inhibiting AMPK/mTOR and Activating the Mitochondrial Pathway
Mi-Kyoung You et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)
Repurposing sertraline sensitizes non-small cell lung cancer cells to erlotinib by inducing autophagy
Xingwu Jiang et al.
JCI INSIGHT (2018)
The antidepressant fluoxetine induces necrosis by energy depletion and mitochondrial calcium overload
Emilie Charles et al.
ONCOTARGET (2017)
Amitriptyline down-regulates coenzyme Q10 biosynthesis in lung cancer cells
Tamara Ortiz et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2017)
Assessment of citalopram and escitalopram on neuroblastoma cell lines: Cell toxicity and gene modulation
Laurent Sakka et al.
ONCOTARGET (2017)
Imipramine blue sensitively and selectively targets FLT3-ITD positive acute myeloid leukemia cells
Jonathan Metts et al.
SCIENTIFIC REPORTS (2017)
Anti-Cancer Effects of Citalopram on Hepatocellular Carcinoma Cells Occur via Cytochrome C Release and the Activation of NF-kB
Elham Ahmadian et al.
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY (2017)
Fluoxetine induces apoptosis through endoplasmic reticulum stress via mitogen-activated protein kinase activation and histone hyperacetylation in SK-N-BE(2)-M17 human neuroblastoma cells
Ji Hyun Choi et al.
APOPTOSIS (2017)
Baicalein increases cisplatin sensitivity of A549 lung adenocarcinoma cells via PI3K/Akt/NF-κB pathway
Meiling Yu et al.
BIOMEDICINE & PHARMACOTHERAPY (2017)
A current perspective on the oncopreventive and oncolytic properties of selective serotonin reuptake inhibitors
Daniel P. Radin et al.
BIOMEDICINE & PHARMACOTHERAPY (2017)
Global Cancer Incidence and Mortality Rates and Trends-An Update
Lindsey A. Torre et al.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION (2016)
Imipramine blue halts head and neck cancer invasion through promoting F-box and leucine-rich repeat protein 14-mediated Twist1 degradation
W-H Yang et al.
ONCOGENE (2016)
Inhibition of FoxM1-Mediated DNA Repair by Imipramine Blue Suppresses Breast Cancer Growth and Metastasis
Subapriya Rajamanickam et al.
CLINICAL CANCER RESEARCH (2016)
Fluoxetine regulates cell growth inhibition of interferon-α
Yu-Min Lin et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2016)
Fluoxetine synergizes with temozolomide to induce the CHOP-dependent endoplasmic reticulum stress-related apoptosis pathway in glioma cells
Jian Ma et al.
ONCOLOGY REPORTS (2016)
Ameliorative potential of fluoxetine/raloxifene combination on experimentally induced breast cancer
Ahmed M. Kabel et al.
TISSUE & CELL (2016)
Histone Modifications and Cancer
James E. Audia et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2016)
St. John's Wort Attenuates Colorectal Carcinogenesis in Mice through Suppression of Inflammatory Signaling
Soumen K. Manna et al.
CANCER PREVENTION RESEARCH (2015)
Reactive oxygen species in the tumor niche triggers altered activation of macrophages and immunosuppression: Role of fluoxetine
Sayan Ghosh et al.
CELLULAR SIGNALLING (2015)
Oncostatic effects of fluoxetine in experimental colon cancer models
Vinicius Kannen et al.
CELLULAR SIGNALLING (2015)
Nortriptyline induces mitochondria and death receptor-mediated apoptosis in bladder cancer cells and inhibits bladder tumor growth in vivo
Sheau-Yun Yuan et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2015)
Fluoxetine, an antidepressant, suppresses glioblastoma by evoking AMPAR-mediated calcium-dependent apoptosis
Kao-Hui Liu et al.
ONCOTARGET (2015)
Modulating cancer multidrug resistance by sertraline in combination with a nanomedicine
Velthe Drinberg et al.
CANCER LETTERS (2014)
Suppression of metastasis by mirtazapine via restoration of the Lin-7C/β-catenin pathway in human cancer cells
Katsuhiro Uzawa et al.
SCIENTIFIC REPORTS (2014)
Antidepressant fluoxetine and its potential against colon tumors
Helga Stopper et al.
WORLD JOURNAL OF GASTROINTESTINAL ONCOLOGY (2014)
The Role of Paroxetine in Fatigue and Depression of Patients Under Chemotherapeutic Treatment
Panagiotis Heras et al.
AMERICAN JOURNAL OF THERAPEUTICS (2013)
The tricyclic antidepressant amitriptyline is cytotoxic to HTB114 human leiomyosarcoma and induces p75NTR-dependent apoptosis
Grazia Pula et al.
ANTI-CANCER DRUGS (2013)
The antidepressant amitriptyline shows potent therapeutic activity against multiple myeloma
Zubin Zhang et al.
ANTI-CANCER DRUGS (2013)
Amitriptyline may have a supportive role in cancer treatment by inhibiting glutathione S-transferase pi (GST-π) and alpha (GST-α)
Gulnihal Kulaksiz-Erkmen et al.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (2013)
A Drug Repositioning Approach Identifies Tricyclic Antidepressants as Inhibitors of Small Cell Lung Cancer and Other Neuroendocrine Tumors
Nadine S. Jahchan et al.
CANCER DISCOVERY (2013)
DNA-Binding Studies of Fluoxetine Antidepressant
Soheila Kashanian et al.
DNA AND CELL BIOLOGY (2012)
Systematic Analysis of Cell Cycle Effects of Common Drugs Leads to the Discovery of a Suppressive Interaction between Gemfibrozil and Fluoxetine
Scott A. Hoose et al.
PLOS ONE (2012)
Mirtazapine Inhibits Tumor Growth via Immune Response and Serotonergic System
Chun-Kai Fang et al.
PLOS ONE (2012)
The tricyclic antidepressant imipramine induces autophagic cell death in U-87MG glioma cells
Seung-Hyun Jeon et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2011)
Oral administration of fluoxetine alters the proliferation/apoptosis balance of lymphoma cells and up-regulates T cell immunity in tumor-bearing mice
Luciana Romina Frick et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2011)
The Tricyclic Antidepressant Amitriptyline Inhibits D-Cyclin Transactivation and Induces Myeloma Cell Apoptosis by Inhibiting Histone Deacetylases: In Vitro and In Silico Evidence
Xinliang Mao et al.
MOLECULAR PHARMACOLOGY (2011)
Drug Interaction in Psycho-Oncology: Antidepressants and Antineoplastics
C. Miguel et al.
PHARMACOLOGY (2011)
Fluoxetine induces preventive and complex effects against colon cancer development in epithelial and stromal areas in rats
Vinicius Kannen et al.
TOXICOLOGY LETTERS (2011)
Acute oxidant damage promoted on cancer cells by amitriptyline in comparison with some common chemotherapeutic drugs
Mario David Cordero et al.
ANTI-CANCER DRUGS (2010)
Fluoxetine Induces Apoptosis in Ovarian Carcinoma Cell Line OVCAR-3 Through Reactive Oxygen Species-Dependent Activation of Nuclear Factor-κB
Chung Soo Lee et al.
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY (2010)
SLC6A4 expression and anti-proliferative responses to serotonin transporter ligands chlomipramine and fluoxetine in primary B-cell malignancies
Anita Chamba et al.
LEUKEMIA RESEARCH (2010)
Fluoxetine mediates G0/G1 arrest by inducing functional inhibition of cyclin dependent kinase subunit (CKS)1
Anand Krishnan et al.
BIOCHEMICAL PHARMACOLOGY (2008)
Inhibitory effect of fluoxetine on lymphoma growth through the modulation of antitumor T-cell response by serotonin-dependent and independent mechanisms
Luciana Romina Frick et al.
BIOCHEMICAL PHARMACOLOGY (2008)
The role of mitochondria in apoptosis
Seon-Yong Jeong et al.
BMB REPORTS (2008)
Fluoxetine inhibits the extracellular signal regulated kinase pathway and suppresses growth of cancer cells
Andrzej Stepulak et al.
CANCER BIOLOGY & THERAPY (2008)
Tricyclic antidepressant pharmacology and therapeutic drug interactions updated
P. K. Gillman
BRITISH JOURNAL OF PHARMACOLOGY (2007)
Paroxetine-induced apoptosis in human osteosarcoma cells:: Activation of p38 MAP kinase and caspase-3 pathways without involvement of [Ca2+]i elevation
Chiang-Ting Chou et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2007)
Review of the epidemiological literature on antidepressant use and breast cancer risk
Patricia F. Coogan
EXPERT REVIEW OF NEUROTHERAPEUTICS (2006)
Differential induction of apoptosis by antidepressants in glioma and neuroblastoma cell lines - Evidence for p-c-Jun, cytochrome c, and caspase-3 involvement
Y Levkovitz et al.
JOURNAL OF MOLECULAR NEUROSCIENCE (2005)
Mechanism of block of hEag1 K+ channels by imipramine and astemizole
RE García-Ferreiro et al.
JOURNAL OF GENERAL PHYSIOLOGY (2004)
Fluoxetine inhibits multidrug resistance extrusion pumps and enhances responses to chemotherapy in syngeneic and in human xenograft mouse tumor models
D Peer et al.
CANCER RESEARCH (2004)
Selective serotonin reuptake inhibitors directly signal for apoptosis in biopsy-like Burkitt lymphoma cells
A Serafeim et al.
BLOOD (2003)
Anti- and pro-inflammatory considerations in antidepressant use during medical illness: bupropion lowers and mirtazapine increases circulating tumor necrosis factor-alpha levels
RE Kast
GENERAL HOSPITAL PSYCHIATRY (2003)
5-hydroxytryptamine drives apoptosis in biopsylike Burkitt lymphoma cells: reversal by selective serotonin reuptake inhibitors
A Serafeim et al.
BLOOD (2002)
Inhibition of tumour cell growth by hyperforin, a novel anticancer drug from St. John's wort that acts by induction of apoptosis
CM Schempp et al.
ONCOGENE (2002)
Mechanisms of caspase activation and inhibition during apoptosis
YG Shi
MOLECULAR CELL (2002)
Akt protects mouse hepatocytes from TNF-α- and Fas-mediated apoptosis through NK-κB activation
E Hatano et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2001)
Catalytic inhibition of human DNA topoisomerase IIα by hypericin, a naphthodianthrone from St. John's wort (Hypericum perforatum)
KA Peebles et al.
BIOCHEMICAL PHARMACOLOGY (2001)
Share Paper
