4.7 Review

Nanoparticle-mediated therapeutic management in cholangiocarcinoma drug targeting: Current progress and future prospects

Related references

Note: Only part of the references are listed.
Article Pharmacology & Pharmacy

Effect and Mechanism of the Lenvatinib@H-MnO2-FA Drug Delivery System in Targeting Intrahepatic Cholangiocarcinoma

Zhouyu Ning et al.

Summary: In this study, a Lenvatinib@H-MnO2-FA drug delivery system was successfully synthesized, which effectively inhibited ICC cell proliferation and promoted apoptosis. This system shows promise as a drug delivery nano-vehicle.

CURRENT PHARMACEUTICAL DESIGN (2022)

Article Oncology

Macrophages-aPKCι-CCL5 Feedback Loop Modulates the Progression and Chemoresistance in Cholangiocarcinoma

Tao Yang et al.

Summary: This study reveals the role of Macrophages-aPKC (iota)-CCL5 Feedback Loop in cholangiocarcinoma (CCA) and suggests a novel therapeutic strategy of aPKC (iota)-siRNA and gemcitabine co-delivered by liposomes for CCA.

JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2022)

Article Oncology

Paclitaxel Restores Sensitivity to Chemotherapy in Preclinical Models of Multidrug-Resistant Intrahepatic Cholangiocarcinoma

Annamaria Massa et al.

Summary: The study demonstrates that paclitaxel has anti-tumor activity in multidrug-resistant intrahepatic cholangiocarcinoma by affecting the cell cycle and inducing apoptosis, impairing the stem cell compartment. A therapeutic regimen containing albumin-bound nanoparticle paclitaxel overcomes drug resistance and delays tumor growth, reducing glucose uptake.

FRONTIERS IN ONCOLOGY (2022)

Article Engineering, Biomedical

Peptide ligand-SiO2 microspheres with specific affinity for phosphatidylserine as a new strategy to isolate exosomes and application in proteomics to differentiate hepatic cancer

Kaige Yang et al.

Summary: A novel separation strategy for exosomes is proposed based on the specific interaction between immobilized peptide ligands and phosphatidylserine moieties on the exosome surface. The method allows for high yield recovery of intact exosome samples in a short processing time, with higher purity compared to other isolation methods. The method also reduces the co-isolation of contaminants.

BIOACTIVE MATERIALS (2022)

Article Oncology

Nanoliposomal irinotecan in combination with leucovorin and 5-fluorouracil in advanced biliary tract cancers

Gabriel Allo et al.

Summary: Biliary tract cancers are rare but aggressive, and current treatment options have limited effectiveness. This study retrospectively analyzed the use of FOLFnal-IRI as a subsequent therapy in patients with advanced biliary tract malignancies, showing promising antitumor potential and an acceptable safety profile.

MOLECULAR AND CLINICAL ONCOLOGY (2022)

Article Surgery

Synchronous double primary malignancies of the pancreatic body and extrahepatic bile duct treated with pancreatoduodenectomy and splenic artery resection following neoadjuvant chemotherapy with gemcitabine plus nab-paclitaxel: a case report

Takahiro Murokawa et al.

Summary: This case report describes a rare case of double primary malignancies involving borderline resectable pancreatic cancer and extrahepatic bile duct cancer. The patient underwent neoadjuvant chemotherapy and function-preserving surgery, achieving favorable outcomes.

SURGICAL CASE REPORTS (2022)

Review Medicine, Research & Experimental

Exosomes in the tumor microenvironment of cholangiocarcinoma: current status and future perspectives

Kai Zhao et al.

Summary: Cholangiocarcinoma is an aggressive malignancy with a high fatality rate. Exosomes, as communication messengers, play important roles in tumor microenvironment and have potential value in the diagnosis and treatment of cholangiocarcinoma.

JOURNAL OF TRANSLATIONAL MEDICINE (2022)

Article Radiology, Nuclear Medicine & Medical Imaging

A Pilot First-in-Human Study of Embrace, a Polyethylene Glycol-Based Liquid Embolic Agent, in the Embolization of Malignant and Benign Hypervascular Tumors

Gerard S. Goh et al.

Summary: The study investigated the safety and efficacy of Embrace Hydrogel Embolic System (HES) in the treatment of benign and malignant hypervascular tumors. The results showed a 100% technical success rate with HES, indicating its effectiveness in embolization. The product was found to be easy to use, and there were no cases of target vessel recanalization on follow-up imaging at 30 days.

JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY (2022)

Article Oncology

Mesenchymal stem cell-derived exosomes loaded with 5-Fu against cholangiocarcinoma in vitro

Mingzheng Chen et al.

Summary: The study demonstrated the successful loading of 5-Fu drug into exosomes derived from human bone marrow mesenchymal stem cells, which significantly inhibited the growth of CCA cells, indicating the potential therapeutic value of exosomes in chemotherapy.

MOLECULAR MEDICINE REPORTS (2022)

Review Biochemistry & Molecular Biology

Lipid-Based Drug Delivery Systems for Diseases Managements

Douweh Leyla Gbian et al.

Summary: This article extensively discusses the physicochemical properties, formulation methods, characteristics, mechanisms of action, and large-scale manufacturing of liposomes as delivery systems, as well as the benefits, toxicity, and limitations of their use in pharmacotherapeutics. It also describes experimental approaches to reduce or bypass the drawbacks of liposomal drugs and discusses their application in the treatment of various diseases.

BIOMEDICINES (2022)

Article Oncology

Nanomaterials multifunctional behavior for enlightened cancer therapeutics

Ganji Seeta Rama Raju et al.

Summary: Cancer is a deadly disease with limitations in traditional therapies. Nanotechnology, as an emerging science, provides more effective cancer treatments by overcoming biomedical and biophysical barriers.

SEMINARS IN CANCER BIOLOGY (2021)

Article Pharmacology & Pharmacy

Enhanced oral bioavailability and biodistribution of atractylodin encapsulated in PLGA nanoparticle in cholangiocarcinoma

Abdifetah Ibrahim Omar et al.

Summary: The study demonstrated the promising anticancer activity of ATD-loaded PLGA nanoparticles against cholangiocarcinoma cells and the superior pharmacokinetic profile of radiolabelled Tc-99m-ATD-PLGA in mice, suggesting PLGA NPs as a suitable drug delivery carrier for CCA treatment.

CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY (2021)

Article Biochemistry & Molecular Biology

In Vitro Photodynamic Effects of the Inclusion Nanocomplexes of Glucan and Chlorin e6 on Atherogenic Foam Cells

Jae Won Ahn et al.

Summary: The study prepared Glu/Ce6 nanocomplexes capable of inducing apoptosis of foam cells, which release singlet oxygen under laser irradiation, leading to significant membrane damage and apoptosis of foam cells.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

Article Biochemistry & Molecular Biology

Cytocompatibility of Modified Silk Fibroin with Glycidyl Methacrylate for Tissue Engineering and Biomedical Applications

Heesun Hong et al.

Summary: Chemically modified hydrogels are crucial for cell and tissue regeneration, but must be carefully evaluated for biocompatibility. The dialysis periods during chemical modification of natural polymers are essential for removing unreacted chemical residues.

BIOMOLECULES (2021)

Article Spectroscopy

A fluorescence AuNPs-LISA: A new approach for Opisthorchis viverrini (Ov) antigen detection with a simple fluorescent enhancement strategy by surfactant micelle in urine samples

Wichit Taron et al.

Summary: The development of a new fluorescence AuNPs-LISA technique utilizing OPD as a chromogenic substrate and incorporating the non-ionic surfactant Triton X-100 has significantly enhanced the detection sensitivity for OvAg concentration, leading to a 1200-fold improvement compared to the colorimetric AuNPs-LISA. The proposed assay demonstrates high diagnosis sensitivity, specificity, and accuracy, providing a promising tool for the detection, control, and elimination of human opisthorchiasis in endemic areas.

SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY (2021)

Article Multidisciplinary Sciences

PGMD/curcumin nanoparticles for the treatment of breast cancer

Mankamna Kumari et al.

Summary: The study developed PGMD/curcumin nanoparticles for anticancer activity against breast cancer cells, showing effective induction of apoptosis in the cells.

SCIENTIFIC REPORTS (2021)

Review Biochemistry & Molecular Biology

Nucleic Acid Delivery with Red-Blood-Cell-Based Carriers

Giulia Della Pelle et al.

Summary: Gene therapy has the potential to be a significant advancement in 21st-century medicine. Using the body's cells as drug delivery systems offers a unique approach, with red blood cells as a potential candidate due to their abundance and potential cost-effectiveness.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

Article Nanoscience & Nanotechnology

A Highly Efficient One-for-All Nanodroplet for Ultrasound Imaging-Guided and Cavitation-Enhanced Photothermal Therapy

Dui Qin et al.

Summary: A highly efficient nanodroplet with multiple capabilities was developed for cancer therapy, showing advantages in high photothermal conversion efficiency, enhanced US imaging, and acoustic cavitation.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2021)

Article Pharmacology & Pharmacy

Atractylodin inhibited the migration and induced autophagy in cholangiocarcinoma cells via PI3K/AKT/mTOR and p38MAPK signalling pathways

Bishwanath Acharya et al.

Summary: Atractylodin inhibits proliferation and induces autophagy in cholangiocarcinoma cells by regulating the PI3K/AKT/mTOR and p38MAPK signaling pathways.

JOURNAL OF PHARMACY AND PHARMACOLOGY (2021)

Article Multidisciplinary Sciences

Curcumin activates Nrf2 through PKCδ-mediated p62 phosphorylation at Ser351

Jee-Yun Park et al.

Summary: Curcumin activates Nrf2 through phosphorylation of p62 at S351, with PKC delta playing a crucial role in this process.

SCIENTIFIC REPORTS (2021)

Review Pharmacology & Pharmacy

Toxic Mechanisms of Five Heavy Metals: Mercury, Lead, Chromium, Cadmium, and Arsenic

Mahdi Balali-Mood et al.

Summary: Industrial activities of the last century have led to increased human exposure to heavy metals such as mercury, lead, chromium, cadmium, and arsenic, resulting in acute or chronic poisonings through water, air, and food. These heavy metals accumulate in the body, causing toxic effects on various tissues and organs by disrupting cellular events and inducing oxidative stress. Common mechanisms of action of these metals include ROS generation, inhibition of antioxidant defense, enzyme inactivation, and selective binding to specific macromolecules, some leading to genomic instability and carcinogenicity through DNA damage and oxidative stress. Despite current knowledge, heavy metal poisoning incidents remain prevalent, necessitating preventive measures and effective treatment, possibly including chelation therapy.

FRONTIERS IN PHARMACOLOGY (2021)

Review Oncology

Triggered Drug Release From Liposomes: Exploiting the Outer and Inner Tumor Environment

Marina Santiago Franco et al.

Summary: Research has shown that liposomes can serve as potential carriers of anticancer drugs, accumulating passively in the tumor tissue by taking advantage of its characteristics. Different strategies, such as PEGylation and attaching ligands to the liposomal surface, have been employed to improve efficacy.

FRONTIERS IN ONCOLOGY (2021)

Article Biochemistry & Molecular Biology

Synthesis and Evaluation of AlgNa-g-Poly(QCL-co-HEMA) Hydrogels as Platform for Chondrocyte Proliferation and Controlled Release of Betamethasone

Jomarien Garcia-Couce et al.

Summary: Hydrogels obtained from combining different polymers are evaluated for their applicability in controlled release system platforms and tissue engineering scaffolds in this study. Characterization of the hydrogels was done through Fourier transform-infrared spectroscopy, scanning electron microscopy, and analysis of swelling degree. The results show that these hydrogels are promising materials for pharmaceutical and biomedical applications due to their biocompatibility and controlled release behavior.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

Article Biochemistry & Molecular Biology

Kidney-Protector Lipidic Cilastatin Derivatives as Structure-Directing Agents for the Synthesis of Mesoporous Silica Nanoparticles for Drug Delivery

Samuel Martinez-Erro et al.

Summary: Mesoporous silica nanomaterials have promising potential in controlled drug delivery systems due to their ability to selectively transport, protect, and release pharmaceuticals. The concept of drug-structure-directing agent (DSDA) allows for the successful formation of these nanomaterials in a simple, fast, and one-step process, without the need for extra steps. The synthesized mesoporous silica nanoparticles show good sphericity, remarkable textural properties, and slow and sustained drug release, making them a potential drug delivery system for kidney protection during cancer chemotherapy.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

Article Nanoscience & Nanotechnology

Neurite Extension and Orientation of Spiral Ganglion Neurons Can Be Directed by Superparamagnetic Iron Oxide Nanoparticles in a Magnetic Field

Yangnan Hu et al.

Summary: The study focused on physical guidance of neuron orientation and neurite growth using SPIO nanoparticles and magnetic fields. Results indicated the potential of SPIO nanoparticles in promoting neuronal growth and development, offering new possibilities for treating degenerative hearing nerve damage.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2021)

Review Biotechnology & Applied Microbiology

Graphene-based nanomaterials for breast cancer treatment: promising therapeutic strategies

Guangman Cui et al.

Summary: This review highlights the potential applications of graphene-based nanomaterials (GBNs) in the treatment of breast cancer, including drug delivery, gene therapy, and phototherapy, showcasing their advantages in enhancing therapeutic effects, reducing toxicity, overcoming multidrug resistance, and inhibiting tumor metastasis.

JOURNAL OF NANOBIOTECHNOLOGY (2021)

Article Chemistry, Multidisciplinary

Structural and Optical Sensing Properties of Nonthermal Atmospheric Plasma-Synthesized Polyethylene Glycol-Functionalized Gold Nanoparticles

Linh Nhat Nguyen et al.

Summary: Polyethylene glycol-functionalized gold nanoparticles were prepared by a plasma-assisted method without additional reducing chemicals. The gold precursor transformed into Au@PEG NPs colloid that exhibited surface plasma resonance at 530 nm. The rapid, low-cost, and environmentally friendly method will facilitate the application of plasma-synthesized nanomaterials in sensors.

NANOMATERIALS (2021)

Article Chemistry, Multidisciplinary

Chitosan Nanoparticles as a Promising Nanomaterial for Encapsulation of Pomegranate (Punica granatum L.) Peel Extract as a Natural Source of Antioxidants

Maral Soltanzadeh et al.

Summary: Encapsulation of pomegranate peel extract (PPE) in chitosan nanoparticles (CSNPs) provides protection for sensitive constituents, with spherical NPs synthesized successfully exhibiting good physical stability and antioxidant properties. The PPE-loaded CSNPs effectively inhibited the growth of Gram-positive S. aureus, indicating their potential as nanomaterials for controlled delivery of natural antioxidants/antimicrobials in food packaging applications.

NANOMATERIALS (2021)

Review Oncology

Phytochemicals in Chemoprevention: A Cost-Effective Complementary Approach

Aayush Jain et al.

Summary: Phytochemicals show great potential in cancer treatment and can reduce the side-effects of chemotherapy. By interfering with cell signaling pathways, these biologically active compounds effectively inhibit the growth of cancer cells and protect healthy cells from damage.

JOURNAL OF CANCER (2021)

Review Multidisciplinary Sciences

A review of green methods for phyto-fabrication of hematite (α-Fe2O3) nanoparticles and their characterization, properties, and applications

Mostafa F. Al-Hakkani et al.

Summary: This study presents a quick and simple literature survey on the bio-fabrication of Alpha Hematite nanoparticles using plant extracts green method, highlighting the utility of environmentally friendly biosynthesis methods, physicochemical properties, instrumental analysis tools, and potential applications.

HELIYON (2021)

Article Surgery

Photodynamic Therapy for Benign Cutaneous Neurofibromas Using Aminolevulinic Acid Topical Application and 633 nm Red Light Illumination

Brendan Quirk et al.

Summary: Neurofibromatosis type 1 (NF1) currently lacks effective treatments, but topical photodynamic therapy (PDT) shows potential for treating cutaneous neurofibromas with less invasiveness. This study conducted a phase I trial to examine the absorption and safety of topical aminolevulinic acid (ALA) in neurofibromas, demonstrating specific targeting of neurofibromas and potential for future tissue-sparing treatment modalities.

PHOTOBIOMODULATION PHOTOMEDICINE AND LASER SURGERY (2021)

Article Biochemistry & Molecular Biology

Development of pH-Responsive Biopolymeric Nanocapsule for Antibacterial Essential Oils

Sylvie Skalickova et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Review Nanoscience & Nanotechnology

Rational design of block copolymer self-assemblies in photodynamic therapy

Maxime Demazeau et al.

BEILSTEIN JOURNAL OF NANOTECHNOLOGY (2020)

Review Chemistry, Physical

Nanotechnology Scaffolds for Alveolar Bone Regeneration

Goker Funda et al.

MATERIALS (2020)

Article Chemistry, Analytical

Integrated Immunomagnetic Bead-Based Microfluidic Chip for Exosomes Isolation

Fuzhou Niu et al.

MICROMACHINES (2020)

Article Nanoscience & Nanotechnology

Dual-Effect of Magnetic Resonance Imaging Reporter Gene in Diagnosis and Treatment of Hepatocellular Carcinoma

Jiaping Zhou et al.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2020)

Review Medicine, Research & Experimental

Emerging Function and Clinical Significance of Exosomal circRNAs in Cancer

Man Wang et al.

MOLECULAR THERAPY-NUCLEIC ACIDS (2020)

Article Biotechnology & Applied Microbiology

Tumor Exosome Mimicking Nanoparticles for Tumor Combinatorial Chemo-Photothermal Therapy

Ran Tian et al.

FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY (2020)

Review Chemistry, Multidisciplinary

A Review of Carbon Dots Produced from Biomass Wastes

Chao Kang et al.

NANOMATERIALS (2020)

Article Chemistry, Multidisciplinary

Exosomes for Wound Healing: Purification Optimization and Identification of Bioactive Components

Britta F. Hettich et al.

ADVANCED SCIENCE (2020)

Article Materials Science, Biomaterials

Bio-engineered cell membrane nanovesicles as precision theranostics for perihilar cholangiocarcinoma

Xiaojie Zhang et al.

BIOMATERIALS SCIENCE (2020)

Article Biotechnology & Applied Microbiology

A high stable pH-temperature dual-sensitive liposome for tuning anticancer drug release

Yilin Zhao et al.

SYNTHETIC AND SYSTEMS BIOTECHNOLOGY (2020)

Article Biotechnology & Applied Microbiology

Gold nano particles synthesized from Strychni semen and its anticancer activity in cholangiocarcinoma cell (KMCH-1)

Yuehua Li et al.

ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY (2019)

Review Chemistry, Multidisciplinary

Engineering Cell Membrane-Based Nanotherapeutics to Target Inflammation

Huize Yan et al.

ADVANCED SCIENCE (2019)

Article Biochemistry & Molecular Biology

Magnetic Polyurea Nano-Capsules Synthesized via Interfacial Polymerization in Inverse Nano-Emulsion

Suzana Natour et al.

MOLECULES (2019)

Article Chemistry, Medicinal

Solutol® HS15+pluronicF127 and Solutol® HS15+pluronicL61 mixed micelle systems for oral delivery of genistein

Pinggang Ding et al.

DRUG DESIGN DEVELOPMENT AND THERAPY (2019)

Review Nanoscience & Nanotechnology

Advances in nanocarriers as drug delivery systems in Chagas disease

Christian Quijia Quezada et al.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2019)

Article Chemistry, Multidisciplinary

Heat-activated drug delivery increases tumor accumulation of synergistic chemotherapies

Michael Dunne et al.

JOURNAL OF CONTROLLED RELEASE (2019)

Review Biotechnology & Applied Microbiology

Current outlook on radionuclide delivery systems: from design consideration to translation into clinics

Oleksii O. Peltek et al.

JOURNAL OF NANOBIOTECHNOLOGY (2019)

Review Biotechnology & Applied Microbiology

Small molecules derived carbon dots: synthesis and applications in sensing, catalysis, imaging, and biomedicine

Anirudh Sharma et al.

JOURNAL OF NANOBIOTECHNOLOGY (2019)

Review Biochemistry & Molecular Biology

Synthesis, Bioapplications, and Toxicity Evaluation of Chitosan-Based Nanoparticles

Balsam R. Rizeq et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)

Review Nanoscience & Nanotechnology

The Toxicity Of Metallic Nanoparticles On Liver: The Subcellular Damages, Mechanisms, And Outcomes

Ying Yao et al.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2019)

Article Nanoscience & Nanotechnology

A Nanodrug Consisting Of Doxorubicin And Exosome Derived From Mesenchymal Stem Cells For Osteosarcoma Treatment In Vitro

Hongxiang Wei et al.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2019)

Review Oncology

Recent advances in nanotheranostics for triple negative breast cancer treatment

Vikram Thakur et al.

JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2019)

Article Biochemistry & Molecular Biology

Copper Ions Removal from Water using A2B3 Type Hyperbranched Poly(amidoamine) Hydrogel Particles

Hojung Choi et al.

MOLECULES (2019)

Review Chemistry, Multidisciplinary

Extracellular Vesicles in Cancer Immune Microenvironment and Cancer Immunotherapy

Feng Xie et al.

ADVANCED SCIENCE (2019)

Review Biochemistry & Molecular Biology

Harnessing tumor-associated macrophages as aids for cancer immunotherapy

Xiaolei Li et al.

MOLECULAR CANCER (2019)

Article Biochemistry & Molecular Biology

Therapeutic Potential of Polyamidoamine Dendrimer for Amyloidogenic Transthyretin Amyloidosis

Masamichi Inoue et al.

ACS CHEMICAL NEUROSCIENCE (2019)

Article Biotechnology & Applied Microbiology

Preparation of Antimicrobial Hyaluronic Acid/Quaternized Chitosan Hydrogels for the Promotion of Seawater-Immersion Wound Healing

Xinlu Wang et al.

FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY (2019)

Article Pharmacology & Pharmacy

Carbon dots have antitumor action as monotherapy or combination therapy

Jufeng Xia et al.

DRUG DISCOVERIES AND THERAPEUTICS (2019)

Article Biotechnology & Applied Microbiology

Transcriptomic analysis and mutational status of IDH1 in paired primary-recurrent intrahepatic cholangiocarcinoma

C. Peraldo-Neia et al.

BMC GENOMICS (2018)

Article Dermatology

Plasmonic photothermal therapy: Approaches to advanced strategy

Alla B. Bucharskaya et al.

LASERS IN SURGERY AND MEDICINE (2018)

Review Biochemistry & Molecular Biology

Chemical Modification of Chitosan for Efficient Vaccine Delivery

Lei Xing et al.

MOLECULES (2018)

Article Biotechnology & Applied Microbiology

Anticancer activities of epigallocatechin-3-gallate against cholangiocarcinoma cells

Tae Won Kwak et al.

ONCOTARGETS AND THERAPY (2017)

Article Nanoscience & Nanotechnology

Enhanced efficacy of combination heat shock targeted polymer therapeutics with high intensity focused ultrasound

Nick Frazier et al.

NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE (2017)

Review Cell & Tissue Engineering

Nanomaterials for the Capture and Therapeutic Targeting of Circulating Tumor Cells

Zhenjiang Zhang et al.

CELLULAR AND MOLECULAR BIOENGINEERING (2017)

Article Chemistry, Medicinal

Controlling Properties and Cytotoxicity of Chitosan Nanocapsules by Chemical Grafting

Laura De Matteis et al.

MARINE DRUGS (2016)

Article Materials Science, Biomaterials

Targeted delivery of 5-fluorouracil to cholangiocarcinoma cells using folic acid as a targeting agent

Nipaporn Ngernyuang et al.

MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2016)

Review Nanoscience & Nanotechnology

Targeting tumor microenvironment with PEG-based amphiphilic nanoparticles to overcome chemoresistance

Shizhu Chen et al.

NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE (2016)

Article Nanoscience & Nanotechnology

Development of exosome-encapsulated paclitaxel to overcome MDR in cancer cells

Myung Soo Kim et al.

NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE (2016)

Article Multidisciplinary Sciences

Core-shell nanocarriers with high paclitaxel loading for passive and active targeting

Zhu Jin et al.

SCIENTIFIC REPORTS (2016)

Article

Gold Nanoparticles Enhance the Anticancer Activity of Gallic Acid against Cholangiocarcinoma Cell Lines

Narintorn Rattanata et al.

Asian Pacific Journal of Cancer Prevention (2015)

Article Pharmacology & Pharmacy

Stealth Amphotericin B nanoparticles for oral drug delivery: In vitro optimization

Bushra T. AL-Quadeib et al.

SAUDI PHARMACEUTICAL JOURNAL (2015)

Article Biotechnology & Applied Microbiology

Nanotoxic Profiling of Novel Iron Oxide Nanoparticles Functionalized with Perchloric Acid and SiPEG as a Radiographic Contrast Medium

Muhamad Idham Mohamed et al.

BIOMED RESEARCH INTERNATIONAL (2015)

Article Biotechnology & Applied Microbiology

Novel pH-sensitive nanoformulated docetaxel as a potential therapeutic strategy for the treatment of cholangiocarcinoma

Nan Du et al.

JOURNAL OF NANOBIOTECHNOLOGY (2015)

Article Biotechnology & Applied Microbiology

Antitumor activity of vorinostat-incorporated nanoparticles against human cholangiocarcinoma cells

Tae Won Kwak et al.

JOURNAL OF NANOBIOTECHNOLOGY (2015)

Article Pharmacology & Pharmacy

Enhanced hepatoprotective activity of andrographolide complexed with a biomaterial

Amol D. Thingale et al.

DRUG DELIVERY (2015)

Article Chemistry, Multidisciplinary

Effect of 5-Aminolevulinic Acid-Encapsulate Liposomes on Photodynamic Therapy in Human Cholangiocarcinoma Cells

Kyung Ha Choi et al.

JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY (2014)

Article Multidisciplinary Sciences

Development and Characterization of Nanoparticles for the Delivery of Gemcitabine Hydrochloride

Rekha Khaira et al.

SCIENTIFIC WORLD JOURNAL (2014)

Article Radiology, Nuclear Medicine & Medical Imaging

In vivo bioluminescence imaging for viable human neural stem cells incorporated within in situ gelatin hydrogels

Do Won Hwang et al.

EJNMMI RESEARCH (2014)

Article Nanoscience & Nanotechnology

Preclinical evaluation of sorafenib-eluting stent for suppression of human cholangiocarcinoma cells

Do Hyung Kim et al.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2013)

Article Pharmacology & Pharmacy

Ursodeoxycholic acid-conjugated chitosan for photodynamic treatment of HuCC-T1 human cholangiocarcinoma cells

Hye Myeong Lee et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2013)

Article Oncology

Photosan-II loaded hollow silica nanoparticles: Preparation and its effect in killing for QBC939 cells

Xiaofeng Deng et al.

PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY (2013)

Review Chemistry, Multidisciplinary

Cancer detection using nanoparticle-based sensors

Maelle Perfezou et al.

CHEMICAL SOCIETY REVIEWS (2012)

Article Biochemistry & Molecular Biology

Biocompatible Drug Delivery System for Photo-Triggered Controlled Release of 5-Fluorouracil

Qiao Jin et al.

BIOMACROMOLECULES (2011)

Article Biochemical Research Methods

Tumor Targeting Chitosan Nanoparticles for Dual-Modality Optical/MR Cancer Imaging

Taehwan Nam et al.

BIOCONJUGATE CHEMISTRY (2010)

Review Nanoscience & Nanotechnology

Viral nanoparticles as platforms for next-generation therapeutics and imaging devices

Nicole F. Steinmetz

NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE (2010)

Article Multidisciplinary Sciences

Targeting the IL-6 Dependent Phenotype Can Identify Novel Therapies for Cholangiocarcinoma

Chiara Braconi et al.

PLOS ONE (2010)

Review Reproductive Biology

Scope of nanotechnology in ovarian cancer therapeutics

Murali M. Yallapu et al.

JOURNAL OF OVARIAN RESEARCH (2010)

Article Engineering, Biomedical

The control of dendritic cell maturation by pH-sensitive polyion complex micelles

Ariane Boudier et al.

BIOMATERIALS (2009)

Review Biochemistry & Molecular Biology

Multiscale Modeling of Dendrimers and Their Interactions with Bilayers and Polyelectrolytes

Hwankyu Lee et al.

MOLECULES (2009)

Article Chemistry, Multidisciplinary

Drug-loaded superparamagnetic iron oxide nanoparticles for combined cancer imaging and therapy in vivo

Mi Kyung Yu et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2008)

Article Pharmacology & Pharmacy

Pharmacokinetics and urinary excretion of vincristine sulfate liposomes injection in metastatic melanoma patients

Agop Y. Bedikian et al.

JOURNAL OF CLINICAL PHARMACOLOGY (2006)