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Alamandine attenuates hypertension and cardiac hypertrophy in hypertensive rats
Chi Liu et al.
AMINO ACIDS (2018)
Salt, Hypertension, and Immunity
A. Justin Rucker et al.
ANNUAL REVIEW OF PHYSIOLOGY, VOL 80 (2018)
Hypertension and increased endothelial mechanical stretch promote monocyte differentiation and activation: roles of STAT3, interleukin 6 and hydrogen peroxide
Roxana Loperena et al.
CARDIOVASCULAR RESEARCH (2018)
Decarboxylation of Ang-(1-7) to Ala1-Ang-(1-7) leads to significant changes in pharmacodynamics
Anja Tetzner et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2018)
A potential therapeutic role for angiotensin-converting enzyme 2 in human pulmonary arterial hypertension
Anna R. Hemnes et al.
EUROPEAN RESPIRATORY JOURNAL (2018)
Novel ACE2-Fc chimeric fusion provides long-lasting hypertension control and organ protection in mouse models of systemic renin angiotensin system activation
Pan Liu et al.
KIDNEY INTERNATIONAL (2018)
Alamandine attenuates sepsis-associated cardiac dysfunction via inhibiting MAPKs signaling pathways
Peng Li et al.
LIFE SCIENCES (2018)
Alamandine injected into the paraventricular nucleus increases blood pressure and sympathetic activation in spontaneously hypertensive rats
Yi-Hui Shen et al.
PEPTIDES (2018)
ANGIOTENSIN II SIGNAL TRANSDUCTION: AN UPDATE ON MECHANISMS OF PHYSIOLOGY AND PATHOPHYSIOLOGY
Steven J. Forrester et al.
PHYSIOLOGICAL REVIEWS (2018)
THE ACE2/ANGIOTENSIN-(1-7)/MAS AXIS OF THE RENIN-ANGIOTENSIN SYSTEM: FOCUS ON ANGIOTENSIN-(1-7)
Robson Augusto Souza Santos et al.
PHYSIOLOGICAL REVIEWS (2018)
Elevated plasma angiotensin converting enzyme 2 activity is an independent predictor of major adverse cardiac events in patients with obstructive coronary artery disease
Jay Ramchand et al.
PLOS ONE (2018)
Angiotensin-(1-9) reduces cardiovascular and renal inflammation in experimental renin-independent hypertension
Leticia Gonzalez et al.
BIOCHEMICAL PHARMACOLOGY (2018)
Protection of the myocardium against ischemia/reperfusion injury by angiotensin-(1-9) through an AT2R and Akt-dependent mechanism
Evelyn Mendoza-Torres et al.
PHARMACOLOGICAL RESEARCH (2018)
Association of ACE2 polymorphisms with susceptibility to essential hypertension and dyslipidemia in Xinjiang, China
Yizhi Pan et al.
LIPIDS IN HEALTH AND DISEASE (2018)
Hypertension-Linked Pathophysiological Alterations in the Gut
Monica M. Santisteban et al.
CIRCULATION RESEARCH (2017)
Evidence for Heterodimerization and Functional Interaction of the Angiotensin Type 2 Receptor and the Receptor MAS
Julia Leonhardt et al.
HYPERTENSION (2017)
Structural basis for selectivity and diversity in angiotensin II receptors
Haitao Zhang et al.
NATURE (2017)
Hypotensive effect induced by microinjection of Alamandine, a derivative of angiotensin-(1-7), into caudal ventrolateral medulla of 2K1C hypertensive rats
E. R. Soares et al.
PEPTIDES (2017)
AT2 receptors in cardiovascular and renal diseases
Elena Kaschina et al.
PHARMACOLOGICAL RESEARCH (2017)
Gut microbiota dysbiosis contributes to the development of hypertension
Jing Li et al.
MICROBIOME (2017)
Alamandine reduces leptin expression through the c-Src/p38 MAP kinase pathway in adipose tissue
Tsuyoshi Uchiyama et al.
PLOS ONE (2017)
Anti-atherosclerotic effect of the angiotensin 1-7 mimetic AVE0991 is mediated by inhibition of perivascular and plaque inflammation in early atherosclerosis
D. S. Skiba et al.
BRITISH JOURNAL OF PHARMACOLOGY (2017)
Alamandine reverses hyperhomocysteinemia-induced vascular dysfunction via PKA-dependent mechanisms
Tawar Qaradakhi et al.
CARDIOVASCULAR THERAPEUTICS (2017)
A pilot clinical trial of recombinant human angiotensin-converting enzyme 2 in acute respiratory distress syndrome
Akram Khan et al.
CRITICAL CARE (2017)
AT2 Receptor Activation Prevents Sodium Retention and Reduces Blood Pressure in Angiotensin II- Dependent Hypertension
Brandon A. Kemp et al.
CIRCULATION RESEARCH (2016)
Angiotensin Type-2 Receptors Influence the Activity of Vasopressin Neurons in the Paraventricular Nucleus of the Hypothalamus in Male Mice
Annette D. de Kloet et al.
ENDOCRINOLOGY (2016)
Therapeutic uses for Angiotensin-(1-7)
Alice Machado-Silva et al.
EXPERT OPINION ON THERAPEUTIC PATENTS (2016)
Activation of Human T Cells in Hypertension Studies of Humanized Mice and Hypertensive Humans
Hana A. Itani et al.
HYPERTENSION (2016)
G-Protein-Coupled Receptor MrgD Is a Receptor for Angiotensin-(1-7) Involving Adenylyl Cyclase, cAMP, and Phosphokinase A
Anja Tetzner et al.
HYPERTENSION (2016)
Renal hemodynamics and renin-angiotensin system activity in humans with multifocal renal artery fibromuscular dysplasia
Daan J. L. van Twist et al.
JOURNAL OF HYPERTENSION (2016)
Gene Therapy With Angiotensin-(1-9) Preserves Left Ventricular Systolic Function After Myocardial Infarction
Caroline Fattah et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2016)
Association between circulating levels of ACE2-Ang-(1-7)-MAS axis and ACE2 gene polymorphisms in hypertensive patients
Dan Liu et al.
MEDICINE (2016)
Central Infusion of Angiotensin II Type 2 Receptor Agonist Compound 21 Attenuates DOCA/NaCl-Induced Hypertension in Female Rats
Shu-Yan Dai et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2016)
Angiotensin (1-7) and Alamandine: Similarities and differences
Tawar Qaradakhi et al.
PHARMACOLOGICAL RESEARCH (2016)
Upregulation of Angiotensin (1-7)-Mediated Signaling Preserves Endothelial Function Through Reducing Oxidative Stress in Diabetes
Yang Zhang et al.
ANTIOXIDANTS & REDOX SIGNALING (2015)
Gut Dysbiosis Is Linked to Hypertension
Tao Yang et al.
HYPERTENSION (2015)
Angiotensin-(1-7) enhances the effects of angiotensin II on the cardiac sympathetic afferent reflex and sympathetic activity in rostral ventrolateral medulla in renovascular hypertensive rats
Peng Li et al.
JOURNAL OF THE AMERICAN SOCIETY OF HYPERTENSION (2015)
Angiotensin-(1-7) Prevents Angiotensin II-induced Fibrosis in Cremaster Microvessels
Kyle A. Carver et al.
MICROCIRCULATION (2015)
Activation of angiotensin-(1-7)/Mas axis in the brain lowers blood pressure and attenuates cardiac remodeling in hypertensive transgenic (mRen2)27 rats
Lucas M. Kangussu et al.
NEUROPHARMACOLOGY (2015)
Association of angiotensin-converting enzyme and angiotensin-converting enzyme-2 gene polymorphisms with essential hypertension in the population of Odisha, India
Manisha Patnaik et al.
ANNALS OF HUMAN BIOLOGY (2014)
Angiotensin-(1-7) attenuates angiotensin II-induced signalling associated with activation of a tyrosine phosphatase in Sprague-Dawley rats cardiac fibroblasts
Xiaoling Tao et al.
BIOLOGY OF THE CELL (2014)
Deletion of angiotensin-converting enzyme 2 promotes the development of atherosclerosis and arterial neointima formation
Makoto Sahara et al.
CARDIOVASCULAR RESEARCH (2014)
New Components of the Renin-Angiotensin System: Alamandine and the Mas-Related G Protein-Coupled Receptor D
Gisele Maia Etelvino et al.
CURRENT HYPERTENSION REPORTS (2014)
Increasing Angiotensin-(1-7) Levels in the Brain Attenuates Metabolic Syndrome-Related Risks in Fructose-Fed Rats
Priscila S. Guimaraes et al.
HYPERTENSION (2014)
Angiotensin-Converting Enzyme 2-Independent Action of Presumed Angiotensin-Converting Enzyme 2 Activators Studies In Vivo, Ex Vivo, and In Vitro
Philipp K. Haber et al.
HYPERTENSION (2014)
Reduction of angiotensin A and alamandine vasoactivity in the rabbit model of atherogenesis: differential effects of alamandine and Ang(1-7)
Belthrand Habiyakare et al.
INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY (2014)
Angiotensin-(1-7)-induced renal vasodilation is reduced in human kidneys with renal artery stenosis
Daan J. L. Van Twist et al.
JOURNAL OF HYPERTENSION (2014)
Angiotensin-(1-9) reverses experimental hypertension and cardiovascular damage by inhibition of the angiotensin converting enzyme/Ang II axis
Maria Paz Ocaranza et al.
JOURNAL OF HYPERTENSION (2014)
Angiotensin-converting enzyme 2 and angiotensin 1-7: novel therapeutic targets
Fan Jiang et al.
NATURE REVIEWS CARDIOLOGY (2014)
Autoimmunity in the pathogenesis of hypertension
Bernardo Rodriguez-Iturbe et al.
NATURE REVIEWS NEPHROLOGY (2014)
New Perspectives in the Renin-Angiotensin-Aldosterone System (RAAS) IV: Circulating ACE2 as a Biomarker of Systolic Dysfunction in Human Hypertension and Heart Failure
Katalin Uri et al.
PLOS ONE (2014)
Vascular effects of a tripeptide fragment of novokinine in hypertensive rats: Mechanism of the hypotensive action
Bozena Badzynska et al.
PHARMACOLOGICAL REPORTS (2014)
From gene to protein-experimental and clinical studies of ACE2 in blood pressure control and arterial hypertension
Sheila K. Patel et al.
FRONTIERS IN PHYSIOLOGY (2014)
Effects of enalapril on the expression of cardiac angiotensin-converting enzyme and angiotensin-converting enzyme 2 in spontaneously hypertensive rats
Zhen Yang et al.
ARCHIVES OF CARDIOVASCULAR DISEASES (2013)
Angiotensin 1-7 and Mas decrease thrombosis in Bdkrb2-/- mice by increasing NO and prostacyclin to reduce platelet spreading and glycoprotein VI activation
Chao Fang et al.
BLOOD (2013)
Brain Angiotensin-Converting Enzyme Type 2 Shedding Contributes to the Development of Neurogenic Hypertension
Huijing Xia et al.
CIRCULATION RESEARCH (2013)
Discovery and Characterization of Alamandine A Novel Component of the Renin-Angiotensin System
Roberto Queiroga Lautner et al.
CIRCULATION RESEARCH (2013)
Pharmacokinetics and Pharmacodynamics of Recombinant Human Angiotensin-Converting Enzyme 2 in Healthy Human Subjects
Manuel Haschke et al.
CLINICAL PHARMACOKINETICS (2013)
Angiotensin-converting enzyme 2 antagonizes angiotensin II-induced pressor response and NADPH oxidase activation in Wistar-Kyoto rats and spontaneously hypertensive rats
Jennifer Lo et al.
EXPERIMENTAL PHYSIOLOGY (2013)
Immunosenescent CD8+ T Cells and C-X-C Chemokine Receptor Type 3 Chemokines Are Increased in Human Hypertension
Jong-Chan Youn et al.
HYPERTENSION (2013)
Angiotensin-Converting Enzyme 2 Priming Enhances the Function of Endothelial Progenitor Cells and Their Therapeutic Efficacy
Ji Chen et al.
HYPERTENSION (2013)
Angiotensin-(1-7)-Induced Renal Vasodilation in Hypertensive Humans Is Attenuated by Low Sodium Intake and Angiotensin II Co-Infusion
Daan J. L. van Twist et al.
HYPERTENSION (2013)
Functional Cross-Talk Between Aldosterone and Angiotensin-(1-7) in Ventricular Myocytes
Pedro W. Machado de Almeida et al.
HYPERTENSION (2013)
Angiotensin II Type 2 Receptor-Mediated and Nitric Oxide-Dependent Renal Vasodilator Response to Compound 21 Unmasked by Angiotensin-Converting Enzyme Inhibition in Spontaneously Hypertensive Rats In Vivo
Sofie Brouwers et al.
HYPERTENSION (2013)
Newly Discovered Components and Actions of the Renin-Angiotensin System
Robert M. Carey
HYPERTENSION (2013)
Diminazene Aceturate Enhances Angiotensin-Converting Enzyme 2 Activity and Attenuates Ischemia-Induced Cardiac Pathophysiology
YanFei Qi et al.
HYPERTENSION (2013)
Angiotensin-Converting Enzyme 2 Activation Improves Endothelial Function
Rodrigo A. Fraga-Silva et al.
HYPERTENSION (2013)
Increasing Serum Soluble Angiotensin-Converting Enzyme 2 Activity After Intensive Medical Therapy Is Associated With Better Prognosis in Acute Decompensated Heart Failure
Zhili Shao et al.
JOURNAL OF CARDIAC FAILURE (2013)
Complete blockade of the vasorelaxant effects of angiotensin-(17) and bradykinin in murine microvessels by antagonists of the receptor Mas
Concepcion Peiro et al.
JOURNAL OF PHYSIOLOGY-LONDON (2013)
Chronic AT2 receptor activation increases renal ACE2 activity, attenuates AT1 receptor function and blood pressure in obese Zucker rats
Quaisar Ali et al.
KIDNEY INTERNATIONAL (2013)
Stimulation of ANP by angiotensin-(1-9) via the angiotensin type 2 receptor
Seung Ah Cha et al.
LIFE SCIENCES (2013)
Molecular basis of binding between novel human coronavirus MERS-CoV and its receptor CD26
Guangwen Lu et al.
NATURE (2013)
Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC
V. Stalin Raj et al.
NATURE (2013)
Emerging Role of Angiotensin Type 2 Receptor (AT2R)/Akt/NO Pathway in Vascular Smooth Muscle Cell in the Hyperthyroidism
Maria Alicia Carrillo-Sepulveda et al.
PLOS ONE (2013)
The Effects of Angiotensin II and Angiotensin-(1-7) in the Rostral Ventrolateral Medulla of Rats on Stress-Induced Hypertension
Dongshu Du et al.
PLOS ONE (2013)
Angiotensin-(1-7) inhibits vascular calcification in rats
Yu-Bin Sui et al.
PEPTIDES (2013)
Angiotensin AT2 receptor agonist stimulates high stretch induced-ANP secretion via PI3K/NO/sGC/PKG/pathway
Shan Gao et al.
PEPTIDES (2013)
Angiotensin-(1-7) upregulates central nitric oxide synthase in spontaneously hypertensive rats
Bruno D. Cerrato et al.
BRAIN RESEARCH (2012)
Murine Recombinant Angiotensin-Converting Enzyme 2 Effect on Angiotensin II-Dependent Hypertension and Distinctive Angiotensin-Converting Enzyme 2 Inhibitor Characteristics on Rodent and Human Angiotensin-Converting Enzyme 2
Minghao Ye et al.
HYPERTENSION (2012)
Angiotensin-(1-9) Attenuates Cardiac Fibrosis in the Stroke-Prone Spontaneously Hypertensive Rat via the Angiotensin Type 2 Receptor
Monica Flores-Munoz et al.
HYPERTENSION (2012)
Compound 21 Induces Vasorelaxation via an Endothelium- and Angiotensin II Type 2 Receptor-Independent Mechanism
Koen Verdonk et al.
HYPERTENSION (2012)
Identification of Physiologically Active Substances as Novel Ligands for MRGPRD
Makiko Uno et al.
JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY (2012)
Circulating ACE2 activity is increased in patients with type 1 diabetes and vascular complications
Aino Soro-Paavonen et al.
JOURNAL OF HYPERTENSION (2012)
Nebivolol reduces cardiac angiotensin II, associated oxidative stress and fibrosis but not arterial pressure in salt-loaded spontaneously hypertensive rats
Jasmina Varagic et al.
JOURNAL OF HYPERTENSION (2012)
Angiotensin converting enzyme 2 abrogates bleomycin-induced lung injury
G. J. Rey-Parra et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2012)
Angiotensin-(1-7) through Mas receptor up-regulates neuronal norepinephrine transporter via Akt and Erk1/2-dependent pathways
Maria A. Lopez Verrilli et al.
JOURNAL OF NEUROCHEMISTRY (2012)
Time-Resolved Quantitative Phosphoproteomics: New Insights into Angiotensin-(1-7) Signaling Networks in Human Endothelial Cells
Thiago Verano-Braga et al.
JOURNAL OF PROTEOME RESEARCH (2012)
ACE2 gene polymorphism and essential hypertension: an updated meta-analysis involving 11,051 subjects
Na Lu et al.
MOLECULAR BIOLOGY REPORTS (2012)
ACE2 links amino acid malnutrition to microbial ecology and intestinal inflammation
Tatsuo Hashimoto et al.
NATURE (2012)
Adenoviral Delivery of Angiotensin-(1-7) or Angiotensin-(1-9) Inhibits Cardiomyocyte Hypertrophy via the Mas or Angiotensin Type 2 Receptor
Monica Flores-Munoz et al.
PLOS ONE (2012)
Angiotensin-(1-7) abrogates mitogen-stimulated proliferation of cardiac fibroblasts
LaTronya T. McCollum et al.
PEPTIDES (2012)
The Effect of the Thioether-Bridged, Stabilized Angiotensin-(1-7) Analogue Cyclic Ang-(1-7) on Cardiac Remodeling and Endothelial Function in Rats with Myocardial Infarction
Matej Durik et al.
INTERNATIONAL JOURNAL OF HYPERTENSION (2012)
Regulation of alveolar epithelial cell survival by the ACE-2/angiotensin 1-7/Mas axis
Bruce D. Uhal et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2011)
Species-specific inhibitor sensitivity of angiotensin-converting enzyme 2 (ACE2) and its implication for ACE2 activity assays
Kim Brint Pedersen et al.
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2011)
ACE2 overexpression in the paraventricular nucleus attenuates angiotensin II-induced hypertension
Srinivas Sriramula et al.
CARDIOVASCULAR RESEARCH (2011)
Role of Angiotensin-(1-7) in Rostral Ventrolateral Medulla in Blood Pressure Regulation via Sympathetic Nerve Activity in Wistar-Kyoto and Spontaneous Hypertensive Rats
Toshiaki Nakagaki et al.
CLINICAL AND EXPERIMENTAL HYPERTENSION (2011)
Angiotensin-(1-7) infusion is associated with increased blood pressure and adverse cardiac remodelling in rats with subtotal nephrectomy
Elena Velkoska et al.
CLINICAL SCIENCE (2011)
An orally active formulation of angiotensin-(1-7) produces an antithrombotic effect
Rodrigo Araujo Fraga-Silva et al.
CLINICS (2011)
Angiotensin-converting enzyme 2 activation protects against hypertension-induced cardiac fibrosis involving extracellular signal-regulated kinases
Anderson J. Ferreira et al.
EXPERIMENTAL PHYSIOLOGY (2011)
A Single β-Amino Acid Substitution to Angiotensin II Confers AT2 Receptor Selectivity and Vascular Function
Emma S. Jones et al.
HYPERTENSION (2011)
An Oral Formulation of Angiotensin-(1-7) Produces Cardioprotective Effects in Infarcted and Isoproterenol-Treated Rats
Fulvia D. Marques et al.
HYPERTENSION (2011)
Regulation of angiotensin-converting enzyme 2 and Mas receptor by Ang-(1-7) in heart and kidney of spontaneously hypertensive rats
Zhen Tan et al.
JOURNAL OF THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM (2011)
Inhibition of Angiotensin-Converting Enzyme 2 Exacerbates Cardiac Hypertrophy and Fibrosis in Ren-2 Hypertensive Rats
Aaron J. Trask et al.
AMERICAN JOURNAL OF HYPERTENSION (2010)
Vascular wall ACE is not required for atherogenesis in ApoE(-/-) mice
Daiana Weiss et al.
ATHEROSCLEROSIS (2010)
Angiotensin-Converting Enzyme 2 Suppresses Pathological Hypertrophy, Myocardial Fibrosis, and Cardiac Dysfunction
JiuChang Zhong et al.
CIRCULATION (2010)
Genetic Ace2 Deficiency Accentuates Vascular Inflammation and Atherosclerosis in the ApoE Knockout Mouse
Merlin C. Thomas et al.
CIRCULATION RESEARCH (2010)
Human Recombinant ACE2 Reduces the Progression of Diabetic Nephropathy
Gavin Y. Oudit et al.
DIABETES (2010)
The nonpeptide AVE0991 attenuates myocardial hypertrophy as induced by angiotensin II through downregulation of transforming growth factor-β1/Smad2 expression
Jian-Gui He et al.
HEART AND VESSELS (2010)
Targeting the Degradation of Angiotensin II With Recombinant Angiotensin-Converting Enzyme 2 Prevention of Angiotensin II-Dependent Hypertension
Jan Wysocki et al.
HYPERTENSION (2010)
Vascular Relaxation, Antihypertensive Effect, and Cardioprotection of a Novel Peptide Agonist of the Mas Receptor
Silvia Quintao Savergnini et al.
HYPERTENSION (2010)
Lifetime Overproduction of Circulating Angiotensin-(1-7) Attenuates Deoxycorticosterone Acetate-Salt Hypertension-Induced Cardiac Dysfunction and Remodeling
Nivia M. Santiago et al.
HYPERTENSION (2010)
Angiotensin-(1-7) Prevents Cardiomyocyte Pathological Remodeling Through a Nitric Oxide/Guanosine 3 ',5 '-Cyclic Monophosphate-Dependent Pathway
Eneas R. M. Gomes et al.
HYPERTENSION (2010)
Angiotensin-(1-9) regulates cardiac hypertrophy in vivo and in vitro
Maria Paz Ocaranza et al.
JOURNAL OF HYPERTENSION (2010)
ACE2 Activation Promotes Antithrombotic Activity
Rodrigo A. Fraga-Silva et al.
MOLECULAR MEDICINE (2010)
Angiotensin II Type 1 Receptor-Mediated Reduction of Angiotensin-Converting Enzyme 2 Activity in the Brain Impairs Baroreflex Function in Hypertensive Mice
Huijing Xia et al.
HYPERTENSION (2009)
Soluble Angiotensin-Converting Enzyme 2 in Human Heart Failure: Relation With Myocardial Function and Clinical Outcomes
Slava Epelman et al.
JOURNAL OF CARDIAC FAILURE (2009)
Impairment of the angiotensin-converting enzyme 2-angiotensin-(1-7)-Mas axis contributes to the acceleration of two-kidney, one-clip Goldblatt hypertension
Marcela Buergelova et al.
JOURNAL OF HYPERTENSION (2009)
Angiotensin-(1-7) through AT2 receptors mediates tyrosine hydroxylase degradation via the ubiquitin-proteasome pathway
Maria A. Lopez Verrilli et al.
JOURNAL OF NEUROCHEMISTRY (2009)
Overexpression of ACE2 enhances plaque stability in a rabbit model of atherosclerosis
Bo Dong et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2008)
Over-expression of anglotensin II type 2 receptor (agtr2) reduces atherogenesis and modulates LOX-1, endothelial nitric oxide synthase and heme-oxygenase-1 expression
Changping Hu et al.
ATHEROSCLEROSIS (2008)
The discovery of angiotensin-converting enzyme 2 and its role in acute lung injury in mice
Yumiko Imai et al.
EXPERIMENTAL PHYSIOLOGY (2008)
Transgenic Angiotensin-Converting Enzyme 2 Overexpression in Vessels of SHRSP Rats Reduces Blood Pressure and Improves Endothelial Function
Brit Rentzsch et al.
HYPERTENSION (2008)
Conversion of renal angiotensin II to angiotensin III is critical for AT2 receptor-mediated natriuresis in rats
Shetal H. Padia et al.
HYPERTENSION (2008)
Endothelial dysfunction and elevated blood pressure in Mas gene-deleted mice
Ping Xu et al.
HYPERTENSION (2008)
Molecular mechanisms involved in the angiotensin-(1-7)/Mas signaling pathway in cardiomyocytes
Marco F. Dias-Peixoto et al.
HYPERTENSION (2008)
Early blood pressure-independent cardiac changes in diabetic rats
Daniel Landau et al.
JOURNAL OF ENDOCRINOLOGY (2008)
Detection of soluble angiotensin-converting enzyme 2 in heart failure
Slava Epelman et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2008)
Ablation of angiotensin (1-7) receptor Mas in C57B1/6 mice causes endothelial dysfunction
Luiza A. Rabelo et al.
JOURNAL OF THE AMERICAN SOCIETY OF HYPERTENSION (2008)
Angiotensin metabolites can stimulate receptors of the Mas-related genes family
Florian Gembardt et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2008)
The antithrombotic effect of angiotensin-(1-7) involves mas-mediated NO release from platelets
Rodrigo Araujo Fraga-Silva et al.
MOLECULAR MEDICINE (2008)
Hypotensive activity of novokinin, a potent analogue of ovokinin(2-7), is mediated by angiotensin AT2 receptor and prostaglandin IP receptor
Yuko Yamada et al.
PEPTIDES (2008)
Polymorphisms of angiotensin-converting enzyme 2 gene associated with magnitude of left ventricular hypertrophy in male patients with hypertrophic cardiomyopathy
Wang Shu-Xia et al.
CHINESE MEDICAL JOURNAL (2008)
Correlation of angiotensin-converting enzyme 2 gene polymorphisms with stage 2 hypertension in Han Chinese
Wenquan Niu et al.
TRANSLATIONAL RESEARCH (2007)
Evidence for mas-mediated bradykinin potentiation by the angiotensin-(1-7) nonpeptide mimic AVE 0991 in normotensive rats
Mariana B. L. Carvalho et al.
HYPERTENSION (2007)
ACE2 inhibition worsens glomerular injury in association with increased ACE expression in streptozotocin-induced diabetic mice
M. J. Soler et al.
KIDNEY INTERNATIONAL (2007)
Impaired heart Contractility in apelin gene-deficient mice associated with aging and pressure overload
Keiji Kuba et al.
CIRCULATION RESEARCH (2007)
Functional rescue of a defective angiotensin II AT1 receptor mutant by the Mas protooncogene
Edson L. Santos et al.
REGULATORY PEPTIDES (2007)
Overexpression of angiotensin-converting enzyme 2 in the rostral ventrolateral medulla causes long-term decrease in blood pressure in the spontaneously hypertensive rats
Masanobu Yamazato et al.
HYPERTENSION (2007)
Mass-spectrometric identification of a novel angiotensin peptide in human plasma
Vera Jankowski et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2007)
Renal angiotensin-II receptors expression changes in a model of preeclampsia
Liliana Anguiano-Robledo et al.
HYPERTENSION IN PREGNANCY (2007)
Angiotensin II cell signaling: physiological and pathological effects in the cardiovascular system
Puja K. Mehta et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2007)
Differential expression of neuronal ACE2 in transgenic mice with overexpression of the brain renin-angiotensin system
Marc F. Doobay et al.
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2007)
Angiotensin-(1-7) through receptor Mas mediates endothelial nitric oxide synthase activation via Akt-dependent pathways
Walkyria Oliveira Sampaio et al.
HYPERTENSION (2007)
Angiotensin-(1-7): Pharmacology and new perspectives in cardiovascular treatments
Aaron J. Trask et al.
CARDIOVASCULAR DRUG REVIEWS (2007)
Association study of angiotensin-converting enzyme 2 gene (ACE2) polymorphisms and essential hypertension in northern Han Chinese
W. Huang et al.
JOURNAL OF HUMAN HYPERTENSION (2006)
Angiotensin II stimulates endothelial NO synthase phosphorylation in thoracic aorta of mice with abdominal aortic banding via type 2 receptor
Katsutoshi Yayama et al.
HYPERTENSION (2006)
Circulating activities of angiotensin-converting enzyme, its homolog, angiotensin-converting enzyme 2, and neprilysin in a family study
Gillian I. Rice et al.
HYPERTENSION (2006)
ACE2 gene transfer attenuates hypertension-linked pathophysiological changes in the SHR
Carlos Diez-Freire et al.
PHYSIOLOGICAL GENOMICS (2006)
Angiotensin II type 2 receptor-bradykinin B2 receptor functional heterodimerization
Peter M. Abadir et al.
HYPERTENSION (2006)
Developmental expression of ACE2 in the SHR kidney: A role in hypertension?
C. Tikellis et al.
KIDNEY INTERNATIONAL (2006)
Physiology of local renin-angiotensin systems
Martin Paul et al.
PHYSIOLOGICAL REVIEWS (2006)
A place in our hearts for the lowly angiotensin 1-7 peptide?
TL Reudelhuber
HYPERTENSION (2006)
Deletion of angiotensin-converting enzyme 2 accelerates pressure overload-induced cardiac dysfunction by increasing local angiotensin II
K Yamamoto et al.
HYPERTENSION (2006)
Association of angiotensin-converting enzyme 2 gene A/G polymorphism and elevated blood pressure in Chinese patients with metabolic syndrome
J Zhong et al.
JOURNAL OF LABORATORY AND CLINICAL MEDICINE (2006)
The endothelium-dependent vasodilator effect of the nonpeptide Ang(1-7) mimic AVE 0991 is abolished in the aorta of Mas-knockout mice
VS Lemos et al.
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY (2005)
Effect of angiotensin-converting enzyme inhibition and angiotensin II receptor blockers on cardiac angiotensin-converting enzyme 2
CM Ferrario et al.
CIRCULATION (2005)
Negative regulation of RhoA/Rho kinase by angiotensin II type 2 receptor in vascular smooth muscle cells: role in angiotensin II-induced vasodilation in stroke-prone spontaneously hypertensive rats
C Savoia et al.
JOURNAL OF HYPERTENSION (2005)
Angiotensin type 2 receptor-mediated phosphorylation of eNOS in the aortas of mice with 2-kidney, 1-clip hypertension
H Hiyoshi et al.
HYPERTENSION (2005)
G-protein-coupled receptor Mas is a physiological antagonist of the angiotensin II type 1 receptor
E Kostenis et al.
CIRCULATION (2005)
Global burden of hypertension: analysis of worldwide data
PM Kearney et al.
LANCET (2005)
Upregulation of angiotensin-converting enzyme 2 by all-trans retinoic acid in spontaneously hypertensive rats
JC Zhong et al.
HYPERTENSION (2004)
No association of angiotensin-converting enzyme 2 gene (ACE2) polymorphisms with essential hypertension
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BRITISH JOURNAL OF PHARMACOLOGY (2004)
Design, synthesis, and biological evaluation of the first selective nonpeptide AT2 receptor agonist
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Angiotensin-(1-7) inhibitory mechanism of norepinephrine release in hypertensive rats
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Identification of a G protein-coupled receptor specifically responsive to β-alanine
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Evaluation of angiotensin-converting enzyme (ACE), its homologue ACE2 and neprilysin in angiotensin peptide metabolism
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BIOCHEMICAL JOURNAL (2004)
A novel angiotensin II type 2 receptor signaling pathway: possible role in cardiac hypertrophy
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EMBO JOURNAL (2003)
Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus
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NATURE (2003)
Molecular mechanisms of inhibition of vascular growth by angiotensin-(1-7)
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Characterization of a new selective antagonist for angiotensin-(1-7), D-Pro7-angiotensin-(1-7)
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Effects of truncated angiotensins in humans after double blockade of the renin system
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AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2003)
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JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2002)
Angiotensin-converting enzyme 2 is an essential regulator of heart function
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NATURE (2002)
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HYPERTENSION (2002)
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BRITISH JOURNAL OF PHARMACOLOGY (2002)
A-779 attenuates angiotensin-(1-7) depressor response in salt-induced hypertensive rats
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HYPERTENSION (2001)
Angiotensin(1-7) potentiates bradykinin-induced vasodilatation in man
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JOURNAL OF HYPERTENSION (2001)
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JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
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HYPERTENSION (2001)
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Baroreflex improvement in SHR after ACE inhibition involves angiotensin-(1-7)
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HYPERTENSION (2001)
Angiotensin-(1-7) does not affect vasodilator or TPA responses to bradykinin in human forearm
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HYPERTENSION (2001)
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Angiotensin-(1-7) causes endothelium-dependent relaxation in canine middle cerebral artery
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Angiotensin-(1-7) reduces norepinephrine release through a nitric oxide mechanism in rat hypothalamus
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HYPERTENSION (2000)
Angiotensin-(1-7) attenuates vasoconstriction evoked by angiotensin II but not by noradrenaline in man
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HYPERTENSION (2000)
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