4.4 Article

Construction of lncRNA TYMSOS/hsa-miR-101-3p/CEP55 and TYMSOS/hsa-miR-195-5p/CHEK1 Axis in Non-small Cell Lung Cancer

Related references

Note: Only part of the references are listed.
Article Oncology

Cancer statistics, 2022

Rebecca L. Siegel et al.

Summary: Each year, the American Cancer Society compiles data on cancer occurrence and outcomes in the United States. The latest data shows that breast and prostate cancer progress has stagnated, while lung cancer has shown improvements in survival rates. Lung cancer incidence for advanced disease has declined while localized-stage rates have increased, resulting in higher survival rates. Mortality patterns align with incidence trends, with lung cancer deaths declining rapidly, breast cancer deaths slowing, and prostate cancer deaths stabilizing.

CA-A CANCER JOURNAL FOR CLINICIANS (2022)

Article Biochemistry & Molecular Biology

Ensembl 2022

Fiona Cunningham et al.

Summary: Ensembl is unique in its flexible infrastructure for access to genomic data and annotation. They have focused on expediting annotation of new assemblies via the Ensembl Rapid Release platform, with the greatest annual number of newly annotated genomes released. They also developed a new method for comparative analyses and annotated non-vertebrate eukaryotes for the first time.

NUCLEIC ACIDS RESEARCH (2022)

Article Biochemistry & Molecular Biology

FOXM1/lncRNA TYMSOS/miR-214-3p-Mediated High Expression of NCAPG Correlates With Poor Prognosis and Cell Proliferation in Non-Small Cell Lung Carcinoma

Yixiao Yuan et al.

Summary: This study found that NCAPG is highly expressed in various human cancers, especially in NSCLC. NCAPG expression is significantly correlated with poor clinical-pathological features, poor prognosis, tumor mutational burden, DNA microsatellite instability, and immune cell infiltration in NSCLC. Additionally, NCAPG and other related molecules (such as miRNA-214-3p and lncRNA-TYMSOS) play important roles in the development and treatment of NSCLC.

FRONTIERS IN MOLECULAR BIOSCIENCES (2022)

Article Biochemical Research Methods

CeRNASeek: an R package for identification and analysis of ceRNA regulation

Mengying Zhang et al.

Summary: CeRNASeek is an R package that integrates multiple-omics data to identify and analyze ceRNA-ceRNA interactions. It provides six computational methods and various downstream analyses, suitable for studying the function of ceRNAs in complex diseases.

BRIEFINGS IN BIOINFORMATICS (2021)

Article Cell Biology

Restoration of miR-330 expression suppresses lung cancer cell viability, proliferation, and migration

Ali Mohammadi et al.

Summary: Low miR-330 expression in lung cancer predicts poor prognosis, but stable restoration of miR-330 expression can reduce cell viability, increase apoptotic cells, induce G2/M cell cycle arrest, and inhibit cell migration.

JOURNAL OF CELLULAR PHYSIOLOGY (2021)

Article Biotechnology & Applied Microbiology

A Nuclear Long Non-Coding RNA LINC00618 Accelerates Ferroptosis in a Manner Dependent upon Apoptosis

Zuli Wang et al.

Summary: Ferroptosis is primarily caused by intracellular iron activity and lipid peroxidation, while LINC00618 promotes apoptosis and ferroptosis by regulating the levels of BAX, caspase-3, ROS, and iron. LSH and SLC7A11 also play crucial roles in this process.

MOLECULAR THERAPY (2021)

Article Biochemistry & Molecular Biology

miR-195-5p exerts tumor-suppressive functions in human lung cancer cells through targeting TrxR2

Lina Bu et al.

Summary: The microRNA miR-195-5p acts as a tumor suppressor in lung adenocarcinoma (LUAD) cells by targeting TrxR2, leading to inhibition of cell proliferation, migration, and invasion, as well as induction of apoptosis. Knockdown of TrxR2 mimics the tumor-suppressive effects of miR-195-5p overexpression, while overexpression of TrxR2 reverses these effects in A549 and PC-9 cells. Additionally, miR-195-5p overexpression inhibits the growth of xenografted A549 tumors in nude mice, suggesting its potential as a biomarker for LUAD therapy.

ACTA BIOCHIMICA ET BIOPHYSICA SINICA (2021)

Article Oncology

Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

Hyuna Sung et al.

Summary: The global cancer burden in 2020 saw an estimated 19.3 million new cancer cases and almost 10.0 million cancer deaths. Female breast cancer surpassed lung cancer as the most commonly diagnosed cancer, while lung cancer remained the leading cause of cancer death. These trends are expected to rise in 2040, with transitioning countries experiencing a larger increase compared to transitioned countries due to demographic changes and risk factors associated with globalization and a growing economy. Efforts to improve cancer prevention measures and provision of cancer care in transitioning countries will be crucial for global cancer control.

CA-A CANCER JOURNAL FOR CLINICIANS (2021)

Article Biophysics

Faradaic electrochemical impedance spectroscopy for enhanced analyte detection in diagnostics

Madison E. Strong et al.

Summary: EIS is a versatile technique with applications in various fields, particularly in biosensing for its high sensitivity and specificity in detecting a wide range of target analytes. It offers a cost-effective and rapid detection system with minimal sample volumes, making it ideal for medical diagnostics.

BIOSENSORS & BIOELECTRONICS (2021)

Article Oncology

MicroRNAs: Emerging oncogenic and tumor-suppressive regulators, biomarkers and therapeutic targets in lung cancer

Shengjie Tang et al.

Summary: MicroRNAs play pivotal roles in lung cancer development and progression, serving as potential biomarkers and therapeutic targets. Research has revealed the importance of microRNAs in regulating lung cancer cell growth, spread, and metastasis.

CANCER LETTERS (2021)

Article Cell Biology

TYMSOS drives the proliferation, migration, and invasion of gastric cancer cells by regulating ZNF703 via sponging miR-4739

Yulan Gu et al.

Summary: This study identified a novel lncRNA TYMSOS plays a critical role in gastric cancer (GC) by promoting tumor growth through regulating proliferation, migration, invasion, and apoptosis of GC cells. TYMSOS may serve as a potential target for GC therapy.

CELL BIOLOGY INTERNATIONAL (2021)

Article Biochemistry & Molecular Biology

Inhibition of miR-144-3p exacerbates non-small cell lung cancer progression by targeting CEP55

Ming Li et al.

Summary: miR-144-3p inhibits CEP55 expression in non-small cell lung cancer cells, leading to suppression of cell proliferation and migration, and promotion of apoptosis.

ACTA BIOCHIMICA ET BIOPHYSICA SINICA (2021)

Review Biochemistry & Molecular Biology

Liquid biopsy for therapy monitoring in early-stage non-small cell lung cancer

Misako Nagasaka et al.

Summary: Liquid biopsy has become a valuable diagnostic tool for advanced NSCLC, with ctDNA analysis being a key method for identifying targetable mutations. Monitoring ctDNA in plasma can help assess treatment response and residual disease burden, and new methods like miRNA and lncRNA are also being explored for their potential in NSCLC diagnosis and monitoring.

MOLECULAR CANCER (2021)

Article Biochemistry & Molecular Biology

MyoData: An expression knowledgebase at single cell/nucleus level for the discovery of coding-noncoding RNA functional interactions in skeletal muscle

Davide Corso et al.

Summary: Non-coding RNAs, particularly long non-coding RNAs (lncRNAs) and microRNAs (miRNAs), play crucial roles in regulating gene expression in skeletal muscle. The study focuses on constructing interaction networks based on expression correlations of coding and non-coding genes within single myofibers. Integration of KEGG pathways with miRNAs and lncRNAs provides insights into the specific functions of genes in different physiological conditions.

COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL (2021)

Review Biochemistry & Molecular Biology

LncRNA H19: A novel oncogene in multiple cancers

Jun Yang et al.

Summary: Long non-coding RNAs (lncRNAs) play important roles in cancers, among which H19 has attracted attention due to its abnormal expression in malignant tumors and involvement in malignant progression in various cancers.

INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES (2021)

Review Oncology

RNA in cancer

Gregory J. Goodall et al.

Summary: Recent findings have shown that RNA processing is systematically altered in cancer, with mutations in RNA splicing factor genes and the shortening of 3' untranslated regions widely observed. Additionally, evidence suggests that other types of RNAs, including circular RNAs, can contribute to tumorigenesis.

NATURE REVIEWS CANCER (2021)

Article Biochemistry & Molecular Biology

miRDB: an online database for prediction of functional microRNA targets

Yuhao Chen et al.

NUCLEIC ACIDS RESEARCH (2020)

Article Biochemistry & Molecular Biology

DIANA-LncBase v3: indexing experimentally supported miRNA targets on non-coding transcripts

Dimitra Karagkouni et al.

NUCLEIC ACIDS RESEARCH (2020)

Article Biochemistry & Molecular Biology

Distinct Processing of lncRNAs Contributes to Non-conserved Functions in Stem Cells

Chun-Jie Guo et al.

Article Biochemistry & Molecular Biology

Construction of lncRNA-associated ceRNA networks to identify prognostic lncRNA biomarkers for glioblastoma

Zhendong Liu et al.

JOURNAL OF CELLULAR BIOCHEMISTRY (2020)

Article Medicine, Research & Experimental

A Long Intergenic Non-coding RNA, LINC01426, Promotes Cancer Progression via AZGP1 and Predicts Poor Prognosis in Patients with LUAD

Baorui Tian et al.

MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT (2020)

Article Biochemistry & Molecular Biology

LncRNA SNHG12 promotes tumorigenesis and metastasis in osteosarcoma by upregulating Notch2 by sponging miR-195-5p

Sheng Zhou et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2018)

Article Multidisciplinary Sciences

miRWalk: An online resource for prediction of microRNA binding sites

Carsten Sticht et al.

PLOS ONE (2018)

Review Multidisciplinary Sciences

The biology and management of non-small cell lung cancer

Roy S. Herbst et al.

NATURE (2018)

Article Oncology

Synthetic Lethality Interaction Between Aurora Kinases and CHEK1 Inhibitors in Ovarian Cancer

Ana Alcaraz-Sanabria et al.

MOLECULAR CANCER THERAPEUTICS (2017)

Article Biochemistry & Molecular Biology

GEPIA: a web server for cancer and normal gene expression profiling and interactive analyses

Zefang Tang et al.

NUCLEIC ACIDS RESEARCH (2017)

Review Biochemistry & Molecular Biology

LncRNA-mediated regulation of cell signaling in cancer

W-X Peng et al.

ONCOGENE (2017)

Review Biochemistry & Molecular Biology

Beyond cytokinesis: the emerging roles of CEP55 in tumorigenesis

J. Jeffery et al.

ONCOGENE (2016)

Article Medicine, Research & Experimental

Long Intergenic Noncoding RNA 00511 Acts as an Oncogene in Non-small-cell Lung Cancer by Binding to EZH2 and Suppressing p57

Cheng-Cao Sun et al.

MOLECULAR THERAPY-NUCLEIC ACIDS (2016)

Review Biochemistry & Molecular Biology

Tools for Sequence-Based miRNA Target Prediction: What to Choose?

Angela L. Riffo-Campos et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2016)

Article

Correlation between EGFR Gene Mutations and Lung Cancer: a Hospital-Based Study

Matam Kavitha et al.

Asian Pacific Journal of Cancer Prevention (2015)

Article Mathematical & Computational Biology

cytoHubba: identifying hub objects and sub-networks from complex interactome

Chia-Hao Chin et al.

BMC SYSTEMS BIOLOGY (2014)

Review Oncology

Functions of lncRNA HOTAIR in lung cancer

Gregory Loewen et al.

JOURNAL OF HEMATOLOGY & ONCOLOGY (2014)

Article Biochemistry & Molecular Biology

starBase v2.0: decoding miRNA-ceRNA, miRNA-ncRNA and protein-RNA interaction networks from large-scale CLIP-Seq data

Jun-Hao Li et al.

NUCLEIC ACIDS RESEARCH (2014)

Article Biochemistry & Molecular Biology

CPAT: Coding-Potential Assessment Tool using an alignment-free logistic regression model

Liguo Wang et al.

NUCLEIC ACIDS RESEARCH (2013)

Review Cell Biology

Knowing when to but and run: mechanisms that control cytokinetic abscission

Monica Agromayor et al.

TRENDS IN CELL BIOLOGY (2013)

Article Biochemical Research Methods

PhyloCSF: a comparative genomics method to distinguish protein coding and non-coding regions

Michael F. Lin et al.

BIOINFORMATICS (2011)

Article Biochemistry & Molecular Biology

A ceRNA Hypothesis: The Rosetta Stone of a Hidden RNA Language?

Leonardo Salmena et al.

Article Biochemistry & Molecular Biology

Cytoscape: A software environment for integrated models of biomolecular interaction networks

P Shannon et al.

GENOME RESEARCH (2003)

Article Biochemistry & Molecular Biology

STRING: a database of predicted functional associations between proteins

C von Mering et al.

NUCLEIC ACIDS RESEARCH (2003)