☆ 4.6 Article

Programmed cell death: Past, present and future

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2022)

Related references

Note: Only part of the references are listed.

Article Biochemistry & Molecular Biology

Mouse oocytes develop in cysts with the help of nurse cells

Wanbao Niu et al.

Summary: Research findings show that mouse germline cysts periodically activate nurse cells for cytoplasmic transfer, which leads to shrinkage and turnover within 2 days. Nurse cells cluster with pro-oocyte sisters before initiation of transfer, but separate during the final 2 days. Genes promoting oocyte development and nurse cell programmed cell death (PCD) are upregulated, while genes repressing transfer are under-expressed.

CELL (2022)

Add to Collection

Article Biochemistry & Molecular Biology

Necroptosis as a Novel Facet of Mitotic Catastrophe

Aleksandra Yu Egorshina et al.

Summary: Mitotic catastrophe is a defensive mechanism that promotes elimination of cells with aberrant mitosis by triggering cell death pathways. In certain conditions, mitotic catastrophe can precede necroptosis in addition to apoptosis and autophagy.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)

Add to Collection

Article Cell Biology

Optogenetic activators of apoptosis, necroptosis, and pyroptosis

Kateryna Shkarina et al.

Summary: By utilizing optoCDEs, a novel class of optogenetic tools, targeted induction of different forms of programmed cell death can be achieved in a rapid and specific manner. These tools are suitable for a wide range of applications in vitro and in vivo. The assessment of neighboring cell responses to different types of cell death using optoCDEs has revealed a new regulatory role for shingosine-1-phosphate signaling in the engulfment of apoptotic cells by epithelial cells.

JOURNAL OF CELL BIOLOGY (2022)

Add to Collection

Article Multidisciplinary Sciences

A non-canonical vitamin K cycle is a potent ferroptosis suppressor

Eikan Mishima et al.

Summary: A study identifies the anti-ferroptotic function of vitamin K and reveals FSP1 as the enzyme mediating warfarin-resistant vitamin K reduction, highlighting the importance of FSP1 in protecting cells against lipid peroxidation and ferroptosis.

NATURE (2022)

Add to Collection

Review Biochemistry & Molecular Biology

Getting out what you put in: Copper in mitochondria and its impacts on human disease

Paul A. Cobine et al.

Summary: Mitochondria accumulate copper through MCF proteins for the maturation of copper enzymes, involving transporters like Pic2 and SLC25A3. Copper and copper proteins play essential roles in regulating cellular copper balance and inter-organ communication, while matrix copper may also have a role in novel cell death pathway cuproptosis.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2021)

Add to Collection

Review Cell Biology

Ferroptosis: mechanisms, biology and role in disease

Xuejun Jiang et al.

Summary: Ferroptosis, as a form of regulated cell death driven by iron-dependent phospholipid peroxidation, has seen significant growth in research in recent years. Studies have focused on molecular mechanisms, regulation, and functions of ferroptosis, linking this cell death modality to various pathologies and proposing its roles in normal physiology and potential therapeutic targeting.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2021)

Add to Collection

Article Cell Biology

ADAR1 restricts ZBP1-mediated immune response and PANoptosis to promote tumorigenesis

Rajendra Karki et al.

Summary: The study uncovers the role of ADAR1 in suppressing ZBP1-mediated PANoptosis and promoting tumorigenesis. Additionally, the use of IFN-gamma and NEI KPT-330 regresses melanoma in a ZBP1-dependent manner, providing important insights for cancer therapeutic strategies.

CELL REPORTS (2021)

Add to Collection

Article Cell Biology

TNF-induced necroptosis initiates early autophagy events via RIPK3-dependent AMPK activation, but inhibits late autophagy

Wenxian Wu et al.

Summary: This study identified RIPK3 as an AMPK-activating kinase, establishing a direct link between the kinases regulating autophagy and necroptosis.Activation of AMPK by RIPK3 leads to phosphorylation of autophagy-regulating proteins ULK1 and BECN1, while TNF-induced necroptosis blocks lysosomal degradation of autophagosomes. Dysregulation of SNARE complexes, including reduced levels of full-length STX17, was observed upon TNF treatment.

AUTOPHAGY (2021)

Add to Collection

Article Multidisciplinary Sciences

AIM2 forms a complex with pyrin and ZBP1 to drive PANoptosis and host defence

SangJoon Lee et al.

Summary: Inflammasomes are essential for innate immune defence, sensing pathogens and inducing cell death. They can detect multiple molecular patterns released by live pathogens during infection, activating multiple inflammasome sensors simultaneously. The study found that AIM2 regulates innate immune sensors pyrin and ZBP1 to drive inflammatory signalling and a form of inflammatory cell death known as PANoptosis, providing host protection during infections with specific pathogens.

NATURE (2021)

Add to Collection

Article Cell Biology

Lysosomal Machinery Drives Extracellular Acidification to Direct Non-apoptotic Cell Death

Albert A. Mondragon et al.

CELL REPORTS (2019)

Add to Collection

Article Multidisciplinary Sciences

Autophagy genes in myeloid cells counteract IFNγ-induced TNF-mediated cell death and fatal TNF-induced shock

Anthony Orvedahl et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)

Add to Collection

Article Multidisciplinary Sciences

Caspase-8 is the molecular switch for apoptosis, necroptosis and pyroptosis

Melanie Fritsch et al.

NATURE (2019)

Add to Collection

Article Multidisciplinary Sciences

Activity of caspase-8 determines plasticity between cell death pathways

Kim Newton et al.

NATURE (2019)

Add to Collection

Review Biochemistry & Molecular Biology

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

Lorenzo Galluzzi et al.

CELL DEATH AND DIFFERENTIATION (2018)

Add to Collection

Review Pharmacology & Pharmacy

Mitotic catastrophe and cancer drug resistance: A link that must to be broken

Tatiana V. Denisenko et al.

DRUG RESISTANCE UPDATES (2016)

Add to Collection

Article Cell Biology

The plasma membrane channel ORAI1 mediates detrimental calcium influx caused by endogenous oxidative stress

N. Henke et al.

CELL DEATH & DISEASE (2013)

Add to Collection

Article Biochemistry & Molecular Biology

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

Scott J. Dixon et al.

CELL (2012)

Add to Collection

Review Biochemistry & Molecular Biology

Eaten alive! Cell death by primary phagocytosis: 'phagoptosis'

Guy C. Brown et al.

TRENDS IN BIOCHEMICAL SCIENCES (2012)

Add to Collection

Article Multidisciplinary Sciences

Catalytic activity of the caspase-8-FLIPL complex inhibits RIPK3-dependent necrosis

Andrew Oberst et al.

NATURE (2011)

Add to Collection

Review Biochemistry & Molecular Biology

Worms, life and death

HR Horvitz

BIOSCIENCE REPORTS (2003)

Add to Collection

Article Biochemistry & Molecular Biology

Cleavage of plasma membrane calcium pumps by caspases: a link between apoptosis and necrosis

BL Schwab et al.

CELL DEATH AND DIFFERENTIATION (2002)

Add to Collection

Review Multidisciplinary Sciences

Calcium signaling: A tale for all seasons

E Carafoli

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)

Add to Collection

© Peeref 2019-2024. All rights reserved.