Journal
APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY
Volume 195, Issue 4, Pages 2451-2462Publisher
SPRINGER
DOI: 10.1007/s12010-022-04300-0
Keywords
Nipah virus (NiV); Zoonotic; Encephalitis; Epidemiology; Pathology; Septicemia; Seroprevalence
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Nipah virus is a zoonotic disease transmitted by bats, causing severe respiratory illness and encephalitis. Multiple outbreaks have occurred in Malaysia and other countries, emphasizing the urgent need for clinical trials to establish prevention and treatment methods.
Viral diseases are causing mayhem throughout the world. One of the zoonotic viruses that have emerged as a potent threat to community health in the past few decades is Nipah virus. Nipah viral sickness is a zoonotic disease whose main carrier is bat. This disease is caused by Nipah virus (NiV). It belongs to the henipavirous group and of the family paramyxoviridae. Predominantly Pteropus spp. is the carrier of this virus. It was first reported from the Kampung Sungai Nipah town of Malaysia in 1998. Human-to-human transmission can also occur. Several repeated outbreaks were reported from South and Southeast Asia in the recent past. In humans, the disease is responsible for rapid development of acute illness, which can result in severe respiratory illness and serious encephalitis. Therefore, this calls for an urgent need for health authorities to conduct clinical trials to establish possible treatment regimens to prevent any further outbreaks.
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