☆ 4.8 Article

Quantitative Single-Molecule Electrochemiluminescence Bioassay

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2023)

Related references

Note: Only part of the references are listed.

Article Chemistry, Analytical

Single-Electrode Electrochemical System for the Visual and High-Throughput Electrochemiluminescence Immunoassay

Fangxin Du et al.

Summary: A novel single-electrode electrochemical system (SEES) was developed for visual and high-throughput ECL immunoassay. The SEES combines a plastic sticker and carbon ink screen-printed electrode, offering simplicity, cost-effectiveness, and user-friendliness. Using a smartphone as the detector, the SEES enables the determination of the concentration range of a specific biomarker, cTnI, with a low detection limit. Compared to conventional electrode systems, the SEES shows superior advantages and holds great potential in point-of-care testing.

ANALYTICAL CHEMISTRY (2022)

Add to Collection

Article Chemistry, Multidisciplinary

Operando Imaging of Chemical Activity on Gold Plates with Single-Molecule Electrochemiluminescence Microscopy

Jinrun Dong et al.

Summary: Here, we demonstrate super-resolution imaging of Ru(bpy)(3)(2+) reactions on Au plates using single-molecule electrochemiluminescence microscopy, achieving high spatial resolution and sensitivity to single photons. The spatiotemporally resolved dynamic structure-activity relationship on Au plates reveals the importance of catalyst restructuring in determining reactivity.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2022)

Add to Collection

Article Biochemical Research Methods

Correction of multiple-blinking artifacts in photoactivated localization microscopy

Louis G. Jensen et al.

Summary: This study presents a model-based correction workflow for correcting multiple-blinking artifacts in PALM data, resulting in improved localization precision. The corrected data can be tested for spatial randomness or analyzed using other clustering approaches. The effectiveness of this method is validated through simulations and experiments.

NATURE METHODS (2022)

Add to Collection

Article Chemistry, Multidisciplinary

Boron-Doped Diamond Electrode Outperforms the State-of-the-ArtElectrochemiluminescence from Microbeads Immunoassay

Kohei Sakanoue et al.

Summary: Electrochemiluminescence (ECL) is a powerful technique for clinical analysis. This research focuses on microbead-based ECL immunoassay using boron-doped diamond (BDD) as an electrode material, and the results suggest that BDD can enhance the sensitivity of ECL.

ACS SENSORS (2022)

Add to Collection

Review Chemistry, Physical

Electrochemistry probed one molecule at a time

Jiandong Feng

Summary: Probing electrochemical reactions at the single-reaction level is the ultimate goal for electroanalytical chemistry. The development of electrical approaches and optical methods has enabled studying the electrochemistry of individual molecules in various systems, providing new insights for fundamental electrochemistry, electroanalytical applications, and electrochemical cells. Further improving spatial and temporal resolution and developing new techniques are potential directions for future advancements.

CURRENT OPINION IN ELECTROCHEMISTRY (2022)

Add to Collection

Article Chemistry, Multidisciplinary

Single Biomolecule Imaging by Electrochemiluminescence

Yujie Liu et al.

Summary: This study successfully imaged single biomolecules using RuDSNs/AuNPs as ECL nanoemitters, demonstrating the visualization of single protein molecules and single membrane proteins in cells, overcoming the challenges in ultrasensitive ECL analysis and providing valuable information for cellular biology research.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2021)

Add to Collection

Review Chemistry, Physical

Recent advances in electrochemiluminescence immunoassay based on multiple-signal strategy

Fangxin Du et al.

Summary: This review summarizes recent advances in ECL strategies with multiple-signal outputs, including ratiometric ECL, ECL multiplex immunoassay (MIA), and ECL imaging, discussing their signal generation strategies and applications in immunoassays. Challenges and prospects in this field are also addressed.

CURRENT OPINION IN ELECTROCHEMISTRY (2021)

Add to Collection

Article Multidisciplinary Sciences

Direct imaging of single-molecule electrochemical reactions in solution

Jinrun Dong et al.

Summary: Optical imaging of single-molecule electrochemical reactions in aqueous solution enables super-resolution electrochemiluminescence microscopy, providing high spatiotemporal resolution for monitoring adhesion dynamics of live cells. Single-molecule methods go beyond ensemble averages and reveal statistical distribution of reaction positions, pathways, and dynamics, advancing fundamental understanding of electrochemical reactions and proving useful for bioassays and cell-imaging applications.

NATURE (2021)

Add to Collection

Review Chemistry, Multidisciplinary

Advances in Optical Single-Molecule Detection: En Route to Supersensitive Bioaffinity Assays

Zdenek Farka et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2020)

Add to Collection

Article Multidisciplinary Sciences

Insights into the mechanism of coreactant electrochemiluminescence facilitating enhanced bioanalytical performance

Alessandra Zanut et al.

NATURE COMMUNICATIONS (2020)

Add to Collection

Article Chemistry, Multidisciplinary

Single Molecule Protein Detection with Attomolar Sensitivity Using Droplet Digital Enzyme-Linked Immunosorbent Assay

Limor Cohen et al.

ACS NANO (2020)

Add to Collection

Article Chemistry, Multidisciplinary

Dye-Doped Silica Nanoparticles for Enhanced ECL-Based Immunoassay Analytical Performance

Alessandra Zanut et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2020)

Add to Collection

Article Chemistry, Analytical

Potential-Resolved Electrochemiluminescence Nanoprobes for Visual Apoptosis Evaluation at Single-Cell Level

Gen Liu et al.

ANALYTICAL CHEMISTRY (2019)

Add to Collection

Article Chemistry, Analytical

Electrochemiluminescence Imaging for Bioanalysis

Jingjing Zhang et al.

ANNUAL REVIEW OF ANALYTICAL CHEMISTRY, VOL 12 (2019)

Add to Collection

Article Chemistry, Multidisciplinary

Potential-Resolved Multicolor Electrochemiluminescence for Multiplex Immunoassay in a Single Sample

Weiliang Guo et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2018)

Add to Collection

Article Chemistry, Multidisciplinary

Surface-Confined Electrochemiluminescence Microscopy of Cell Membranes

Silvia Voci et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2018)

Add to Collection

Review Chemistry, Multidisciplinary

Fluorescent Biosensors Based on Single-Molecule Counting

Fei Ma et al.

ACCOUNTS OF CHEMICAL RESEARCH (2016)

Add to Collection

Article Multidisciplinary Sciences

Complementarity of PALM and SOFI for super-resolution live-cell imaging of focal adhesions

Hendrik Deschout et al.

NATURE COMMUNICATIONS (2016)

Add to Collection

Review Chemistry, Multidisciplinary

Cancer biomarker detection: recent achievements and challenges

Li Wu et al.

CHEMICAL SOCIETY REVIEWS (2015)

Add to Collection

Article Biochemical Research Methods

Synthesis, labeling and bioanalytical applications of a tris(2,2′-bipyridyl) ruthenium(II)-based electrochemiluminescence probe

Xiaoming Zhou et al.

NATURE PROTOCOLS (2014)

Add to Collection

Letter Biochemical Research Methods

Identification of clustering artifacts in photoactivated localization microscopy

Paolo Annibale et al.

NATURE METHODS (2011)

Add to Collection

Article Biotechnology & Applied Microbiology

Single-molecule enzyme-linked immunosorbent assay detects serum proteins at subfemtomolar concentrations

David M. Rissin et al.

NATURE BIOTECHNOLOGY (2010)

Add to Collection

Article Chemistry, Multidisciplinary

Multiplexed Sandwich Immunoassays Using Electrochemiluminescence Imaging Resolved at the Single Bead Level

Frederique Deiss et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2009)

Add to Collection

Review Multidisciplinary Sciences

Mining the plasma proteome for cancer biomarkers

Samir M. Hanash et al.

NATURE (2008)

Add to Collection

Article Chemistry, Analytical

Electrogenerated chemiluminescence sensors using Ru(bpy)32+ doped in silica nanoparticles

Lihua Zhang et al.

ANALYTICAL CHEMISTRY (2006)

Add to Collection

Article Chemistry, Multidisciplinary

Electrogenerated chemiluminescence 69:: The tris(2,2′-bipyridine)ruthenium(II), (Ru(bpy)32+)/tri-n-propylamine (TPrA) system revisited -: A new route involving TPrA•+ cation radicals

WJ Miao et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2002)

Add to Collection

Article Chemistry, Analytical

Electrogenerated chemiluminescence.: 67.: Dependence of light emission of the tris(2,2′)bipyridylruthenium(II)/tripropylamine system on electrode surface hydrophobicity

YB Zu et al.

ANALYTICAL CHEMISTRY (2001)

Add to Collection

© Peeref 2019-2024. All rights reserved.