☆ 4.8 Article

Dry Chemistry-Based Bipolar Electrochemiluminescence Immunoassay Device for Point-of-Care Testing of Alzheimer-Associated Neuronal Thread Protein

ANALYTICAL CHEMISTRY (2023)

Related references

Note: Only part of the references are listed.

Article Chemistry, Analytical

Paper-Based Bipolar Electrode Electrochemiluminescence Platform Combined with Pencil-Drawing Trace for the Detection of M.SssI Methyltransferase

Lin Zhu et al.

Summary: In this study, a hand-drawing paper-based bipolar electrode electrochemiluminescence platform was developed for the detection of M.SssI methyltransferase. The platform utilized high electrocatalytic Pt@CeO2 as an ECL co-reaction accelerator and pencil-drawing graphite electric circuits as wires and electrodes. The platform provides a convenient, low-cost and easy-to-operate solution for early disease diagnosis and pathogenesis research.

ANALYTICAL CHEMISTRY (2022)

Add to Collection

Article Chemistry, Analytical

Electrochemiluminescence sensor for point-of-care detection of pyrrolizidine alkaloids

Yi Xiao et al.

Summary: In this study, a visual, easy-to-use, and economic sensor was developed for confirmative measurement of PAs in routine clinical tests. The sensor exhibited excellent linearity, low detection limits, and good recoveries, indicating good accuracy and practicability. This portable and low-cost sensor holds promise to be applied to point-of-care testing of PAs in drugs, food products, and clinical samples.

TALANTA (2022)

Add to Collection

Review Neurosciences

Biofluid Biomarkers of Alzheimer's Disease: Progress, Problems, and Perspectives

Shan Huang et al.

Summary: The diagnosis of Alzheimer's disease (AD) has become more precise with the introduction of the biomarker-based A-T-N (Amyloid/Tau/Neurodegeneration) framework. However, this framework does not cover the entire spectrum of AD pathologies and the invasive nature and high costs of the diagnostic methods for the central nervous system pose limitations. Therefore, adding an X to the A-T-N framework and focusing on peripheral biomarkers in the diagnosis of AD is recommended.

NEUROSCIENCE BULLETIN (2022)

Add to Collection

Article Chemistry, Analytical

A fully integrated and handheld electrochemiluminescence device for detection of dopamine in bio-samples

Lihang Zhu et al.

Summary: This study presents a fully integrated and handheld ECL device, consisting of a flexible printed circuit board based electrochemical module, a silicon photomultiplier, and a Bluetooth enabled smartphone. The device has a compact size, making it suitable for on-site detection and POCT. Experimental results demonstrate that the device exhibits fast response to dopamine and meets the basic requirements for POCT in complex bio-samples.

SENSORS AND ACTUATORS B-CHEMICAL (2022)

Add to Collection

Article Chemistry, Analytical

Ultrasensitive Electrochemiluminescence Biosensor Based on Closed Bipolar Electrode for Alkaline Phosphatase Detection in Single Liver Cancer Cell

Xiao-Yan Yang et al.

Summary: An ultrasensitive electrochemiluminescence biosensor based on a closed bipolar electrode was proposed for the detection of alkaline phosphatase. The sensitivity of the system was greatly enhanced by utilizing enzyme catalysis for signal amplification and electrodeposition of Au nanoparticles on the cathode surface. This biosensor showed high sensitivity and specificity, with a detection limit as low as 3.7 aM, and successfully realized ALP detection in single cells.

ANALYTICAL CHEMISTRY (2021)

Add to Collection

Review Neurosciences

Alzheimer-Associated Neuronal Thread Protein: Research Course and Prospects for the Future

He Jin et al.

Summary: Alzheimer's disease is the leading cause of dementia, and the prevalence is increasing globally. AD7c-NTP has been identified as a potential biomarker for diagnosing AD and MCI, particularly in urine tests which are non-invasive and more easily accepted by patients. The use of AD7c-NTP as a biomarker has undergone extensive research over nearly 25 years, but its detection in urine has sparked controversy compared to traditional sources like CSF or blood.

JOURNAL OF ALZHEIMERS DISEASE (2021)

Add to Collection

Article Chemistry, Analytical

Electrochemiluminescence-Incorporated Lateral Flow Immunosensors Using Ru(bpy)32+-Labeled Gold Nanoparticles for the Full-Range Detection of Physiological C-Reactive Protein Levels

Donggu Hong et al.

Summary: CRP is a general biomarker for inflammation and infection, and the ECL-LFI is an electrochemiluminescent lateral flow immunosensor that allows full-range CRP detection with high sensitivity and a broad detection range, showing great potential for CRP detection in point-of-care diagnostics.

ANALYTICAL CHEMISTRY (2021)

Add to Collection

Article Geriatrics & Gerontology

Comparison of Urinary Alzheimer-Associated Neural Thread Protein (AD7c-NTP) Levels Between Patients With Amnestic and Nonamnestic Mild Cognitive Impairment

Bon D. Ku et al.

AMERICAN JOURNAL OF ALZHEIMERS DISEASE AND OTHER DEMENTIAS (2020)

Add to Collection

Article Biophysics

Precision medicine in Alzheimer's disease: An origami paper-based electrochemical device for cholinesterase inhibitors

Veronica Caratelli et al.

BIOSENSORS & BIOELECTRONICS (2020)

Add to Collection

Article Chemistry, Multidisciplinary

Ru(bpy)32+-Loaded Mesoporous Silica Nanoparticles as Electrochemiluminescent Probes of a Lateral Flow Immunosensor for Highly Sensitive and Quantitative Detection of Troponin I

Donggu Hong et al.

SMALL (2020)

Add to Collection

Article Chemistry, Analytical

Switches-controlled bipolar electrode electrochemiluminescence arrays for high-throughput detection of cancer biomarkers

Shou-Nian Ding et al.

JOURNAL OF ELECTROANALYTICAL CHEMISTRY (2019)

Add to Collection

Review Biochemistry & Molecular Biology

When Does Alzheimer′s Disease Really Start? The Role of Biomarkers

Ana Lloret et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)

Add to Collection

Article Neurosciences

Some Methodological Characteristics of Alzheimer-Associated Urine Neuronal Thread Protein Detected by Enzyme-Linked Immunosorbent Assay

He Jin et al.

JOURNAL OF ALZHEIMERS DISEASE (2018)

Add to Collection

Article Chemistry, Analytical

A signal-on switch electrochemiluminescence biosensor for the detection of tumor cells

Qian Kun et al.

JOURNAL OF ELECTROANALYTICAL CHEMISTRY (2018)

Add to Collection

Article Neurosciences

Urine AD7c-NTP Predicts Amyloid Deposition and Symptom of Agitation in Patients with Alzheimer's Disease and Mild Cognitive Impairment

Nan Zhang et al.

JOURNAL OF ALZHEIMERS DISEASE (2017)

Add to Collection

Article Chemistry, Multidisciplinary

Fluorescent microsphere immunochromatographic assays for detecting bone alkaline phosphatase based on biolayer interferometry-selected antibody

Miao Liu et al.

RSC ADVANCES (2017)

Add to Collection

Article Medical Laboratory Technology

Development of a Novel Urine Alzheimer-Associated Neuronal Thread Protein ELISA Kit and Its Potential Use in the Diagnosis of Alzheimer's Disease

Lina Ma et al.

JOURNAL OF CLINICAL LABORATORY ANALYSIS (2016)

Add to Collection

Review Clinical Neurology

A/T/N: An unbiased descriptive classification scheme for Alzheimer disease biomarkers

Clifford R. Jack et al.

NEUROLOGY (2016)

Add to Collection

Article Biotechnology & Applied Microbiology

Combining serum and urine biomarkers in the early diagnosis of mild cognitive impairment that evolves into Alzheimer's disease in patients with the apolipoprotein E ε4 genotype

Chao Wang et al.

BIOMARKERS (2015)

Add to Collection

Article Chemistry, Analytical

Ultrasensitive electrochemiluminescent detection of cardiac troponin I based on a self-enhanced Ru(II) complex

Ying Zhou et al.

TALANTA (2014)

Add to Collection

Article Chemistry, Analytical

Use of a mobile phone for potentiostatic control with low cost paper-based microfluidic sensors

Jacqui L. Delaney et al.

ANALYTICA CHIMICA ACTA (2013)

Add to Collection

Review Clinical Neurology

A literature review of AD7c-ntp as a biomarker for Alzheimer's disease

Jian Zhang et al.

ANNALS OF INDIAN ACADEMY OF NEUROLOGY (2013)

Add to Collection

Review Clinical Neurology

Research criteria for the diagnosis of Alzheimers disease: revising the NINCDS-ADRDA criteria

Bruno Dubois et al.

LANCET NEUROLOGY (2007)

Add to Collection

© Peeref 2019-2024. All rights reserved.