Case Report: Symptomatic Herpes Simplex Virus Type 2 and Monkeypox Coinfection in an Adult Male

A 39-year-old man presented with a history of fatigue, malaise, and rash with varied morphology on his perianal region. Polymerase chain reaction testing of the lesions confirmed coinfection with monkeypox and herpes sim-plex virus type 2. We emphasize the difficulty in distinguishing between monkeypox virus and herpes simplex virus type 2 based on history and examination alone.

Automated summary

A 39-year-old male presented with fatigue, malaise, and rash on his perianal region. PCR testing confirmed coinfection with monkeypox and herpes simplex virus type 2. It is difficult to distinguish between the two viruses based solely on history and examination.