4.7 Article

PARP inhibition in leukocytes diminishes inflammation via effects on integrins/cytoskeleton and protects the blood-brain barrier

Related references

Note: Only part of the references are listed.
Review Clinical Neurology

The Role of Neuroinflammation in Dementias

Giuseppe Pasqualetti et al.

CURRENT NEUROLOGY AND NEUROSCIENCE REPORTS (2015)

Editorial Material Pharmacology & Pharmacy

Poly(ADP-ribose) polymerase inhibitor therapeutic effect: are we just scratching the surface?

Michael O. Hottiger

EXPERT OPINION ON THERAPEUTIC TARGETS (2015)

Article Endocrinology & Metabolism

miR-98 and let-7g*protect the blood-brain barrier under neuroinflammatory conditions

Slava Rom et al.

JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2015)

Review Cell Biology

PARP-1 involvement in neurodegeneration: A focus on Alzheimer's and Parkinson's diseases

Sara Martire et al.

MECHANISMS OF AGEING AND DEVELOPMENT (2015)

Article Biochemistry & Molecular Biology

The role of poly(ADP-ribose) polymerase-1 inhibitor in carrageenan-induced lung inflammation in mice

Sheikh Fayaz Ahmad et al.

MOLECULAR IMMUNOLOGY (2015)

Review Clinical Neurology

Immune interventions in stroke

Ying Fu et al.

NATURE REVIEWS NEUROLOGY (2015)

Review Cell Biology

Inflammation, Iron, Energy Failure, and Oxidative Stress in the Pathogenesis of Multiple Sclerosis

Lukas Haider

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2015)

Review Endocrinology & Metabolism

Poly(ADP-ribose) polymerases as modulators of mitochondrial activity

Peter Bai et al.

TRENDS IN ENDOCRINOLOGY AND METABOLISM (2015)

Meeting Abstract Biochemistry & Molecular Biology

p38α deficiency and oxidative stress cause cytokinesis failure in hepatocytes

M. Tormos Ana et al.

FREE RADICAL BIOLOGY AND MEDICINE (2014)

Article Gastroenterology & Hepatology

Poly (ADP-Ribose) Polymerase-1 Is a Key Mediator of Liver Inflammation and Fibrosis

Partha Mukhopadhyay et al.

HEPATOLOGY (2014)

Review Endocrinology & Metabolism

Neurogenesis and inflammation after ischemic stroke: what is known and where we go from here

Matthew K. Tobin et al.

JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2014)

Article Biochemical Research Methods

Removable cranial windows for long-term imaging in awake mice

Glenn J. Goldey et al.

NATURE PROTOCOLS (2014)

Article Biochemical Research Methods

Insights into the binding of PARP inhibitors to the catalytic domain of human tankyrase-2

Wei Qiu et al.

ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2014)

Article Behavioral Sciences

PARP1 enhances inflammatory cytokine expression by alteration of promoter chromatin structure in microglia

Ricardo Ivan Martinez-Zamudio et al.

BRAIN AND BEHAVIOR (2014)

Article Biochemical Research Methods

Structural basis for the inhibition of poly(ADP-ribose) polymerases 1 and 2 by BMN 673, a potent inhibitor derived from dihydropyridophthalazinone

Mika Aoyagi-Scharber et al.

ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS (2014)

Article Biotechnology & Applied Microbiology

Family-wide chemical profiling and structural analysis of PARP and tankyrase inhibitors

Elisabet Wahlberg et al.

NATURE BIOTECHNOLOGY (2012)

Review Immunology

Aspects of VLA-4 and LFA-1 regulation that may contribute to rolling and firm achesion

Alexandre Chigaev et al.

FRONTIERS IN IMMUNOLOGY (2012)

Review Neurosciences

Tight junctions at the blood brain barrier: physiological architecture and disease-associated dysregulation

Anny-Claude Luissint et al.

FLUIDS AND BARRIERS OF THE CNS (2012)

Review Pathology

Signaling Mechanism of Poly(ADP-Ribose) Polymerase-1 (PARP-1) in Inflammatory Diseases

Xueqing Ba et al.

AMERICAN JOURNAL OF PATHOLOGY (2011)

Review Biochemistry & Molecular Biology

How do immune cells overcome the blood-brain barrier in multiple sclerosis?

Catherine Larochelle et al.

FEBS LETTERS (2011)

Review Immunology

The insider's guide to leukocyte integrin signalling and function

Nancy Hogg et al.

NATURE REVIEWS IMMUNOLOGY (2011)

Review Cell Biology

Inflammatory mechanisms in ischemic stroke: role of inflammatory cells

Rong Jin et al.

JOURNAL OF LEUKOCYTE BIOLOGY (2010)

Review Oncology

PARP inhibition: PARP1 and beyond

Michele Rouleau et al.

NATURE REVIEWS CANCER (2010)

Article Biochemistry & Molecular Biology

Real-time Analysis of Conformation-sensitive Antibody Binding Provides New Insights into Integrin Conformational Regulation

Alexandre Chigaev et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2009)

Article Clinical Neurology

Temporal and Spatial Dynamics of Cerebral Immune Cell Accumulation in Stroke

Mathias Gelderblom et al.

STROKE (2009)

Article Hematology

PARP-1 inhibition prevents oxidative and nitrosative stress-induced endothelial cell death via transactivation of the VEGF receptor 2

Marlene T. Mathews et al.

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2008)

Review Pharmacology & Pharmacy

Poly(ADP-ribose)polymerase 1 (PARP-1) and postischemic brain damage

Flavio Moroni

CURRENT OPINION IN PHARMACOLOGY (2008)

Review Cell Biology

Roles of integrin activation in eosinophil function and the eosinophilic inflammation of asthma

Steven R. Barthel et al.

JOURNAL OF LEUKOCYTE BIOLOGY (2008)

Article Endocrinology & Metabolism

Contribution of poly(ADP-ribose) polymerase to postischemic blood-brain barrier damage in rats

Gabor Lenzser et al.

JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2007)

Review Physiology

Nitric oxide and peroxynitrite in health and disease

Pal Pacher et al.

PHYSIOLOGICAL REVIEWS (2007)

Article Neurosciences

Blood-brain Barrier: Structural Components and Function Under Physiologic and Pathologic Conditions

Yuri Persidsky et al.

JOURNAL OF NEUROIMMUNE PHARMACOLOGY (2006)

Review Cardiac & Cardiovascular Systems

Rho GTPases and leukocyte adhesion receptor expression and function in endothelial cells

E Cernuda-Morollón et al.

CIRCULATION RESEARCH (2006)

Review Cardiac & Cardiovascular Systems

Rho and vascular disease

BE Rolfe et al.

ATHEROSCLEROSIS (2005)

Article Neurosciences

Poly(ADP-Ribose) polymerase-1 activation in a primate model of multiple sclerosis

TM Kauppinen et al.

JOURNAL OF NEUROSCIENCE RESEARCH (2005)

Review Biotechnology & Applied Microbiology

Poly(ADP-ribose) polymerase and the therapeutic effects of its inhibitors

P Jagtap et al.

NATURE REVIEWS DRUG DISCOVERY (2005)

Article Biochemistry & Molecular Biology

Signaling through the leukocyte integrin LFA-1 in T cells induces a transient activation of Rac-1 that is regulated by Vav and PI3K/Akt-1

L Sánchez-Martín et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2004)

Review Immunology

Role of the cytoskeleton during leukocyte responses

M Vicente-Manzanares et al.

NATURE REVIEWS IMMUNOLOGY (2004)

Article Cardiac & Cardiovascular Systems

Attenuation of neointima formation through the inhibition of DNA repair enzyme PARP-1 in balloon-injured rat carotid artery

CX Zhang et al.

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2004)

Review Hematology

Signaling in leukocyte transendothelial migration

JD van Buul et al.

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2004)

Review Cell Biology

Actin cytoskeletal dynamics in T lymphocyte activation and migration

Y Samstag et al.

JOURNAL OF LEUKOCYTE BIOLOGY (2003)

Review Pharmacology & Pharmacy

The therapeutic potential of poly(ADP-ribose) polymerase inhibitors

L Virág et al.

PHARMACOLOGICAL REVIEWS (2002)

Article Endocrinology & Metabolism

Meningitis-associated central nervous system complications are mediated by the activation of poly(ADP-ribose) polymerase

U Koedel et al.

JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2002)

Article Clinical Neurology

Migration of multiple sclerosis lymphocytes through brain endothelium

A Prat et al.

ARCHIVES OF NEUROLOGY (2002)

Article Critical Care Medicine

Contribution of small GTPase Rho and its target protein ROCK in a murine model of lung fibrosis

Y Shimizu et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2001)