Immunosenescence and inflamm-ageing in COVID-19

The destructive effects of coronavirus disease 2019 (COVID-19) on the elderly and people with cardiovascular disease have been proven. New findings shed light on the role of aging pathways on life span and health age. New therapies that focus on aging-related pathways may positively impact the treatment of this acute respiratory infection. Using new therapies that boost the level of the immune system can support the elderly with comorbidities against the acute form of COVID-19. This article discusses the effect of the aging immune system against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the pathways affecting this severity of infection.

Automated summary

New findings suggest that targeting aging pathways can improve the treatment of COVID-19. Boosting the immune system with new therapies can help elderly individuals with comorbidities fight against severe forms of the virus.