4.8 Article

Activated Platelet-Targeted IR780 Immunoliposomes for Photothermal Thrombolysis

Related references

Note: Only part of the references are listed.
Article Chemistry, Multidisciplinary

Elaborately Engineering a Self-Indicating Dual-Drug Nanoassembly for Site-Specific Photothermal-Potentiated Thrombus Penetration and Thrombolysis

Zhiqiang Zhao et al.

Summary: This study proposes a method of using photothermal therapy to overcome the challenges of conventional thrombolytic treatments, achieving thrombus-targeted delivery through nanoscale assembly, and demonstrating high therapeutic efficacy.

ADVANCED SCIENCE (2022)

Article Materials Science, Multidisciplinary

Self-quenched liposomal probes for tumor imaging based on cellular on/off system

Yuqiong Xia et al.

Summary: Near-infrared fluorophores are widely used in tumor imaging due to their superior resolution, sensitivity, penetration depth, and low auto-fluorescence. However, the efficacy of these fluorophores in tumor imaging is often hindered by background signals and delivery efficiency. The self-quenched liposomal probes DiR-LP-C and DiR-LP-B have been developed as tumor-specific imaging probes with a cellular on/off system, showing potential for tumor imaging and phototherapy.

MATERIALS TODAY COMMUNICATIONS (2022)

Article Nanoscience & Nanotechnology

Silver/Iron Oxide Nano-Popcorns for Imaging and Therapy

Ateeque Ur Rehman et al.

Summary: Research introduced 120 nm silver/iron oxide hybrid nano-popcorns with tuned surface plasmon resonance in the near-infrared range for imaging and therapeutic applications, showing potential for photothermal treatment.

ACS APPLIED NANO MATERIALS (2021)

Article Chemistry, Multidisciplinary

Near-infrared light-responsive liposomes for protein delivery: Towards bleeding-free photothermally-assisted thrombolysis

Ahmed Refaat et al.

Summary: Smart drug delivery systems utilizing near-infrared light-responsive liposomal gold nanorods show potential for targeted therapy of cancer and cardiovascular diseases with minimal adverse effects. This novel platform combines light-triggered protein release with photothermal thrombolytic effects for site-specific thrombolysis, offering a promising approach for advanced medical treatment.

JOURNAL OF CONTROLLED RELEASE (2021)

Article Oncology

Liposomal IR-780 as a Highly Stable Nanotheranostic Agent for Improved Photothermal/Photodynamic Therapy of Brain Tumors by Convection-Enhanced Delivery

Yu-Jen Lu et al.

Summary: By entrapping IR-780 within the lipid bilayer of liposomes, enhanced photostability and cytotoxicity are achieved for improved effectiveness in PTT/PDT, inducing higher cell apoptosis rate.

CANCERS (2021)

Article Biochemistry & Molecular Biology

Rapid modification of antibodies on the surface of liposomes composed of high-affinity protein A-conjugated phospholipid for selective drug delivery

Susumu Hama et al.

Summary: The study demonstrates that liposomes displaying high-affinity Protein A (Protein A-R28) can undergo rapid modification with various antibodies, enabling selective drug delivery dependent on the target protein.

BIOCHEMISTRY AND BIOPHYSICS REPORTS (2021)

Article Biochemical Research Methods

An occlusive thrombosis-on-a-chip microfluidic device for investigating the effect of anti-thrombotic drugs

Jess Berry et al.

Summary: Cardiovascular disease is a leading cause of death worldwide, with myocardial infarction being triggered by blood clots. Developing new anti-platelet drugs is an active area of research, with in vitro models using human blood showing potential in improving relevance. The study developed a microfluidic device for generating occlusive thrombi and demonstrated its ability to monitor the effect of anti-thrombotic drugs in an unbiased and objective manner.

LAB ON A CHIP (2021)

Article Materials Science, Biomaterials

Hyperthermia-triggered UK release nanovectors for deep venous thrombosis therapy

Jiasheng Xu et al.

JOURNAL OF MATERIALS CHEMISTRY B (2020)

Article Hematology

Myocardial Infarction-From Atherosclerosis to Thrombosis Uncovering New Diagnostic and Therapeutic Approaches

Jathushan Palasubramaniam et al.

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2019)

Review Biochemical Research Methods

Platelet for drug delivery

Yifei Lu et al.

CURRENT OPINION IN BIOTECHNOLOGY (2019)

Article Chemistry, Multidisciplinary

Interventional Photothermal Therapy Enhanced Brachytherapy: A New Strategy to Fight Deep Pancreatic Cancer

Fengrong Zhang et al.

ADVANCED SCIENCE (2019)

Article Pharmacology & Pharmacy

Tissue plasminogen activator-based nanothrombolysis for ischemic stroke

Shan Liu et al.

EXPERT OPINION ON DRUG DELIVERY (2018)

Article Engineering, Biomedical

Cyclic RGD functionalized liposomes encapsulating urokinase for thrombolysis

Nengpan Zhang et al.

ACTA BIOMATERIALIA (2018)

Review Pharmacology & Pharmacy

IR780 based nanomaterials for cancer imaging and photothermal, photodynamic and combinatorial therapies

Catia G. Alves et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2018)

Article Cell Biology

Using flow cytometry to monitor glycoprotein IIb-IIIa activation

Andrew L. Frelinger

PLATELETS (2018)

Review Chemistry, Multidisciplinary

The principles and applications of avidin-based nanoparticles in drug delivery and diagnosis

Akshay Jain et al.

JOURNAL OF CONTROLLED RELEASE (2017)

Article Medicine, Research & Experimental

Near infrared fluorescent imaging of brain tumor with IR780 dye incorporated phospholipid nanoparticles

Shihong Li et al.

JOURNAL OF TRANSLATIONAL MEDICINE (2017)

Article Medicine, Research & Experimental

Comparison of Avidin, Neutravidin, and Streptavidin as Nanocarriers for Efficient siRNA Delivery

Akshay Jain et al.

MOLECULAR PHARMACEUTICS (2017)

Article Biotechnology & Applied Microbiology

Combined photothermal and photodynamic therapy by hyaluronic acid-decorated polypyrrole nanoparticles

Tuan Hiep Tran et al.

NANOMEDICINE (2017)

Article Chemistry, Multidisciplinary

Near-Infrared Triggered Release of uPA from Nanospheres for Localized Hyperthermia-Enhanced Thrombolysis

Xiaolei Wang et al.

ADVANCED FUNCTIONAL MATERIALS (2017)

Article Hematology

Molecular Imaging of Atherothrombotic Diseases Seeing Is Believing

Xiaowei Wang et al.

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2017)

Article Engineering, Biomedical

Platelet microparticle-inspired clot-responsive nanomedicine for targeted fibrinolysis

Christa L. Pawlowski et al.

BIOMATERIALS (2017)

Article Chemistry, Multidisciplinary

Fibrin-Targeted and H2O2-Responsive Nanoparticles as a Theranostics for Thrombosed Vessels

Changsun Kang et al.

ACS NANO (2017)

Article Nanoscience & Nanotechnology

Hydrophobic IR-780 Dye Encapsulated in cRGD-Conjugated Solid Lipid Nanoparticles for NIR Imaging-Guided Photothermal Therapy

Ye Kuang et al.

ACS APPLIED MATERIALS & INTERFACES (2017)

Article Hematology

Platelet Control of Fibrin Distribution and Microelasticity in Thrombus Formation Under Flow

Frauke Swieringa et al.

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2016)

Review Hematology

Engineering of plasminogen activators for targeting to thrombus and heightening thrombolytic efficacy

S. Absar et al.

JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2015)

Article Biochemistry & Molecular Biology

Near infrared light induces post-translational modifications of human red blood cell proteins

Tomasz Walski et al.

PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES (2015)

Article Cardiac & Cardiovascular Systems

Towards Effective and Safe Thrombolysis and Thromboprophylaxis

Xiaowei Wang et al.

CIRCULATION RESEARCH (2014)

Article Multidisciplinary Sciences

Identification of platelet function defects by multi-parameter assessment of thrombus formation

Susanne M. de Witt et al.

NATURE COMMUNICATIONS (2014)

Article Engineering, Biomedical

Sentinel lymph node mapping by a near-infrared fluorescent heptamethine dye

Chao Zhang et al.

BIOMATERIALS (2010)

Article Multidisciplinary Sciences

Triggers, targets and treatments for thrombosis

Nigel Mackman

NATURE (2008)

Article Biochemistry & Molecular Biology

Mechanism of collagen activation in human platelets

DE Roberts et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2004)