Publishing Translational Research of Nanomedicine in ACS Nano

Editorial Material Chemistry, Multidisciplinary

Digital Nanomedicine: A New Frontier for Drug Development

Dean Ho

ACS NANO (2022)

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Editorial Material Chemistry, Multidisciplinary

Nano for CRISPR

Tony Hu et al.

ACS NANO (2022)

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Article Nanoscience & Nanotechnology

Direct patterning of colloidal quantum dots with adaptable dual-ligand surface

Donghyo Hahm et al.

Summary: A dual-ligand passivation system enables quantum dots to be universally compatible with solution-based patterning techniques, allowing for the integration of luminescent quantum dot films into photonic devices. This approach offers high resolution, non-destructive patterning, and cost-effectiveness, and can be applied to various commercial photonics applications.

NATURE NANOTECHNOLOGY (2022)

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Article Chemistry, Multidisciplinary

Caffeic Acid Modified Nanomicelles Inhibit Articular Cartilage Deterioration and Reduce Disease Severity in Experimental Inflammatory Arthritis

Akshay Vyawahare et al.

Summary: The study found that the combination of 9AA and CA conjugated nanomicelles (9AA-NMs) can inhibit inflammation and alleviate symptoms of rheumatoid arthritis, such as joint damage, bone erosion, and swelling. The therapeutic effect is likely due to the simultaneous inhibition of NF-kappa B by 9AA and the suppression of HIF-1 alpha by NR4A1 activation. This combined treatment significantly enhances the therapeutic efficacy of 9AA-NMs and reduces the severity of inflammatory arthritis.

ACS NANO (2022)

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Editorial Material Chemistry, Multidisciplinary

What Do We Mean When We Say Nanomedicine?

Luis M. Liz-Marzan et al.

ACS NANO (2022)

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Article Chemistry, Multidisciplinary

Algorithmic Design of 3D Wireframe RNA Polyhedra

Antti Elonen et al.

Summary: This study presents an algorithmic design process and software pipeline for rendering 3D wireframe polyhedral nanostructures in single-stranded RNA. Users can create models of desired nanostructures using standard 3D graphic design software, and the pipeline generates corresponding RNA nucleotide sequences for experimental folding in the laboratory.

ACS NANO (2022)

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Article Chemistry, Multidisciplinary

Surfactant-Assisted Isolation of Small-Diameter Boron-Nitride Nanotubes for Molding One-Dimensional van der Waals Heterostructures

Shinpei Furusawa et al.

Summary: In this study, well-dispersed boron-nitride nanotube (BNNT) templates were successfully prepared via surfactant dispersions, and comprehensive microscopic analyses were performed. Statistical analysis revealed the enrichment of small-diameter double-walled BNNTs through chemical peeling. Moreover, it was demonstrated that the isolated BNNTs can template the coaxial growth of carbon and MoS2 nanotubes.

ACS NANO (2022)

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Article Multidisciplinary Sciences

Development of intravenously administered synthetic RNA virus immunotherapy for the treatment of cancer

Edward M. Kennedy et al.

Summary: The synthetic RNA virus platform provides a new approach for repeated intravenous administration of viral immunotherapy, by formulating synthetic RNA viruses within lipid nanoparticles, showing anti-tumor efficacy even in the presence of neutralizing antibodies against the virus.

NATURE COMMUNICATIONS (2022)

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Editorial Material Chemistry, Multidisciplinary

A Virtual Issue on Nanomedicine

Wolfgang J. Parak et al.

ACS NANO (2021)

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Article Chemistry, Multidisciplinary

Design of SARS-CoV-2 hFc-Conjugated Receptor-Binding Domain mRNA Vaccine Delivered via Lipid Nanoparticles

Uri Elia et al.

Summary: This study presents the design of an mRNA vaccine based on lipid nanoparticles (LNPs) encapsulated SARS-CoV-2 human Fc-conjugated receptor-binding domain (RBD-hFc), demonstrating its potential to induce strong immune responses and produce neutralizing antibodies, making it a promising candidate for a COVID-19 vaccine.

ACS NANO (2021)

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Article Chemistry, Multidisciplinary

Bioinspired Theranostic Coordination Polymer Nanoparticles for Intranasal Dopamine Replacement in Parkinson's Disease

Javier Garcia-Pardo et al.

Summary: This study demonstrates the synthesis of neuromelanin bioinspired polymeric nanoparticles for encapsulating DA with high loading efficiency. In vitro, the DA-NCPs showed lower toxicity and enhanced uptake by dopaminergic cells compared to free DA. In vivo, nasal administration of DA-NCPs increased striatal DA levels and reduced apomorphine-induced rotations, highlighting the potential of nanostructured DA for DA-replacement therapy.

ACS NANO (2021)

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Editorial Material Chemistry, Multidisciplinary