4.4 Article

Structural Insight for Roles of DR5 Death Domain Mutations on Oligomerization of DR5 Death Domain-FADD Complex in the Death-Inducing Signaling Complex Formation: A Computational Study

Related references

Note: Only part of the references are listed.
Review Pharmacology & Pharmacy

The MM/PBSA and MM/GBSA methods to estimate ligand-binding affinities

Samuel Genheden et al.

EXPERT OPINION ON DRUG DISCOVERY (2015)

Article Biochemistry & Molecular Biology

TCS: A New Multiple Sequence Alignment Reliability Measure to Estimate Alignment Accuracy and Improve Phylogenetic Tree Reconstruction

Jia-Ming Chang et al.

MOLECULAR BIOLOGY AND EVOLUTION (2014)

Review Biochemistry & Molecular Biology

TRAIL on trial: preclinical advances in cancer therapy

Daniel W. Stuckey et al.

TRENDS IN MOLECULAR MEDICINE (2013)

Article Cell Biology

Caspase Functions in Cell Death and Disease

David R. McIlwain et al.

COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2013)

Article Biochemistry & Molecular Biology

Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL) Induces Death Receptor 5 Networks That Are Highly Organized

Christopher C. Valley et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2012)

Article Chemistry, Physical

MMPBSA.py: An Efficient Program for End-State Free Energy Calculations

Bill R. Miller et al.

JOURNAL OF CHEMICAL THEORY AND COMPUTATION (2012)

Review Biochemistry & Molecular Biology

Caspase-8 and Bid: Caught in the act between death receptors and mitochondria

Chahrazade Kantari et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2011)

Review Pharmacology & Pharmacy

Targeting Trail Towards the Clinic

Devalingam Mahalingam et al.

CURRENT DRUG TARGETS (2011)

Article Biochemistry & Molecular Biology

Trifluoperazine regulation of calmodulin binding to Fas: A computational study

Di Pan et al.

PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2011)

Review Oncology

TRAIL receptor signalling and modulation: Are we on the right TRAIL?

Devalingam Mahalingam et al.

CANCER TREATMENT REVIEWS (2009)

Article Multidisciplinary Sciences

The Fas-FADD death domain complex structure unravels signalling by receptor clustering

Fiona L. Scott et al.

NATURE (2009)

Review Endocrinology & Metabolism

The role for endoplasmic reticulum stress in diabetes mellitus

Decio L. Eizirik et al.

ENDOCRINE REVIEWS (2008)

Article Biotechnology & Applied Microbiology

Apomab: An agonist monoclonal antibody directed against Death Receptor 5/TRAIL-Receptor 2 for use in the treatment of solid tumors

D. Ross Camidge

EXPERT OPINION ON BIOLOGICAL THERAPY (2008)

Review Cell Biology

Apoptosis: controlled demolition at the cellular level

Rebecca C. Taylor et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2008)

Article Biochemistry & Molecular Biology

Effect of altered glycosylation on the structure of the I-like domain of β1 integrin: A molecular dynamics study

Yuemin Liu et al.

PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2008)

Article Biochemistry & Molecular Biology

Tumor-derived mutations in the TRAIL receptor DR5 inhibit TRAIL signaling through the DR4 receptor by competing for ligand binding

Lianghua Bin et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

Article Biochemistry & Molecular Biology

ProSA-web: interactive web service for the recognition of errors in three-dimensional structures of proteins

Markus Wiederstein et al.

NUCLEIC ACIDS RESEARCH (2007)

Review Pathology

Apoptosis: A review of programmed cell death

Susan Elmore

TOXICOLOGIC PATHOLOGY (2007)

Article Cell Biology

How the headpiece hinge angle is opened: new insights into the dynamics of integrin activation

Eileen Puklin-Faucher et al.

JOURNAL OF CELL BIOLOGY (2006)

Article Biochemistry & Molecular Biology

The structure of FADD and its mode of interaction with procaspase-8

Paul E. Carrington et al.

MOLECULAR CELL (2006)

Review Chemistry, Multidisciplinary

The Amber biomolecular simulation programs

DA Case et al.

JOURNAL OF COMPUTATIONAL CHEMISTRY (2005)

Article Biochemical Research Methods

ProRule: a new database containing functional and structural information on PROSITE profiles

CJA Sigrist et al.

BIOINFORMATICS (2005)

Review Oncology

Promoting apoptosis as a strategy for cancer drug discovery

SW Fesik

NATURE REVIEWS CANCER (2005)

Review Cell Biology

Death receptor-induced cell killing

A Thorburn

CELLULAR SIGNALLING (2004)

Review Oncology

Death receptor signals to mitochondria

R Khosravi-Far et al.

CANCER BIOLOGY & THERAPY (2004)

Article Chemistry, Multidisciplinary

UCSF chimera - A visualization system for exploratory research and analysis

EF Pettersen et al.

JOURNAL OF COMPUTATIONAL CHEMISTRY (2004)

Review Oncology

Cell surface death receptor signaling in normal and cancer cells

N Özören et al.

SEMINARS IN CANCER BIOLOGY (2003)

Article Biochemistry & Molecular Biology

A unified model for apical caspase activation

KM Boatright et al.

MOLECULAR CELL (2003)

Article Biochemistry & Molecular Biology

Insights into the regulatory mechanism for caspase-8 activation

M Donepudi et al.

MOLECULAR CELL (2003)

Review Biochemistry & Molecular Biology

The CD95(APO-1/Fas) DISC and beyond

ME Peter et al.

CELL DEATH AND DIFFERENTIATION (2003)

Article Gastroenterology & Hepatology

Inactivating mutations of KILLER/DR5 gene in gastric cancers

WS Park et al.

GASTROENTEROLOGY (2001)

Article Multidisciplinary Sciences

Electrostatics of nanosystems: Application to microtubules and the ribosome

NA Baker et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)

Article Biochemistry & Molecular Biology

Tumoricidal activity of a novel anti-human DR5 monoclonal antibody without hepatocyte cytotoxicity

K Ichikawa et al.

NATURE MEDICINE (2001)

Article Biochemistry & Molecular Biology

Death domain mutagenesis of KILLER/DR5 reveals residues critical for apoptotic signaling

ER McDonald et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2001)

Article Biochemistry & Molecular Biology

T-Coffee: A novel method for fast and accurate multiple sequence alignment

C Notredame et al.

JOURNAL OF MOLECULAR BIOLOGY (2000)

Article Biochemistry & Molecular Biology

A unique zinc-binding site revealed by a high-resolution X-ray structure of homotrimeric Apo2L/TRAIL

SG Hymowitz et al.

BIOCHEMISTRY (2000)

Review Oncology

Apoptosis in cancer

SW Lowe et al.

CARCINOGENESIS (2000)