Related references
Note: Only part of the references are listed.Mutations enhancing selectivity of antitumor cytokine TRAIL to DR5 receptor increase its cytotoxicity against tumor cells
M. E. Gasparian et al.
BIOCHEMISTRY-MOSCOW (2015)
The MM/PBSA and MM/GBSA methods to estimate ligand-binding affinities
Samuel Genheden et al.
EXPERT OPINION ON DRUG DISCOVERY (2015)
Molecular Insight into the Effect of Lipid Bilayer Environments on Thrombospondin-1 and Calreticulin Interactions
Lingyun Wang et al.
BIOCHEMISTRY (2014)
Safety, pharmacokinetics, and pharmacodynamics of the DR5 antibody LBY135 alone and in combination with capecitabine in patients with advanced solid tumors
Sunil Sharma et al.
INVESTIGATIONAL NEW DRUGS (2014)
TCS: A New Multiple Sequence Alignment Reliability Measure to Estimate Alignment Accuracy and Improve Phylogenetic Tree Reconstruction
Jia-Ming Chang et al.
MOLECULAR BIOLOGY AND EVOLUTION (2014)
Structural insight for the roles of fas death domain binding to fadd and oligomerization degree of the fas-fadd complex in the death-inducing signaling complex formation: A computational study
Qi Yan et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2013)
TRAIL on trial: preclinical advances in cancer therapy
Daniel W. Stuckey et al.
TRENDS IN MOLECULAR MEDICINE (2013)
Caspase Functions in Cell Death and Disease
David R. McIlwain et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2013)
Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL) Induces Death Receptor 5 Networks That Are Highly Organized
Christopher C. Valley et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
MMPBSA.py: An Efficient Program for End-State Free Energy Calculations
Bill R. Miller et al.
JOURNAL OF CHEMICAL THEORY AND COMPUTATION (2012)
Molecular and Structural Insight into the Role of Key Residues of Thrombospondin-1 and Calreticulin in Thrombospondin-1-Calreticulin Binding
Qi Yan et al.
BIOCHEMISTRY (2011)
Caspase-8 and Bid: Caught in the act between death receptors and mitochondria
Chahrazade Kantari et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2011)
Targeting Trail Towards the Clinic
Devalingam Mahalingam et al.
CURRENT DRUG TARGETS (2011)
Trifluoperazine regulation of calmodulin binding to Fas: A computational study
Di Pan et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2011)
Structural Insight into the Role of Thrombospondin-1 Binding to Calreticulin in Calreticulin-Induced Focal Adhesion Disassembly
Qi Yan et al.
BIOCHEMISTRY (2010)
Role of Altered Sialylation of the I-Like Domain of β1 Integrin in the Binding of Fibronectin to β1 Integrin: Thermodynamics and Conformational Analyses
Di Pan et al.
BIOPHYSICAL JOURNAL (2010)
Multivalent DR5 Peptides Activate the TRAIL Death Pathway and Exert Tumoricidal Activity
Valeria Pavet et al.
CANCER RESEARCH (2010)
TRAIL receptor signalling and modulation: Are we on the right TRAIL?
Devalingam Mahalingam et al.
CANCER TREATMENT REVIEWS (2009)
The Fas-FADD death domain complex structure unravels signalling by receptor clustering
Fiona L. Scott et al.
NATURE (2009)
Conformation and Free Energy Analyses of the Complex of Calcium-Bound Calmodulin and the Fas Death Domain
Jonathan D. Suever et al.
BIOPHYSICAL JOURNAL (2008)
Molecular dynamics simulations of asymmetric NaCl and KCl solutions separated by phosphatidylcholine bilayers:: Potential drops and structural changes induced by strong Na+-lipid interactions and finite size effects
Sun-Joo Lee et al.
BIOPHYSICAL JOURNAL (2008)
The role for endoplasmic reticulum stress in diabetes mellitus
Decio L. Eizirik et al.
ENDOCRINE REVIEWS (2008)
Apomab: An agonist monoclonal antibody directed against Death Receptor 5/TRAIL-Receptor 2 for use in the treatment of solid tumors
D. Ross Camidge
EXPERT OPINION ON BIOLOGICAL THERAPY (2008)
Ligand-based targeting of apoptosis in cancer: The potential of recombinant human apoptosis ligand 2/tumor necrosis factor-related apoptosis-inducing ligand (rhApo2L/TRAIL)
Avi Ashkenazi et al.
JOURNAL OF CLINICAL ONCOLOGY (2008)
Treating metastatic solid tumors with bortezomib and a tumor necrosis factor-related apoptosis-inducing ligand receptor agonist antibody
Anil Shanker et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2008)
Apoptosis: controlled demolition at the cellular level
Rebecca C. Taylor et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2008)
Effect of altered glycosylation on the structure of the I-like domain of β1 integrin: A molecular dynamics study
Yuemin Liu et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2008)
Tumor-derived mutations in the TRAIL receptor DR5 inhibit TRAIL signaling through the DR4 receptor by competing for ligand binding
Lianghua Bin et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
ProSA-web: interactive web service for the recognition of errors in three-dimensional structures of proteins
Markus Wiederstein et al.
NUCLEIC ACIDS RESEARCH (2007)
Apoptosis: A review of programmed cell death
Susan Elmore
TOXICOLOGIC PATHOLOGY (2007)
How the headpiece hinge angle is opened: new insights into the dynamics of integrin activation
Eileen Puklin-Faucher et al.
JOURNAL OF CELL BIOLOGY (2006)
The structure of FADD and its mode of interaction with procaspase-8
Paul E. Carrington et al.
MOLECULAR CELL (2006)
A novel anti-human DR5 monoclonal antibody with tumoricidal activity induces caspase-dependent and caspase-independent cell death
YB Guo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
The Amber biomolecular simulation programs
DA Case et al.
JOURNAL OF COMPUTATIONAL CHEMISTRY (2005)
ProRule: a new database containing functional and structural information on PROSITE profiles
CJA Sigrist et al.
BIOINFORMATICS (2005)
Promoting apoptosis as a strategy for cancer drug discovery
SW Fesik
NATURE REVIEWS CANCER (2005)
Molecular dynamics simulations of salicylate effects on the micro- and mesoscopic properties of a dipalmitoylphosphatidylcholine bilayer
YH Song et al.
BIOCHEMISTRY (2005)
Receptor-selective mutants of apoptosis-inducing ligand 2/tumor necrosis factor-related apoptosis-inducing ligand reveal a greater contribution
RF Kelley et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Apo2 ligand/tumor necrosis factor-related apoptosis-inducing ligand cooperates with chemotherapy to inhibit orthotopic lung tumor growth and improve survival
H Jin et al.
CANCER RESEARCH (2004)
Death receptor signals to mitochondria
R Khosravi-Far et al.
CANCER BIOLOGY & THERAPY (2004)
UCSF chimera - A visualization system for exploratory research and analysis
EF Pettersen et al.
JOURNAL OF COMPUTATIONAL CHEMISTRY (2004)
Cell surface death receptor signaling in normal and cancer cells
N Özören et al.
SEMINARS IN CANCER BIOLOGY (2003)
A unified model for apical caspase activation
KM Boatright et al.
MOLECULAR CELL (2003)
Insights into the regulatory mechanism for caspase-8 activation
M Donepudi et al.
MOLECULAR CELL (2003)
Are oxidative stress-activated signaling pathways mediators of insulin resistance and beta-cell dysfunction?
JL Evans et al.
DIABETES (2003)
The CD95(APO-1/Fas) DISC and beyond
ME Peter et al.
CELL DEATH AND DIFFERENTIATION (2003)
Defining characteristics of Types I and II apoptotic cells in response to TRAIL
N Özören et al.
NEOPLASIA (2002)
Targeting death and decoy receptors of the tumour-necrosis factor superfamily
A Ashkenazi
NATURE REVIEWS CANCER (2002)
Inactivating mutations of KILLER/DR5 gene in gastric cancers
WS Park et al.
GASTROENTEROLOGY (2001)
Electrostatics of nanosystems: Application to microtubules and the ribosome
NA Baker et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Tumoricidal activity of a novel anti-human DR5 monoclonal antibody without hepatocyte cytotoxicity
K Ichikawa et al.
NATURE MEDICINE (2001)
Death domain mutagenesis of KILLER/DR5 reveals residues critical for apoptotic signaling
ER McDonald et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Crystal structure of TRAIL-DR5 complex identifies a critical role of the unique frame insertion in conferring recognition specificity
SS Cha et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
T-Coffee: A novel method for fast and accurate multiple sequence alignment
C Notredame et al.
JOURNAL OF MOLECULAR BIOLOGY (2000)
A unique zinc-binding site revealed by a high-resolution X-ray structure of homotrimeric Apo2L/TRAIL
SG Hymowitz et al.
BIOCHEMISTRY (2000)