Journal
JOURNAL OF MOLECULAR DIAGNOSTICS
Volume 18, Issue 6, Pages 789-802Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.jmoldx.2016.07.007
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The performance of matrix-assisted Laser desorption ionization time-of-flight mass spectrometry (MS) for routine bacterial and yeast identification as well as direct-from-blood culture bottle identification has been thoroughly evaluated in the peer-reviewed literature. Microbiologists are now moving beyond these methods to apply MS to other areas of the diagnostic process. This review discusses the emergence of advanced matrix-assisted Laser desorption ionization time-of-flight MS applications, including the identification of filamentous fungi and mycobacteria and the current and future state of antimicrobial resistance testing.
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