Cube-octameric silsesquioxane-mediated cargo copper Schiff base for efficient click reaction in aqueous media

The azide-alkyne cycloaddition reaction was investigated under catalytic conditions involving a copper(II)-polyhedral oligomeric silsesquioxane (POSS)-bridged Schiff base. This material demonstrated a high catalytic activity in organic synthesis of 1,4-triazoles. No additive such as a base or a reductant was required. Finally, recoverability and reusability of the POSS-bridged Schiff base-Cu(II) catalyst was analyzed. (C) 2015 Elsevier B.V. All rights reserved.