4.5 Article

Adaptive Behavior in Young Autistic Children: Associations with Irritability and ADHD Symptoms

Journal

Publisher

SPRINGER/PLENUM PUBLISHERS
DOI: 10.1007/s10803-022-05753-2

Keywords

Adaptive Behavior; Irritability; Attention-Deficit; Hyperactivity Disorder (ADHD); Autism Spectrum Disorder; Preschool Age

Funding

  1. Autism Center of Excellence (ACE) grants from the Eunice Kennedy Shriver National Institute for Child Health and Human Development (NICHD) [P50-HD093074, U01-HD073984]
  2. Department of Defense Office of the Assistant Secretary of Defense for Health Affairs through the Autism Research Program [W81XWH-14-1-0526]

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This study examined the relationships between irritability, ADHD symptoms, and adaptive behavior in autistic children. The results suggest a link between higher levels of irritability and differences in social adaptive behavior.
Attention-deficit/hyperactivity disorder (ADHD) symptoms affect 40-60% of autistic children and have been linked to differences in adaptive behavior. It is unclear whether adaptive behavior in autistic youth is directly impacted by co-occurring ADHD symptoms or by another associated feature of both autism and ADHD, such as increased irritability. The current study examined relationships between irritability, ADHD symptoms, and adaptive behavior in 3- to 7-year-old autistic children. Results suggest that, after adjusting for co-occurring ADHD symptoms, higher levels of irritability are associated with differences in social adaptive behavior specifically. Understanding relationships between irritability, ADHD, and adaptive behavior in autistic children is critical because measures of adaptive behavior, such as the Vineland Scales of Adaptive Functioning, are often used as a proxy for global functioning, as well as for developing intervention plans and measuring outcomes as primary endpoints in clinical trials.

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