Iron-Organic Framework Nanoparticle-Supported Tungstosilicic Acid as a Catalyst for the Biginelli Reaction

In this work, a metal-organic framework with an octahedral morphology supported by a tungstosilicic acid (TSA) nanocatalyst has been successfully synthesized through a post-synthetic modification approach and referred to as TSA/MIL-88B. The as-prepared catalyst was efficiently obtained from Biginelli reactions among benzaldehyde, urea, and 1,3-dicarbonyl compound. Depending on the synergistic effect of exposed metal iron sites and the supported Bronsted acid sites, the hybrid materials exhibited high catalytic activity. Additionally, the environmentally friendly nano-catalyst could be recycled seven times with a little reduction in the catalytic performance. This study also provides a way for the application of such porous organic polymer functionalization in organic synthesis.

Automated summary

In this study, a metal-organic framework with an octahedral morphology supported by a tungstosilicic acid (TSA) nanocatalyst was successfully synthesized. The hybrid material showed high catalytic activity due to the synergistic effect of exposed metal iron sites and the supported Bronsted acid sites. The environmentally friendly nano-catalyst could be recycled multiple times without significant loss in catalytic performance. This study also provides insights into the application of porous organic polymer functionalization in organic synthesis.