Pharmacologic Ascorbic Acid as Early Therapy for Hospitalized Patients with COVID-19: A Randomized Clinical Trial (vol 12, 453, 2022)

Summary: This randomized controlled trial investigated the impact of ascorbic acid on early clinical outcomes in COVID-19 patients. The results showed that ascorbic acid may be beneficial in reducing the use of supplemental oxygen, bronchodilators, and shortening the length of hospital stay in hospitalized patients. However, the beneficial effects of ascorbic acid diminished over the course of hospitalization. Future research should focus on the potential early benefits of ascorbic acid in hospitalized patients.