4.7 Article

A Detection-Service-Mobile Three-Terminal Software Platform for Point-of-Care Infectious Disease Detection System

Journal

BIOSENSORS-BASEL
Volume 12, Issue 9, Pages -

Publisher

MDPI
DOI: 10.3390/bios12090684

Keywords

point-of-care testing; three-terminal software; geographic information system; infectious disease warning; machine learning

Funding

  1. National Natural Science Foundation of China [62071119, 81902153]
  2. Hunan Urgency Project [2020SK3005]
  3. Hunan Key RD Projects [2021SK2003]
  4. State Key Laboratory of Oral Diseases [SKLOD2022OF05]

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This study designs a detection-service-mobile three-terminal system for the control of diagnostic instruments and comprehensive data management. By using machine learning to classify enlarged curves and combining with a geographic information system, the visual display of nucleic acid amplification detection results and early warning of infectious diseases are achieved.
The traditional infectious disease detection process is cumbersome, and there is only a single application scenario. In recent years, with the development of the medical industry and the impact of the epidemic situation, the number of infectious disease detection instruments based on nursing point detection has been increasing. Due to this trend, many detection instruments and massive detection data urgently need to be managed. In addition, the experiment failed due to the abnormal fluorescence curve generated by a human operator or sample impurities. Finally, the geographic information system has also played an active role in spreading and preventing infectious diseases; this paper designs a detection-service-mobile three-terminal system to realize the control of diagnostic instruments and the comprehensive management of data. Machine learning is used to classify the enlarged curve and calculate the cycle threshold of the positive curve; combined with a geographic information system, the detection results are marked on the mobile terminal map to realize the visual display of the positive results of nucleic acid amplification detection and the early warning of infectious diseases. In the research, applying this system to portable field pathogen detection is feasible and practical.

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