Related references
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Article
Infectious Diseases
Isabel Bergeri et al.
Summary: This article introduces the rapid development and global promotion of UNITY studies during the COVID-19 pandemic to support early investigations for appropriate public health actions. Results show that the widespread adoption of UNITY protocols across all WHO regions addresses subnational and national needs to support local public health decision-making to prevent and control the pandemic.
INFLUENZA AND OTHER RESPIRATORY VIRUSES
(2022)
Article
Immunology
Alexander C. Dowell et al.
Summary: Children exhibit stronger and more sustained immune responses to SARS-CoV-2 infection, with higher levels of antibodies and T cell responses compared to adults, and the ability to neutralize various viral variants. These findings suggest that children may have a more robust immune system against the virus, potentially providing insight into the milder clinical presentation of SARS-CoV-2 in most children.
Article
Biochemistry & Molecular Biology
Yu Gao et al.
Summary: This study found that SARS-CoV-2 spike-specific CD4(+) and CD8(+) T cells induced by prior infection or BNT162b2 vaccination provide extensive immune coverage against the Omicron variant. Additionally, T cells induced by BNT162b2 vaccination exhibit higher cross-reactivity to the Omicron variant compared to T cells induced by prior SARS-CoV-2 infection.
Editorial Material
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Mandeep Dhaliwal et al.
BMJ-BRITISH MEDICAL JOURNAL
(2022)
Editorial Material
Immunology
Nathan Duarte et al.
Summary: Population-level immune surveillance, including serosurveys, is crucial for public health decision-making during a pandemic. Serosurveys can provide valuable information on the prevalence of antibodies, distinguish infection and vaccine-induced immune responses, and guide vaccine distribution and booster dose needs.
OPEN FORUM INFECTIOUS DISEASES
(2022)
Review
Virology
Master R. O. Chisale et al.
Summary: A study estimated the seroprevalence of anti-SARS-CoV-2 antibodies in residents of African countries, finding a pooled seroprevalence of 22% with significant heterogeneity among studies. The highest seroprevalence was found in Central Africa, and factors such as the number of days between the first reported COVID-19 case and seroprevalence study, as well as gender and age of participants, influenced seropositivity. Continued surveillance is needed to understand Africa's progress towards herd immunity.
REVIEWS IN MEDICAL VIROLOGY
(2022)
Article
Respiratory System
M. Paleker et al.
Summary: Research revealed that during the lockdown period, nearly 45% of COVID-19 cases in the workplace were asymptomatic. This indicates the significant impact of asymptomatic carriers on the pandemic trajectory, advocating for the quarantine of all close contacts of COVID-19 cases regardless of symptoms.
PUBLIC HEALTH ACTION
(2021)
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Medicine, General & Internal
Jonathan Mandolo et al.
Summary: The study found that Malawi experienced two waves of SARS-CoV-2 epidemic, with widespread exposure and high antibody detection rates in both urban and rural areas. The first wave sera showed higher neutralization activity against the original variant, while the second wave sera exhibited higher neutralization activity against the Beta variant. Blantyre and Mzuzu also showed signs of a third pandemic wave.
Article
Infectious Diseases
For Yue Tso et al.
Summary: The study found a higher prevalence of SARS-CoV-2 cross-reactive antibodies in pre-pandemic plasma samples from SSA compared to the USA, indicating potential cross-protection due to prior exposure to other coronaviruses in SSA. The detection of nucleocapsid proteins from HCoV-NL63 and HCoV-229E in most samples suggests these viruses as the likely sources of cross-reactive antibodies against SARS-CoV-2. The low incidence of SARS-CoV-2 infection and disease in SSA may be correlated with pre-pandemic serological cross-recognition of HCoVs, which are more prevalent in SSA than the USA.
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
(2021)
Article
Virology
Rodrigo Borrega et al.
Summary: Research on the serological responses of Sierra Leoneans to coronaviruses suggests that pre-existing immunity from previous exposures may contribute to the lower COVID-19 caseloads and deaths in the country. This immunity is likely due to cross-reactive antibodies against coronaviruses such as SARS-CoV-2, SARS-CoV, and MERS-CoV.
Review
Public, Environmental & Occupational Health
Xinhua Chen et al.
Summary: This study synthesized and evaluated a large amount of global data on SARS-CoV-2 serological surveys, revealing variations in seroprevalence among different populations and in the infection-to-case ratio across regions. Most settings have not achieved herd immunity, and insights into the true proportion of infected population can be derived from serological detection data in routine confirmation.
LANCET GLOBAL HEALTH
(2021)
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Biology
Marloes Grobben et al.
Summary: Research shows that after SARS-CoV-2 infection and vaccination, humans produce cross-reactive antibodies against multiple coronaviruses, supporting the feasibility of developing a pan-coronavirus vaccine.
Article
Public, Environmental & Occupational Health
Esayas Kebede Gudina et al.
Lancet Global Health
(2021)
Article
Microbiology
Laura C. Steinhardt et al.
Summary: Accurate SARS-CoV-2 serological assays are crucial for COVID-19 surveillance, but cross-reactivity issues were found in areas with malaria endemicity. A simple urea wash can help alleviate this cross-reactivity problem.
JOURNAL OF CLINICAL MICROBIOLOGY
(2021)
Article
Psychology, Biological
Edouard Mathieu et al.
Summary: An effective rollout of COVID-19 vaccines is crucial in ending the pandemic, and Our World in Data's vaccination dataset tracks the progress and scale of vaccine distribution globally, aiding policymakers and researchers in understanding the global vaccination efforts.
NATURE HUMAN BEHAVIOUR
(2021)
Article
Public, Environmental & Occupational Health
Humphrey Cyprian Karamagi et al.
Summary: This study proposes an approach to assess the functionality of health systems in order to help countries achieve universal health coverage goals. By conceptualizing health system functionality as a combination of four capacities, the study found that access to essential services is the weakest capacity, and funding levels are the strongest predictor of system functionality in the WHO African Region.
Article
Microbiology
Maaike J. C. van den Beld et al.
Summary: A nationwide collaborative approach in the Netherlands was employed to evaluate the performance of serological assays for SARS-CoV-2, with 41 Dutch laboratories sharing their evaluation data. This collaboration increased the efficiency of the national laboratory response and supported laboratories in their choice and implementation of assays. The aggregated performance data showed that certain immunoassays met predefined performance criteria for detecting IgG in hospitalized patients and patients with mild or asymptomatic infections.
JOURNAL OF CLINICAL MICROBIOLOGY
(2021)
Review
Multidisciplinary Sciences
Niklas Bobrovitz et al.
Summary: A systematic review and meta-analysis of 968 seroprevalence studies with 9.3 million participants from 74 countries found significant variations in SARS-CoV-2 antibody prevalence among different populations. Ethnic minorities and certain age groups were more likely to test positive for antibodies. National studies reported lower seroprevalence estimates compared to regional and local studies, with considerable variation across regions.
Article
Immunology
Kristen A. Earle et al.
Summary: The study found a strong correlation between antibody titers and efficacy when assessing different COVID-19 vaccines, supporting the use of post-immunization antibody titers as the basis for establishing a correlate of protection for COVID-19 vaccines.
Article
Psychology, Multidisciplinary
Benjamin Osayawe Ehigie et al.
Summary: Social distancing is a set of interventions aimed at preventing the spread of contagious diseases and during the COVID-19 pandemic, the term 'physical distancing' was recommended by the World Health Organization. While Africans are familiar with the concept of social distancing, applying it in pandemic situations poses challenges due to historical associations with non-infectious cases.
PSYCHOLOGICAL STUDIES
(2021)
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Demography
Olusesan Ayodeji Makinde et al.
Summary: This study assessed household sanitation and isolation capacities to understand the COVID-19 transmission risk at household level across Africa. It found significant variations in prevention capacities across countries, with households having elderly members not necessarily having the best handwashing or isolation capacity.
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LANCET INFECTIOUS DISEASES
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NEW MICROBES AND NEW INFECTIONS
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