Journal
JOURNAL OF PERSONALIZED MEDICINE
Volume 12, Issue 9, Pages -Publisher
MDPI
DOI: 10.3390/jpm12091531
Keywords
reactive oxygen species; photolysis; antimicrobial photodynamic therapy; sterilization; smear layer removal; endodontic therapy
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This article reviews the basic effects of ROS in dental medicine, especially endodontic therapy, and discusses future applications of ROS.
Reactive oxygen species (ROS) and free radicals, which have been implicated in inflammation, pain, carcinogenesis, and aging, are actually used in dental treatments such as tooth bleaching and composite resin polymerization. Recently, numerous studies have investigated the application of ROS in the medical and dental fields. In previous studies, ROS were generated intentionally through pathways such as photolysis, photocatalytic methods, and photodynamic therapy, which are used in the medical field to target cancer. In the field of dentistry, generated ROS are applied mainly for periodontal treatment and sterilization of the root canal, and its effectiveness as an antibacterial photodynamic therapy has been widely reported.. Given this background, the present article aimed to review the basic effects of ROS in dental medicine, especially endodontic therapy, and to discuss future applications of ROS.
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