4.3 Article

Comparison of the Modified-Hodge test, Carba NP test, and carbapenem inactivation method as screening methods for carbapenemase-producing Enterobacteriaceae

Journal

JOURNAL OF MICROBIOLOGICAL METHODS
Volume 128, Issue -, Pages 48-51

Publisher

ELSEVIER SCIENCE BV
DOI: 10.1016/j.mimet.2016.06.019

Keywords

Carba NP test; Carbapenemase-producing Enterobacteriaceae; Carbapenem inactivation method; Modified-Hodge test

Funding

  1. Clinical Research Grant of Tokyo Metropolitan Health and Medical Treatment Corporation Toshima Hospital

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We compared three screening methods for carbapenemase-producing Enterobacteriaceae. While the Modified Hodge test and Carba NP test produced false-negative results for OXA-48-like and mucoid NDM producers, the carbapenem inactivation method (CIM) showed positive results for these isolates. Although the CIM required cultivation time, it is well suited for general clinical laboratories. (C) 2016 Elsevier B.V. All rights reserved.

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