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Methods for Assessing Oocyte Quality: A Review of Literature

Journal

BIOMEDICINES
Volume 10, Issue 9, Pages -

Publisher

MDPI
DOI: 10.3390/biomedicines10092184

Keywords

oocytes; quality; morphology; genetics; polarized light; follicular fluid; apoptosis

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This paper presents potential non-invasive and invasive techniques to assess oocyte quality, including morphological, genetic, molecular, and apoptosis methods. These techniques play an important role in improving the assessment of oocyte quality in infertility patients, but most of them are invasive and not suitable for routine use.
The rate of infertility continues to rise in the world for several reasons, including the age of conception and current lifestyle. We list in this paper potential non-invasive and invasive techniques to assess oocyte quality. We searched the database PubMed using the terms oocytes AND quality AND evaluation. In the first part, we study the morphological criteria, compartment by compartment, to then focus in a second part on more objective techniques such as genetics, molecular, apoptosis, or human follicular fluid that contain biologically active molecules. The main criteria used to assess oocyte quality are morphological; however, several other techniques have been studied in women to improve oocyte quality assessment, but most of them are invasive and not usable in routine.

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