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Selective Nanovector Mediated Treatment of Activated Proinflammatory Microglia/Macrophages in Spinal Cord Injury
Simonetta Papa et al.
ACS NANO (2013)
Effective long-term immunosuppression in rats by subcutaneously implanted sustained-release tacrolimus pellet: Effect on spinally grafted human neural precursor survival
Juraj Sevc et al.
EXPERIMENTAL NEUROLOGY (2013)
Caudalized human iPSC-derived neural progenitor cells produce neurons and glia but fail to restore function in an early chronic spinal cord injury model
Samuel E. Nutt et al.
EXPERIMENTAL NEUROLOGY (2013)
B Cell Activation Is Regulated by the Stiffness Properties of the Substrate Presenting the Antigens
Zhengpeng Wan et al.
JOURNAL OF IMMUNOLOGY (2013)
Glial Scar Borders Are Formed by Newly Proliferated, Elongated Astrocytes That Interact to Corral Inflammatory and Fibrotic Cells via STAT3-Dependent Mechanisms after Spinal Cord Injury
Ina B. Wanner et al.
JOURNAL OF NEUROSCIENCE (2013)
Cytokines and Chemokines at the Crossroads of Neuroinflammation, Neurodegeneration, and Neuropathic Pain
Geeta Ramesh et al.
MEDIATORS OF INFLAMMATION (2013)
Effect of topography of an electrospun nanofiber on modulation of activity of primary rat astrocytes
Seul Ki Min et al.
NEUROSCIENCE LETTERS (2013)
Modulation of macrophage phenotype by cell shape
Frances Y. McWhorter et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Managing Inflammation after Spinal Cord Injury through Manipulation of Macrophage Function
Yi Ren et al.
NEURAL PLASTICITY (2013)
The effects of intrathecal injection of a hyaluronan-based hydrogel on inflammation, scarring and neurobehavioural outcomes in a rat model of severe spinal cord injury associated with arachnoiditis
James W. Austin et al.
BIOMATERIALS (2012)
The effects of substrate stiffness on the in vitro activation of macrophages and in vivo host response to poly(ethylene glycol)-based hydrogels
Anna K. Blakney et al.
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A (2012)
Substrate Rigidity Regulates Human T Cell Activation and Proliferation
Roddy S. O'Connor et al.
JOURNAL OF IMMUNOLOGY (2012)
High molecular weight hyaluronan reduces lipopolysaccharide mediated microglial activation
James W. Austin et al.
JOURNAL OF NEUROCHEMISTRY (2012)
Blockade of interleukin-6 signaling inhibits the classic pathway and promotes an alternative pathway of macrophage activation after spinal cord injury in mice
Alexander Rodriguez Guerrero et al.
JOURNAL OF NEUROINFLAMMATION (2012)
The Systemic Inflammatory Response after Spinal Cord Injury in the Rat Is Decreased by α4β1 Integrin Blockade
Feng Bao et al.
JOURNAL OF NEUROTRAUMA (2012)
CD11d Antibody Treatment Improves Recovery in Spinal Cord-Injured Mice
Nicole M. Geremia et al.
JOURNAL OF NEUROTRAUMA (2012)
Mitochondria, calcium-dependent neuronal death and neurodegenerative disease
Michael R. Duchen
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2012)
Epidemiology of traumatic cervical spinal cord injury in Tianjin, China
Q. Wu et al.
SPINAL CORD (2012)
The Epidemiology of Traumatic Spinal Cord Injury in British Columbia, Canada
Brian Lenehan et al.
SPINE (2012)
Adoptive transfer of Th1-conditioned lymphocytes promotes axonal remodeling and functional recovery after spinal cord injury
H. Ishii et al.
CELL DEATH & DISEASE (2012)
Herpes Simplex Virus Vector-Mediated Expression of Interleukin-10 Reduces Below-Level Central Neuropathic Pain After Spinal Cord Injury
Darryl Lau et al.
NEUROREHABILITATION AND NEURAL REPAIR (2012)
Trends in New Injuries, Prevalent Cases, and Aging With Spinal Cord Injury
Michael J. DeVivo et al.
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION (2011)
Effect of Electrospun Fiber Diameter and Alignment on Macrophage Activation and Secretion of Proinflammatory Cytokines and Chemokines
Enrica Saino et al.
BIOMACROMOLECULES (2011)
Neuroprotective and growth-promoting effects of bone marrow stromal cells after cervical spinal cord injury in adult rats
Liudmila N. Novikova et al.
CYTOTHERAPY (2011)
Spinal cord injury therapies in humans: an overview of current clinical trials and their potential effects on intrinsic CNS macrophages
John C. Gensel et al.
EXPERT OPINION ON THERAPEUTIC TARGETS (2011)
High molecular weight hyaluronic acid limits astrocyte activation and scar formation after spinal cord injury
Zin Z. Khaing et al.
JOURNAL OF NEURAL ENGINEERING (2011)
Ion Channel Blockers and Spinal Cord Injury
Wang-Mi Liu et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2011)
Human Spinal Cord Injury Causes Specific Increases in Surface Expression of Beta Integrins on Leukocytes
Feng Bao et al.
JOURNAL OF NEUROTRAUMA (2011)
Prevention of Both Neutrophil and Monocyte Recruitment Promotes Recovery after Spinal Cord Injury
Sang Mi Lee et al.
JOURNAL OF NEUROTRAUMA (2011)
MicroRNA-124 promotes microglia quiescence and suppresses EAE by deactivating macrophages via the C/EBP-alpha-PU.1 pathway
Eugene D. Ponomarev et al.
NATURE MEDICINE (2011)
Repertoire of microglial and macrophage responses after spinal cord injury
Samuel David et al.
NATURE REVIEWS NEUROSCIENCE (2011)
Nerve Growth Factor in Cancer Cell Death and Survival
Niamh Molloy et al.
Cancers (2011)
Tissue engineering tools for modulation of the immune response
Ryan M. Boehler et al.
BIOTECHNIQUES (2011)
Inducing local T cell apoptosis with anti-Fas-functionalized polymeric coatings fabricated via surface-initiated photopolymerizations
Patrick S. Hume et al.
BIOMATERIALS (2010)
Astrocytes initiate inflammation in the injured mouse spinal cord by promoting the entry of neutrophils and inflammatory monocytes in an IL-1 receptor/MyD88-dependent fashion
Isabelle Pineau et al.
BRAIN BEHAVIOR AND IMMUNITY (2010)
Anti-IL-6-receptor antibody promotes repair of spinal cord injury by inducing microglia-dominant inflammation
Masahiko Mukaino et al.
EXPERIMENTAL NEUROLOGY (2010)
The topographical effect of electrospun nanofibrous scaffolds on the in vivo and in vitro foreign body reaction
Haoqing Cao et al.
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A (2010)
Adult NG2+Cells Are Permissive to Neurite Outgrowth and Stabilize Sensory Axons during Macrophage-Induced Axonal Dieback after Spinal Cord Injury
Sarah A. Busch et al.
JOURNAL OF NEUROSCIENCE (2010)
Endogenous Expression of Interleukin-4 Regulates Macrophage Activation and Confines Cavity Formation After Traumatic Spinal Cord Injury
Seung Ihm Lee et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2010)
Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages
Florent Ginhoux et al.
SCIENCE (2010)
B cells and autoantibodies: complex roles in CNS injury
Daniel P. Ankeny et al.
TRENDS IN IMMUNOLOGY (2010)
Macrophage phenotype and remodeling outcomes in response to biologic scaffolds with and without a cellular component
Bryan N. Brown et al.
BIOMATERIALS (2009)
Microglia Processes Block the Spread of Damage in the Brain and Require Functional Chloride Channels
Dustin J. Hines et al.
GLIA (2009)
Impact of polymer hydrophilicity on biocompatibility: Implication for DES polymer design
Ayala Hezi-Yamit et al.
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A (2009)
B cells produce pathogenic antibodies and impair recovery after spinal cord injury in mice
Daniel P. Ankeny et al.
JOURNAL OF CLINICAL INVESTIGATION (2009)
PAL31 may play an important role as inflammatory modulator in the repair process of the spinal cord injury rat
Li-Fen Shen et al.
JOURNAL OF NEUROCHEMISTRY (2009)
Absence of endogenous interleukin-10 enhances secondary inflammatory process after spinal cord compression injury in mice
Tiziana Genovese et al.
JOURNAL OF NEUROCHEMISTRY (2009)
Depletion of Ly6G/Gr-1 Leukocytes after Spinal Cord Injury in Mice Alters Wound Healing and Worsens Neurological Outcome
David P. Stirling et al.
JOURNAL OF NEUROSCIENCE (2009)
The bioenergetic and antioxidant status of neurons is controlled by continuous degradation of a key glycolytic enzyme by APC/C-Cdh1
Angel Herrero-Mendez et al.
NATURE CELL BIOLOGY (2009)
Pathological and protective roles of glia in chronic pain
Erin D. Milligan et al.
NATURE REVIEWS NEUROSCIENCE (2009)
Neuroprotective effects of infliximab in experimental spinal cord injury
Goekhan Kurt et al.
SURGICAL NEUROLOGY (2009)
Spatial distribution and acute anti-inflammatory effects of Methylprednisolone after sustained local delivery to the contused spinal cord
Stacie A. Chvatal et al.
BIOMATERIALS (2008)
Characterization of microglial attachment and cytokine release on biomaterials of differing surface chemistry
Braden K. Leung et al.
BIOMATERIALS (2008)
MicroRNA miR-124 regulates neurite outgrowth during neuronal differentiation
Jenn-Yah Yu et al.
EXPERIMENTAL CELL RESEARCH (2008)
Inflammation and its role in neuroprotection, axonal regeneration and functional recovery after spinal cord injury
Dustin J. Donnelly et al.
EXPERIMENTAL NEUROLOGY (2008)
Dynamics of the inflammatory response after murine spinal cord injury revealed by flow cytometry
David P. Stirling et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2008)
Distinct roles of matrix metalloproteases in the early- and late-phase development of neuropathic pain
Yasuhiko Kawasaki et al.
NATURE MEDICINE (2008)
Analysis of FK506-mediated protection in an organotypic model of spinal cord damage: Heat shock protein 70 levels are modulated in microglial cells
M. -S. Guzman-Lenis et al.
NEUROSCIENCE (2008)
Current status of acute spinal cord injury pathophysiology and emerging therapies: promise on the horizon
James W. Rowland et al.
NEUROSURGICAL FOCUS (2008)
Foreign body reaction to biomaterials
James M. Anderson et al.
SEMINARS IN IMMUNOLOGY (2008)
Proteomic analysis and quantification of cytokines and chemokines from biomaterial surface-adherent macrophages and foreign body giant cells
Jacqueline A. Jones et al.
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A (2007)
Spinal cord injury: Time to move?
Serge Rossignol et al.
JOURNAL OF NEUROSCIENCE (2007)
Therapeutic neutralization of CXCL 10 decreases secondary degeneration and functional deficit after spinal cord injury in mice
Rafael Gonzalez et al.
REGENERATIVE MEDICINE (2007)
Glial-cytokine-neuronal interactions underlying the mechanisms of persistent pain
Wei Guo et al.
JOURNAL OF NEUROSCIENCE (2007)
Neutrophils and the blood-brain barrier dysfunction after trauma
Martin Scholz et al.
MEDICINAL RESEARCH REVIEWS (2007)
The microRNA miR-124 antagonizes the anti-neural REST/SCP1 pathway during embryonic CNS development
Jaya Visvanathan et al.
GENES & DEVELOPMENT (2007)
Cytokines, Inflammation, and Pain
Jun-Ming Zhang et al.
INTERNATIONAL ANESTHESIOLOGY CLINICS (2007)
Subacute human spinal cord contusion: few lymphocytes and many macrophages
H. T. Chang
SPINAL CORD (2007)
Axon regeneration through scars and into sites of chronic spinal cord injury
Paul Lu et al.
EXPERIMENTAL NEUROLOGY (2007)
Altered pain behavior and regeneration after nerve injury in TNF receptor deficient mice
Carola Vogel et al.
JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM (2006)
The cellular inflammatory response in human spinal cords after injury
Jennifer C. Fleming et al.
BRAIN (2006)
A therapeutic time window for anti-CD11d monoclonal antibody treatment yielding reduced secondary tissue damage and enhanced behavioral recovery following severe spinal cord injury
David S. Ditor et al.
JOURNAL OF NEUROSURGERY-SPINE (2006)
Conditional ablation of Stat3 or Socs3 discloses a dual role for reactive astrocytes after spinal cord injury
Seiji Okada et al.
NATURE MEDICINE (2006)
NG2 glial cells provide a favorable substrate for growing axons
ZS Yang et al.
JOURNAL OF NEUROSCIENCE (2006)
Neutrophils and immunity: challenges and opportunities
C Nathan
NATURE REVIEWS IMMUNOLOGY (2006)
Myelin impairs CNS remyelination by inhibiting oligodendrocyte precursor cell differentiation
MR Kotter et al.
JOURNAL OF NEUROSCIENCE (2006)
Immunosuppression with either cyclosporine A or FK506 supports survival of transplanted fibroblasts and promotes growth of host axons into the transplant after spinal cord injury
Y Hayashi et al.
JOURNAL OF NEUROTRAUMA (2005)
FK506 reduces tissue damage and prevents functional deficit after spinal cord injury in the rat
R López-Vales et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2005)
Interleukin-1 beta induction of neuron apoptosis depends on p38 mitogen-activated protein kinase activity after spinal cord injury
XJ Wang et al.
ACTA PHARMACOLOGICA SINICA (2005)
Inhibition of astroglial nuclear factor κB reduces inflammation and improves functional recovery after spinal cord injury
R Brambilla et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2005)
Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo
A Nimmerjahn et al.
SCIENCE (2005)
Protective autoimmunity:: interferon-γ enables microglia to remove glutamate without evoking inflammatory mediators
I Shaked et al.
JOURNAL OF NEUROCHEMISTRY (2005)
Inflammation-induced GDNF improves locomotor function after spinal cord injury
M Hashimoto et al.
NEUROREPORT (2005)
Secreted proNGF is a pathophysiological death-inducing ligand after adult CNS injury
AW Harrington et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Blockade of interleukin-6 receptor suppresses reactive astrogliosis and ameliorates functional recovery in experimental spinal cord injury
S Okada et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2004)
The pathology of human spinal cord injury: Defining the problems
MD Norenberg et al.
JOURNAL OF NEUROTRAUMA (2004)
Sortilin is essential for proNGF-induced neuronal cell death
A Nykjaer et al.
NATURE (2004)
Long-term changes in the molecular composition of the glial scar and progressive increase of serotoninergic fibre sprouting after hemisection of the mouse spinal cord
E Camand et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2004)
Fibrotic disease and the TH1/TH2 paradigm
TA Wynn
NATURE REVIEWS IMMUNOLOGY (2004)
A monoclonal antibody to CD11d reduces the inflammatory infiltrate into the injured spinal cord: a potential neuroprotective treatment
LR Saville et al.
JOURNAL OF NEUROIMMUNOLOGY (2004)
The role of excitotoxicity in secondary mechanisms of spinal cord injury: A review with an emphasis on the implications for white matter degeneration
E Park et al.
JOURNAL OF NEUROTRAUMA (2004)
Effect of intravenous corticosteroids on death within 14 days in 10008 adults with clinically significant head injury (MRC CRASH trial):: randomised placebo-controlled trial
I Muzha et al.
LANCET (2004)
Early expression and cellular localization of proinflammatory cytokines interleukin-1β, interleukin-6, and tumor necrosis factor-α in human traumatic spinal cord injury
LQ Yang et al.
SPINE (2004)
Rats and mice exhibit distinct inflammatory reactions after spinal cord injury
JM Sroga et al.
JOURNAL OF COMPARATIVE NEUROLOGY (2003)
Neutrophil survival on biomaterials is determined by surface topography
S Chang et al.
JOURNAL OF VASCULAR SURGERY (2003)
Neuroprotective autoimmunity:: Naturally occurring CD4+CD25+ regulatory T cells suppress the ability to withstand injury to the central nervous system
J Kipnis et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
ProNGF induces p75-mediated death of oligodendrocytes following spinal cord injury
MS Beattie et al.
NEURON (2002)
Acute modulation of synaptic transmission to motoneurons by BDNF in the neonatal rat spinal cord
VL Arvanian et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2001)
Apoptosis of inflammatory cells in immune control of the nervous system: Role of glia
MP Pender et al.
GLIA (2001)
Vitamin E suppression of microglial activation is neuroprotective
YK Li et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2001)
Chemokine antagonist infusion promotes axonal sparing after spinal cord contusion injury in rat
RS Ghirnikar et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2001)
Protective autoimmunity: regulation and prospects for vaccination after brain and spinal cord injuries
M Schwartz et al.
TRENDS IN MOLECULAR MEDICINE (2001)
The molecular basis of T helper 1 and T helper 2 cell differentiation
A O'Garra et al.
TRENDS IN CELL BIOLOGY (2000)
Inhibition of monocyte/macrophage migration to a spinal cord injury site by an antibody to the integrin αD:: A potential new anti-inflammatory treatment
PJ Mabon et al.
EXPERIMENTAL NEUROLOGY (2000)
Neuroprotection by encephalomyelitis:: Rescue of mechanically injured neurons and neurotrophin production by CNS-infiltrating T and natural killer cells
H Hammarberg et al.
JOURNAL OF NEUROSCIENCE (2000)
Extensive sprouting of sensory afferents and hyperalgesia induced by conditional expression of nerve growth factor in the adult spinal cord
MI Romero et al.
JOURNAL OF NEUROSCIENCE (2000)