Related references
Note: Only part of the references are listed.DHX9 contributes to the malignant phenotypes of colorectal cancer via activating NF-κB signaling pathway
Shenglan Liu et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2021)
DCBLD2 Affects the Development of Colorectal Cancer via EMT and Angiogenesis and Modulates 5-FU Drug Resistance
Pan Xie et al.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2021)
CCDC137 Is a Prognostic Biomarker and Correlates With Immunosuppressive Tumor Microenvironment Based on Pan-Cancer Analysis
Lihao Guo et al.
FRONTIERS IN MOLECULAR BIOSCIENCES (2021)
BCL-XL is crucial for progression through the adenoma-to-carcinoma sequence of colorectal cancer
Prashanthi Ramesh et al.
CELL DEATH AND DIFFERENTIATION (2021)
Super-enhancer landscape reveals leukemia stem cell reliance on X-box binding protein 1 as a therapeutic vulnerability
Jingfeng Zhou et al.
SCIENCE TRANSLATIONAL MEDICINE (2021)
Oncogenic enhancers drive esophageal squamous cell carcinogenesis and metastasis
Bo Ye et al.
NATURE COMMUNICATIONS (2021)
Degradation of CCNK/CDK12 is a druggable vulnerability of colorectal cancer
Sebastian M. Dieter et al.
CELL REPORTS (2021)
Activation of transmembrane receptor tyrosine kinase DDR1-STAT3 cascade by extracellular matrix remodeling promotes liver metastatic colonization in uveal melanoma
Wei Dai et al.
SIGNAL TRANSDUCTION AND TARGETED THERAPY (2021)
CDK12 inhibition mediates DNA damage and is synergistic with sorafenib treatment in hepatocellular carcinoma
Cun Wang et al.
GUT (2020)
Epigenetic Profiling Identifies LIF as a Super-enhancer-Controlled Regulator of Stem Cell-like Properties in Osteosarcoma
Bing Lu et al.
MOLECULAR CANCER RESEARCH (2020)
Targeting Super-Enhancer-Associated Oncogenes in Osteosarcoma with THZ2, a Covalent CDK7 Inhibitor
Jiajun Zhang et al.
CLINICAL CANCER RESEARCH (2020)
DNA of neutrophil extracellular traps promotes cancer metastasis via CCDC25
Linbin Yang et al.
NATURE (2020)
CDK12/13 inhibition induces immunogenic cell death and enhances anti-PD-1 anticancer activity in breast cancer
Yi Li et al.
CANCER LETTERS (2020)
Neurotensin pathway in digestive cancers and clinical applications: an overview
Niki Christou et al.
CELL DEATH & DISEASE (2020)
A prognostic stemness biomarker CCDC80 reveals acquired drug resistance and immune infiltration in colorectal cancer
Wei-Da Wang et al.
CLINICAL AND TRANSLATIONAL MEDICINE (2020)
Aberrant Super-Enhancer Landscape in Human Hepatocellular Carcinoma
Felice Ho-Ching Tsang et al.
HEPATOLOGY (2019)
PD-L1 promotes colorectal cancer stem cell expansion by activating HMGA1-dependent signaling pathways
Fang Wei et al.
CANCER LETTERS (2019)
CDK12 loss in cancer cells affects DNA damage response genes through premature cleavage and polyadenylation
Malgorzata Krajewska et al.
NATURE COMMUNICATIONS (2019)
Ex vivo screen identifies CDK12 as a metastatic vulnerability in osteosarcoma
Ian Bayles et al.
JOURNAL OF CLINICAL INVESTIGATION (2019)
SEdb: a comprehensive human super-enhancer database
Yong Jiang et al.
NUCLEIC ACIDS RESEARCH (2019)
Transcription regulation by the Mediator complex
Julie Soutourina
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2018)
dbCoRC: a database of core transcriptional regulatory circuitries modeled by H3K27ac ChIP-seq signals
Moli Huang et al.
NUCLEIC ACIDS RESEARCH (2018)
BET Proteins as Targets for Anticancer Treatment
Anastasios Stathis et al.
CANCER DISCOVERY (2018)
EWS/FLI Confers Tumor Cell Synthetic Lethality to CDK12 Inhibition in Ewing Sarcoma
Amanda Balboni Iniguez et al.
CANCER CELL (2018)
High MITF Expression Is Associated with Super-Enhancers and Suppressed by CDK7 Inhibition in Melanoma
Philip Eliades et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2018)
Neddylation Blockade Diminishes Hepatic Metastasis by Dampening Cancer Stem-Like Cells and Angiogenesis in Uveal Melanoma
Yanli Jin et al.
CLINICAL CANCER RESEARCH (2018)
Targeting super-enhancer-associated oncogenes in oesophageal squamous cell carcinoma
Yan-Yi Jiang et al.
GUT (2017)
Prediction of novel target genes and pathways involved in irinotecan-resistant colorectal cancer
Precious Takondwa Makondi et al.
PLOS ONE (2017)
Enhancer Reprogramming Promotes Pancreatic Cancer Metastasis
Jae-Seok Roe et al.
CELL (2017)
BET Inhibitors Suppress ALDH Activity by Targeting ALDH1A1 Super-Enhancer in Ovarian Cancer
Yuhki Yokoyama et al.
CANCER RESEARCH (2016)
Metastatic colonization by circulating tumour cells
Joan Massague et al.
NATURE (2016)
Covalent targeting of remote cysteine residues to develop CDK12 and CDK13 inhibitors
Tinghu Zhang et al.
NATURE CHEMICAL BIOLOGY (2016)
Loss of zfp36 expression in colorectal cancer correlates to wnt/β-catenin activity and enhances epithelial-to-mesenchymal transition through upregulation of zeb1, sox9 and macc1
Lucia Montorsi et al.
ONCOTARGET (2016)
Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex
Silvana Konermann et al.
NATURE (2015)
What are super-enhancers?
Sebastian Pott et al.
NATURE GENETICS (2015)
Highly specific epigenome editing by CRISPR-Cas9 repressors for silencing of distal regulatory elements
Pratiksha I. Thakore et al.
NATURE METHODS (2015)
Targeting Transcriptional Addictions in Small Cell Lung Cancer with a Covalent CDK7 Inhibitor
Camilla L. Christensen et al.
CANCER CELL (2014)
CDK7 Inhibition Suppresses Super-Enhancer-Linked Oncogenic Transcription in MYCN-Driven Cancer
Edmond Chipumuro et al.
CELL (2014)
A Systems Biology Approach for Defining the Molecular Framework of the Hematopoietic Stem Cell Niche
Pierre Charbord et al.
CELL STEM CELL (2014)
SMAD2, SMAD3 and SMAD4 Mutations in Colorectal Cancer
Nicholas I. Fleming et al.
CANCER RESEARCH (2013)
Tumor Metastasis: Molecular Insights and Evolving Paradigms
Scott Valastyan et al.
CELL (2011)
A Perspective on Cancer Cell Metastasis
Christine L. Chaffer et al.
SCIENCE (2011)
WNT/TCF Signaling through LEF1 and HOXB9 Mediates Lung Adenocarcinoma Metastasis
Don X. Nguyen et al.
CELL (2009)
Share Paper
