4.7 Article

Lack of evidence of viability and infectivity of SARS-CoV-2 in the fecal specimens of COVID-19 patients

Related references

Note: Only part of the references are listed.
Article Virology

Isolation and Genomic Characterization of SARS-CoV-2 Omicron Variant Obtained from Human Clinical Specimens

Pragya D. Yadav et al.

Summary: Due to the failure of virus isolation in Vero CCL-81 cells, an in vivo and subsequent in vitro approach were used to isolate the Omicron variant. The virus was successfully isolated from hamster specimens and showed high viral load and cytopathic effects in infected cells. Genome analysis revealed mutations in different host species.

VIRUSES-BASEL (2022)

Article Medicine, General & Internal

Prolonged Shedding of SARS-CoV-2 in Feces of COVID-19 Positive Patients: Trends in Genomic Variation in First and Second Wave

Mallika Lavania et al.

Summary: The main routes of transmission for SARS-CoV-2 are through respiratory pathways and close contact. While the possibility of fecal-oral transmission has been supported by some published literature, it is not yet clear how fecal viral load is related to disease severity. This study investigated SARS-CoV-2 shedding in fecal samples of COVID-19 patients and found that about 62% of patients tested positive for SARS-CoV-2 RNA in their fecal specimens. However, this positivity was not related to gastrointestinal symptoms or disease severity.

FRONTIERS IN MEDICINE (2022)

Article Infectious Diseases

Lack of evidence for infectious SARS-CoV-2 in feces and sewage

Sandra Albert et al.

Summary: The study found no evidence of infective viral particles in feces and wastewater samples of COVID-19 patients, indicating that fecal-oral transmission is not a primary route. However, further large-scale research is needed with the emergence of new viral variants.

EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES (2021)

Article Public, Environmental & Occupational Health

Detection of SARS-CoV-2 RNA on contact surfaces within shared sanitation facilities

Isaac Dennis Amoah et al.

Summary: Contamination of shared toilet contact surfaces with SARS-CoV-2 poses a potential route for COVID-19 transmission. Toilet seats had the highest viral load, likely due to fecal and urine shedding. Effective cleaning of these surfaces can reduce contamination and infection risks.

INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH (2021)

Letter Immunology

Transmission of COVID-19 infection within a family cluster in Pune, India

Sujata Ranshing et al.

INDIAN JOURNAL OF MEDICAL RESEARCH (2021)

Article Medicine, General & Internal

Serial Screening for SARS-CoV-2 in Rectal Swabs of Symptomatic COVID-19 Patients

Sung Hoon Jung et al.

Summary: Rectal swabs were found to have lower viral loads compared to respiratory specimens, and were negative after respiratory specimens turned negative. This suggests that rectal swabs may play a role in detecting SARS-CoV-2 in individuals suspected of having COVID-19, regardless of gastrointestinal symptoms.

JOURNAL OF KOREAN MEDICAL SCIENCE (2021)

Article Immunology

Phylogenetic classification of the whole-genome sequences of SARS-CoV-2 from India & evolutionary trends

Varsha Potdar et al.

Summary: This study integrated existing classifications to describe evolution trends of SARS-CoV-2 strains in India through phylogenetic and sequence analysis of 330 samples. It identified new lineages B.1.1.8 and B.1.113 as indigenous evolutions and hotspot mutations under positive selection pressure in non-structural proteins. Further characterization of these mutations is necessary for a comprehensive understanding.

INDIAN JOURNAL OF MEDICAL RESEARCH (2021)

Review Infectious Diseases

SARS-CoV-2, SARS-CoV, and MERS-CoV viral load dynamics, duration of viral shedding, and infectiousness: a systematic review and meta-analysis

Muge Cevik et al.

Summary: This study aimed to characterize the viral load dynamics, duration of viral shedding, and viable virus shedding of SARS-CoV-2 in various body fluids. The findings suggest that while SARS-CoV-2 RNA shedding can be prolonged in respiratory and stool samples, the duration of viable virus shedding is relatively short-lived.

LANCET MICROBE (2021)

Article Medicine, General & Internal

Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China

Dawei Wang et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2020)

Article Virology

The presence of SARS-CoV-2 RNA in the feces of COVID-19 patients

Yifei Chen et al.

JOURNAL OF MEDICAL VIROLOGY (2020)

Article Multidisciplinary Sciences

Pathogenesis and transmission of SARS-CoV-2 in golden hamsters

Sin Fun Sia et al.

NATURE (2020)

Article Multidisciplinary Sciences

Virological assessment of hospitalized patients with COVID-2019

Roman Woelfel et al.

NATURE (2020)

Letter Gastroenterology & Hepatology

Prolonged presence of SARS-CoV-2 viral RNA in faecal samples

Yongjian Wu et al.

LANCET GASTROENTEROLOGY & HEPATOLOGY (2020)

Editorial Material Public, Environmental & Occupational Health

Incident SARS-CoV-2 Infection and a Shared Latrine

Oscar H. Del Brutto et al.

AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE (2020)

Article Multidisciplinary Sciences

SARS-CoV-2 is transmitted via contact and via the air between ferrets

Mathilde Richard et al.

NATURE COMMUNICATIONS (2020)

Letter Immunology

Transmission electron microscopy imaging of SARS-CoV-2

Sharda Prasad et al.

INDIAN JOURNAL OF MEDICAL RESEARCH (2020)

Letter Immunology

First isolation of SARS-CoV-2 from clinical samples in India

Prasad Sarkale et al.

INDIAN JOURNAL OF MEDICAL RESEARCH (2020)

Letter Immunology

Development of in vitro transcribed RNA as positive control for laboratory diagnosis of SARS-CoV-2 in India

Manohar Lal Choudhary et al.

INDIAN JOURNAL OF MEDICAL RESEARCH (2020)

Article Virology

Real-time RT-PCR detection of 12 respiratory viral infections in four triplex reactions

RN Gunson et al.

JOURNAL OF CLINICAL VIROLOGY (2005)

Article Immunology

Laboratory diagnosis of SARS

PKS Chan et al.

EMERGING INFECTIOUS DISEASES (2004)