COVID-19 vaccine hesitancy and GAD: The role of risk perception and vaccination status

Background and purposeAs Coronavirus disease (COVID-19) continues to spread around the world, COVID-19 vaccines are the most effective weapons against the global pandemic. Yet vaccine hesitancy remains a serious problem and can pose certain hazards to individuals' mental health, such as rising anxiety. Therefore, based on Self-Discrepancy Theory, this paper aims to explore the role of COVID-19 vaccine hesitancy on individual generalized anxiety disorder and its influence mechanisms through two studies. MethodsStudy one involved 654 Chinese participants using the Vaccine Hesitancy Questionnaire and the Generalized Anxiety Disorder 7-item (GAD-7) scale. In Study two, the Vaccine Hesitation Questionnaire, GAD-7 scale, Perceived Risk of COVID-19 pandemic scale, and Vaccination Status Questionnaire were used and data from 3,282 Chinese residents was collected. ResultsVaccine hesitancy directly increases generalized anxiety disorder; risk perception plays a partial mediating role between vaccine hesitancy and generalized anxiety disorder; vaccination status moderated vaccine hesitancy's effect on risk perception and generalized anxiety disorder. ConclusionVaccine hesitancy predicts generalized anxiety disorder through risk perception, but the mediating role of risk perception is moderated by vaccination status, which means that for the vaccinated group when their vaccine hesitancy is reduced, it will be easier to reduce the risk perception and thus the generalized anxiety disorder.

Automated summary

This paper investigates the impact and mechanisms of COVID-19 vaccine hesitancy on generalized anxiety disorder. The results indicate that vaccine hesitancy directly contributes to generalized anxiety disorder, and risk perception partially mediates the relationship between the two. Furthermore, the effect of vaccine hesitancy on risk perception and generalized anxiety disorder is moderated by vaccination status.