4.7 Article

Pharmacokinetics and Tissue Distribution of Coumarins from Tagetes lucida in an LPS-Induced Neuroinflammation Model

Related references

Note: Only part of the references are listed.
Article Plant Sciences

Medicinal plants used in traditional Mayan medicine for the treatment of central nervous system disorders: An overview

Rodrigo Castaneda et al.

Summary: The study provides an overview of medicinal plants used by traditional healers and Mayan groups in Mesoamerica for CNS disorders, linking traditional use with pharmacological evidence. The research found 155 plants used for ethnopsychiatric conditions, with only 49 native species having reported pharmacological analyses. The study emphasizes the need for further research due to limited data on mechanism of action and lack of clinical studies.

JOURNAL OF ETHNOPHARMACOLOGY (2022)

Article Chemistry, Applied

Isolation, chemical characterization, and anti-inflammatory activity of coumarins, flavonoids, and terpenes from Tagetes lucida

Porras-Davila Sandra Liliana et al.

Summary: In this study, fifteen compounds were identified from Tagetes lucida, with some being detected for the first time in the plant. These compounds exhibited varying degrees of inflammation inhibition effects, with compounds 12 and 13 showing a dose-response behavior.

NATURAL PRODUCT RESEARCH (2022)

Article Multidisciplinary Sciences

Neuropsychopharmacological profiling of scoparone in mice

Joanna Kowalczyk et al.

Summary: Scoparone, a compound found in traditional Chinese medicine and Genepi liquor, has been found to have potent central effects in mice, which may have toxicopharmacological implications for humans.

SCIENTIFIC REPORTS (2022)

Article Plant Sciences

Antihypertensive and vasorelaxant mode of action of the ethanol-soluble extract from Tagetes lucida Cav. aerial parts and its main bioactive metabolites

Samuel Estrada-Soto et al.

Summary: The study on the extract of Tagetes lucida Cav. confirms its antihypertensive properties, mainly achieved through vasorelaxant effect by activating the NO/cGMP system and calcium channel blockade. Additionally, active compounds like 6,7,8-trimethoxycoumarin also significantly contribute to vasorelaxation.

JOURNAL OF ETHNOPHARMACOLOGY (2021)

Article Chemistry, Applied

Anti-inflammatory activity of coumarins isolated from Tagetes lucida Cav.

Monterrosas-Brisson Nayeli et al.

NATURAL PRODUCT RESEARCH (2020)

Review Biochemistry & Molecular Biology

Lipopolysaccharide-Induced Neuroinflammation as a Bridge to Understand Neurodegeneration

Carla Ribeiro Alvares Batista et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)

Article Medicine, Research & Experimental

Identification of some bioactive metabolites and inhibitory receptors in the antinociceptive activity of Tagetes lucida Cav.

Maria Eva Gonzalez-Trujano et al.

LIFE SCIENCES (2019)

Review Medicine, Research & Experimental

Toxicology and Biodistribution: The Clinical Value of Animal Biodistribution Studies

Beatriz Silva Lima et al.

MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT (2018)

Review Biochemistry & Molecular Biology

Tagetes spp. Essential Oils and Other Extracts: Chemical Characterization and Biological Activity

Bahare Salehi et al.

MOLECULES (2018)

Article Plant Sciences

Tagetes lucida Cav.: Ethnobotany, phytochemistry and pharmacology of its tranquilizing properties

G. Perez-Ortega et al.

JOURNAL OF ETHNOPHARMACOLOGY (2016)

Article Biochemistry & Molecular Biology

Neuroinflammation: the devil is in the details

Damon J. DiSabato et al.

JOURNAL OF NEUROCHEMISTRY (2016)

Article Chemistry, Medicinal

Antidepressant-like activity of Tagetes lucida Cav. is mediated by 5-HT1A and 5-HT2A receptors

H. Bonilla-Jaime et al.

JOURNAL OF NATURAL MEDICINES (2015)

Review Neurosciences

Neuroinflammation: The role and consequences

Monty Lyman et al.

NEUROSCIENCE RESEARCH (2014)

Article Computer Science, Interdisciplinary Applications

PKSolver: An add-in program for pharmacokinetic and pharmacodynamic data analysis in Microsoft Excel

Yong Zhang et al.

COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE (2010)

Article Pharmacology & Pharmacy

Impact of Infectious and Inflammatory Disease on Cytochrome P450-Mediated Drug Metabolism and Pharmacokinetics

E. T. Morgan

CLINICAL PHARMACOLOGY & THERAPEUTICS (2009)

Article Agriculture, Multidisciplinary

Antifungal and antibacterial activities of Mexican tarragon (Tagetes lucida)

Carlos L. Cespedes et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2006)