4.6 Article

Prediction of Potential Natural Antibiotics Plants Based on Jamu Formula Using Random Forest Classifier

Journal

ANTIBIOTICS-BASEL
Volume 11, Issue 9, Pages -

Publisher

MDPI
DOI: 10.3390/antibiotics11091199

Keywords

herbal plants; Jamu; natural antibiotics; prediction; Random Forest

Funding

  1. Ministry of Education, Culture, Sports, Science, and Technology of Japan [20K12043]
  2. NAIST Big Data Project
  3. National Bioscience Database Center in Japan

Ask authors/readers for more resources

Jamu is a traditional Indonesian herbal medicine system that is considered to have many benefits. This study uses a machine learning approach to discover the potential of 14 plants as natural antibiotic candidates.
Jamu is the traditional Indonesian herbal medicine system that is considered to have many benefits such as serving as a cure for diseases or maintaining sound health. A Jamu medicine is generally made from a mixture of several herbs. Natural antibiotics can provide a way to handle the problem of antibiotic resistance. This research aims to discover the potential of herbal plants as natural antibiotic candidates based on a machine learning approach. Our input data consists of a list of herbal formulas with plants as their constituents. The target class corresponds to bacterial diseases that can be cured by herbal formulas. The best model has been observed by implementing the Random Forest (RF) algorithm. For 10-fold cross-validations, the maximum accuracy, recall, and precision are 91.10%, 91.10%, and 90.54% with standard deviations 1.05, 1.05, and 1.48, respectively, which imply that the model obtained is good and robust. This study has shown that 14 plants can be potentially used as natural antibiotic candidates. Furthermore, according to scientific journals, 10 of the 14 selected plants have direct or indirect antibacterial activity.

Authors

I am an author on this paper
Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.6
Not enough ratings

Secondary Ratings

Novelty
-
Significance
-
Scientific rigor
-
Rate this paper

Recommended

No Data Available
No Data Available