4.7 Article

NMR-Based Metabolomics to Decipher the Molecular Mechanisms in the Action of Gut-Modulating Foods

Journal

FOODS
Volume 11, Issue 17, Pages -

Publisher

MDPI
DOI: 10.3390/foods11172707

Keywords

gut-host associations; saccharolytic activity; unfavorable metabolites; calcium

Funding

  1. Danish Dairy Research Foundation
  2. Innovation Fund Denmark [9090-00017B]
  3. China Scholarship Council

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This review discusses the importance of using nuclear magnetic resonance (NMR)-based metabolomics in food and nutrition science to gain a better understanding of the impact of food and food components on gut health.
Metabolomics deals with uncovering and characterizing metabolites present in a biological system, and is a leading omics discipline as it provides the nearest link to the biological phenotype. Within food and nutrition, metabolomics applied to fecal samples and bio-fluids has become an important tool to obtain insight into how food and food components may exert gut-modulating effects. This review aims to highlight how nuclear magnetic resonance (NMR)-based metabolomics in food and nutrition science may help us get beyond where we are today in understanding foods' inherent, or added, biofunctionalities in relation to gut health.

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