4.6 Review

Anti-colorectal cancer effects of seaweed-derived bioactive compounds

Journal

FRONTIERS IN MEDICINE
Volume 9, Issue -, Pages -

Publisher

FRONTIERS MEDIA SA
DOI: 10.3389/fmed.2022.988507

Keywords

colorectal cancer; therapeutic compounds; Chlorophyta; Rhodophyta; Phaeophyta

Funding

  1. Scientific and Technological Development Program of Jilin Province of China
  2. [20210401065YY]
  3. [20210204046YY]

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Seaweeds, classified into different categories, contain bioactive compounds with anticancer properties. This review focuses on the potential utility of seaweeds as anticancer agents, particularly in the context of colorectal cancer. The mechanisms through which seaweed-derived compounds induce apoptosis in colorectal cancer cells are explored.
Seaweeds are classified as Chlorophyta, Rhodophyta, and Phaeophyta. They constitute a number of the most significant repositories of new therapeutic compounds for human use. Seaweed has been proven to possess diverse bioactive properties, which include anticancer properties. The present review focuses on colorectal cancer, which is a primary cause of cancer-related mortality in humans. In addition, it discusses various compounds derived from a series of seaweeds that have been shown to eradicate or slow the progression of cancer. Therapeutic compounds extracted from seaweed have shown activity against colorectal cancer. Furthermore, the mechanisms through which these compounds can induce apoptosis in vitro and in vivo were reviewed. This review emphasizes the potential utility of seaweeds as anticancer agents through the consideration of the capability of compounds present in seaweeds to fight against colorectal cancer.

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