Outcomes of Patients Receiving a Kidney Transplant or Remaining on the Transplant Waiting List at the Epicentre of the COVID-19 Pandemic in Europe: An Observational Comparative Study

Article Immunology

Global Impact of the COVID-19 Pandemic on Solid Organ Transplant

Vivek B. Kute et al.

Summary: COVID-19 has had a disproportionate impact on transplantation services across different regions of the world, with developed nations recovering more easily during the pandemic compared to developing countries.

TRANSPLANTATION PROCEEDINGS (2022)

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Review Hematology

The Impact of the SARS-CoV-2 Pandemic on Healthcare Provision in Italy to non-COVID Patients: a Systematic Review

Gianmarco Lugli et al.

Summary: The study revealed a decrease in emergency management for non-COVID patients, an increase in mortality, and a decrease in diagnosis for non-deferrable conditions in Italy during the COVID-19 pandemic. All medical specialties were impacted by healthcare reorganization and benefited from telemedicine.

MEDITERRANEAN JOURNAL OF HEMATOLOGY AND INFECTIOUS DISEASES (2022)

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Article Medicine, General & Internal

The Kidney Donor Profile Index (KDPI) Correlates With Histopathologic Findings in Post-reperfusion Baseline Biopsies and Predicts Kidney Transplant Outcome

Quirin Bachmann et al.

Summary: The increasing organ shortage in kidney transplantation leads to the necessity to use kidneys previously considered unsuitable for transplantation. There is a need for better decision guidance and more accurate tools to assess organ quality.

FRONTIERS IN MEDICINE (2022)

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Review Virology

Transplantation in the era of the Covid-19 pandemic: How should transplant patients and programs be handled?

Mohamed M. NasrAllah et al.

Summary: The Covid-19 pandemic has significantly impacted transplant programs globally, with varying outcomes in SARS-CoV-2 infection among transplant recipients. Further research is needed to determine optimal management strategies and potential adjustments to immunosuppressive medications for this population.

REVIEWS IN MEDICAL VIROLOGY (2021)

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Article Surgery

The impact of the SARS-CoV-2 pandemic and COVID-19 on lung transplantation in the UK: Lessons learned from the first wave

Gillian Hardman et al.

Summary: This study conducted in the UK found significant impact of the COVID-19 pandemic on lung transplantation, with decreased number of donors, reduced transplant surgeries, and increased number of patients on the waiting list. The study highlights the importance of reviewing practice and implementing lessons learned during the pandemic to ensure the safe continuation of lung transplant programs.

CLINICAL TRANSPLANTATION (2021)

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Review Biochemistry & Molecular Biology

COVID-19: A Global Challenge with Old History, Epidemiology and Progress So Far

Mujeeb Khan et al.

Summary: The article summarizes the three deadly pandemics associated with novel coronaviruses that humans have witnessed in the twenty-first century: SARS, MERS, and COVID-19. Specifically, it describes the epidemiological characteristics of COVID-19, such as transmission, death rate, and discusses various treatment strategies and different approaches to vaccine development.

MOLECULES (2021)

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Review Immunology

Solid Organ Transplantation in the Era of COVID-19: Lessons from France

Mohamad Zaidan et al.

Summary: The COVID-19 outbreak has disrupted solid organ transplant practices globally, with high infection rates in recipients and challenging treatment strategies. Controlled studies are helping to improve patient outcomes, but evidence-based recommendations for transplant recipients remain unclear.

TRANSPLANTATION (2021)

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Review Surgery

The impact of COVID-19 on kidney transplantation and the kidney transplant recipient - One year into the pandemic

Pascale Khairallah et al.

Summary: The COVID-19 pandemic has significantly impacted kidney transplantation, affecting patient and allograft survival, transplant referrals, organ donation rates, and clinical management decisions. Transplant centers and physicians have made critical decisions considering patient safety and resource utilization. New considerations have arisen with the administration of COVID vaccines.

TRANSPLANT INTERNATIONAL (2021)

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Article Surgery

A Closer Look Into Global Hospital Beds Capacity and Resource Shortages During the COVID-19 Pandemic

Brendon Sen-Crowe et al.

Summary: The global COVID-19 mortality rates may be influenced by factors such as hospital resources, personnel, and bed capacity, with higher income regions having greater ICU, acute care, and hospital bed capacities. There is a weak but significant positive correlation between the number of ICU beds and COVID-19 mortality.

JOURNAL OF SURGICAL RESEARCH (2021)

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Article Public, Environmental & Occupational Health

Salus Populi Suprema Lex: Considerations on the Initial Response of the United Kingdom to the SARS-CoV-2 Pandemic

Evaldo Favi et al.

Summary: The initial response to COVID-19 in the UK faced criticism, especially for the high mortality rate during the first wave. This article focuses on three specific points – clinical governance, access to medical care, and non-pharmaceutical interventions, which have not been fully discussed in the UK. These considerations will likely contribute to a wider and positive discussion on public health in the context of an unprecedented crisis.

FRONTIERS IN PUBLIC HEALTH (2021)

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Article Microbiology

COVID-19-Importance for Patients on the Waiting List and after Kidney Transplantation-A Single Center Evaluation in 2020-2021

Simone C. Boedecker et al.

Summary: Dialysis patients and kidney transplant recipients are at high risk for SARS-CoV-2 infection, but immunocompromised patients can still develop antibodies. In Germany, patients on the waiting list experienced mild symptoms, while transplanted patients needed hospitalization but recovered quickly.

PATHOGENS (2021)

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Review Surgery

A systematic review and meta-analysis of COVID-19 in kidney transplant recipients: Lessons to be learned

Daan Kremer et al.

Summary: Kidney transplant recipients infected with COVID-19 have a high risk of mortality at 23% and acute kidney injury at 50%, regardless of sex, age, and comorbidities. There is a call to accelerate vaccination programs for these recipients and to consistently report key information in studies.

AMERICAN JOURNAL OF TRANSPLANTATION (2021)

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Article Urology & Nephrology

Why and how should we promote home dialysis for patients with end-stage kidney disease during and after the coronavirus 2019 disease pandemic? A French perspective

Guy Rostoker et al.

Summary: The health crisis induced by the COVID-19 pandemic has greatly impacted dialysis patients in France, with a higher incidence and mortality rate of SARS-CoV-2 infection among them compared to the general population. Home dialysis has been shown to reduce the risk of infection, but its development in France faces obstacles such as pricing policies, lack of training, and limited information. Proposed initiatives aim to provide objective information, expand home dialysis networks, and increase prices for home dialysis procedures to improve the situation.

JOURNAL OF NEPHROLOGY (2021)

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Letter Urology & Nephrology

Epidemiology and Outcomes of COVID-19 in Home Dialysis Patients Compared with In-Center Dialysis Patients

Caroline M. Hsu et al.

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2021)

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Article Transplantation

COVID-19-related mortality in kidney transplant and haemodialysis patients: a comparative, prospective registry-based study

Eric Goffin et al.

Summary: This study found that kidney transplant recipients have a higher risk of developing a more severe course of COVID-19 compared to hemodialysis patients, especially within the first year post-transplant. Therefore, specific infection mitigation strategies are needed for this group of patients.

NEPHROLOGY DIALYSIS TRANSPLANTATION (2021)

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Article Multidisciplinary Sciences

Renal allograft function in kidney transplant recipients infected with SARS-CoV 2: An academic single center experience

Skylar L. Nahi et al.

Summary: This study found that in kidney transplant recipients, severe SARS-CoV 2 infection is associated with a higher risk of acute kidney injury and a greater decline in renal allograft function at 90 days post infection, compared to mild disease.

PLOS ONE (2021)

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Article Surgery

Single-center experience of organ transplant practice during the COVID-19 epidemic

Jinghong Xu et al.

Summary: During the COVID-19 outbreak, our hospital successfully performed multiple organ transplantations with good outcomes. There were no cases of infection among patients, demonstrating the safety and feasibility of organ transplantation during the epidemic. Our experience may serve as a clinical reference for other countries dealing with COVID-19 globally.

TRANSPLANT INTERNATIONAL (2021)

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Article Surgery

COVID-19 and the Response of Transplant Centers: the Global Response with an Emphasis on the Kidney Recipient

Yorg Azzi et al.

Summary: Most elective surgeries were suspended during the pandemic, with varying responses to deceased donor transplants. There was a trend of reducing or stopping certain medications, utilizing hydroxychloroquine and/or azithromycin, and transitioning to virtual clinics. Careful donor and recipient selection, tailored immunosuppressant regimens, and telemedicine implementation were key strategies identified. The review serves as a model for managing transplant patients during future pandemics.

CURRENT TRANSPLANTATION REPORTS (2021)

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Review Medicine, General & Internal

The Management of Immunosuppression in Kidney Transplant Recipients with COVID-19 Disease: An Update and Systematic Review of the Literature

Roberta Angelico et al.

Summary: In the context of the COVID-19 pandemic, managing immunosuppressive therapy in kidney transplant recipients requires careful consideration. Adjustments to immunosuppressive therapy based on clinical conditions have been used to maintain stable renal function and balance the risks of COVID-19 complications and rejection.

MEDICINA-LITHUANIA (2021)

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Review Immunology

COVID-19 and Solid Organ Transplantation: A Review Article

Yorg Azzi et al.

Summary: Solid organ transplantation has been significantly impacted by the coronavirus pandemic, with high mortality rates reported in recipients. The pandemic led to complexities in transplantation, including new questions regarding donor and recipient screening, and decisions on continuing transplantation based on clinical implications of COVID-19 infection. The clinical outcomes of COVID-19 in transplantation may vary depending on the type of transplanted organ and recipient comorbidities.

TRANSPLANTATION (2021)

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Letter Surgery

Coronavirus disease 2019 and transplantation: A view from the inside

Andrea Gori et al.

AMERICAN JOURNAL OF TRANSPLANTATION (2020)

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Article Surgery

Early impact of COVID-19 on transplant center practices and policies in the United States

Brian J. Boyarsky et al.

AMERICAN JOURNAL OF TRANSPLANTATION (2020)

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Article Surgery

The COVID-19 outbreak in Italy: Initial implications for organ transplantation programs

Roberta Angelico et al.

AMERICAN JOURNAL OF TRANSPLANTATION (2020)

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Editorial Material Medicine, General & Internal

Critical Care Utilization for the COVID-19 Outbreak in Lombardy, Italy Early Experience and Forecast During an Emergency Response

Giacomo Grasselli et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2020)

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Editorial Material Urology & Nephrology

COVID-19 and dialysis: why we should be worried

Giuseppe Rombola et al.

JOURNAL OF NEPHROLOGY (2020)

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Review Virology

Challenges in Laboratory Diagnosis of the Novel Coronavirus SARS-CoV-2

Nadin Younes et al.

VIRUSES-BASEL (2020)

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Article Medicine, General & Internal

Offline: COVID-19 and the NHS—“a national scandal”

Richard Horton

LANCET (2020)

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Letter Gastroenterology & Hepatology

Coronaviruses and Immunosuppressed Patients: The Facts During the Third Epidemic

Lorenzo D'Antiga

LIVER TRANSPLANTATION (2020)

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Article Emergency Medicine

Emergency general surgery in Italy during the COVID-19 outbreak: first survey from the real life

Alberto Patriti et al.

WORLD JOURNAL OF EMERGENCY SURGERY (2020)

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Letter Critical Care Medicine

Kidney transplant programmes during the COVID-19 pandemic

Francesca Martino et al.

LANCET RESPIRATORY MEDICINE (2020)

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Article Cell Biology

Network-based drug repurposing for novel coronavirus 2019-nCoV/SARS-CoV-2

Yadi Zhou et al.

CELL DISCOVERY (2020)

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Editorial Material Urology & Nephrology

Minimizing the risk of COVID-19 among patients on dialysis

T. Alp Ikizler et al.

NATURE REVIEWS NEPHROLOGY (2020)

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Editorial Material Medicine, General & Internal

The Toughest Triage - Allocating Ventilators in a Pandemic

Robert D. Truog et al.

NEW ENGLAND JOURNAL OF MEDICINE (2020)

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Editorial Material Cardiac & Cardiovascular Systems

Heart transplantation management in northern Italy during COVID-19 pandemic: single-centre experience

Alessandro Fiocco et al.

ESC HEART FAILURE (2020)

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Review Urology & Nephrology

Management of Patients on Dialysis and With Kidney Transplantation During the SARS-CoV-2 (COVID-19) Pandemic in Brescia, Italy

Federico Alberici et al.

KIDNEY INTERNATIONAL REPORTS (2020)

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Article Oncology

The impact of the COVID-19 pandemic on cancer deaths due to delays in diagnosis in England, UK: a national, population-based, modelling study

Camille Maringe et al.

LANCET ONCOLOGY (2020)

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Article Hematology

COVID-19 of dialysis patients in Japan: Current status and guidance on preventive measures

Kan Kikuchi et al.

THERAPEUTIC APHERESIS AND DIALYSIS (2020)

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Editorial Material Immunology

Position Statement of Transplant Activity in the Middle East in Era of COVID-19 Pandemic

Ahmed Zidan et al.

TRANSPLANTATION (2020)

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Article Immunology

Awareness and Impact of Non-pharmaceutical Interventions During Coronavirus Disease 2019 Pandemic in Renal Transplant Recipients

Andrea Monaco et al.

TRANSPLANTATION PROCEEDINGS (2020)

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Article Radiology, Nuclear Medicine & Medical Imaging

Initial Impact of COVID-19 on Radiology Practices: An ACR/RBMA Survey

Ajay Malhotra et al.

JOURNAL OF THE AMERICAN COLLEGE OF RADIOLOGY (2020)

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Article Orthopedics

Operating room efficiency and timing during coronavirus disease 2019 outbreak in a referral orthopaedic hospital in Northern Italy

Mauro Andreata et al.

INTERNATIONAL ORTHOPAEDICS (2020)

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Review Microbiology

COVID-19 and Acute Kidney Injury: A Systematic Review and Meta-Analysis

Fabrizio Fabrizi et al.

PATHOGENS (2020)

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Review Radiology, Nuclear Medicine & Medical Imaging

Radiology imaging management in an Italian cancer center (IRST IRCCS) during the COVID-19 pandemic

Alice Rossi et al.

INSIGHTS INTO IMAGING (2020)

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Article Transplantation

COVID-19-related mortality in kidney transplant and dialysis patients: results of the ERACODA collaboration

Luuk B. Hilbrands et al.

NEPHROLOGY DIALYSIS TRANSPLANTATION (2020)

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Article Public, Environmental & Occupational Health

Deaths of Despair(ity) in Early 21st Century America: The Rise of Mortality and Racial/Ethnic Disparities

Keith P. Gennuso et al.

AMERICAN JOURNAL OF PREVENTIVE MEDICINE (2019)

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Article Immunology

Reevaluation of the Kidney Donor Risk Index

Yingchao Zhong et al.

TRANSPLANTATION (2019)

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Article Microbiology

Antiviral Potential of ERK/MAPK and PI3K/AKT/mTOR Signaling Modulation for Middle East Respiratory Syndrome Coronavirus Infection as Identified by Temporal Kinome Analysis

Jason Kindrachuk et al.

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2015)

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Outcomes of Patients Receiving a Kidney Transplant or Remaining on the Transplant Waiting List at the Epicentre of the COVID-19 Pandemic in Europe: An Observational Comparative Study

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