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Secondary Metabolites Produced by Plant Growth-Promoting Bacterial Endophytes

Journal

MICROORGANISMS
Volume 10, Issue 10, Pages -

Publisher

MDPI
DOI: 10.3390/microorganisms10102008

Keywords

therapeutic applications; secondary metabolites; plant growth promoting bacteria; endophytes; mechanisms

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There is a growing interest in using beneficial microorganisms as alternatives to chemical or plant-derived molecules for producing therapeutic agents. Bacterial endophytes, which are plant-associated microorganisms, can synthesize a wide range of secondary metabolites with unique chemical structures that have anti-microbial, antiviral, anti-cancer, and anti-inflammatory properties. The production of these bioactive compounds can also benefit the host plant.
There is an increasing interest in the use of beneficial microorganisms as alternatives to chemically synthesized or plant-derived molecules to produce therapeutic agents. Bacterial endophytes are plant-associated microorganisms that can colonize different parts of living plants without causing any diseases. Diverse endophytic bacteria possess the ability to synthesize a wide range of secondary metabolites with unique chemical structures that have been exploited for their anti-microbial, antiviral, anti-cancer, and anti-inflammatory properties. Additionally, production of these bioactive compounds can also benefit the host plant as they may play a significant role in a plant's interaction with the environment for adaptation and defense. As a result of their significant impact as curative compounds or as precursors to produce new drugs, the biotechnological possibilities of secondary metabolites derived from endophytic bacteria are immense.

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