Lysinibacillus sp. GG242 from Cattle Slurries Degrades 17β-Estradiol and Possible 2 Transformation Routes

Environmental estrogen pollution has long been a concern due to adverse effects on organisms and ecosystems. Biodegradation is a vital way to remove estrogen, a strain of Lysinibacillus sp. was isolated, numbered strain GG242. The degradation rate of 100 mg.L-1 17 beta-estradiol (E2)) > 95% in one week, and compared with extracellular enzymes, intracellular enzymes have stronger degradation ability. Strain GG242 can maintain a stable E2 degradation ability under different conditions (20-35 degrees C, pH 5-11, salinity 0-40 g.L-1). Under appropriate conditions (30 degrees C, pH 8, 1 g.L-1 NaCl), the degradation rate increased by 32.32% in one week. Based on the analysis of transformation products, inferred E2 was converted via two distinct routes. Together, this research indicates the degradation potential of strain GG242 and provides new insights into the biotransformation of E2.

Automated summary

This study identified a strain of Lysinibacillus sp. named GG242 that is capable of efficiently degrading environmental estrogen. The degradation ability of strain GG242 is not influenced by temperature, pH, or salinity. Analysis of transformation products suggests that E2 can be converted via two distinct routes.