4.7 Article

IntegralVac: A Machine Learning-Based Comprehensive Multivalent Epitope Vaccine Design Method

Related references

Note: Only part of the references are listed.
Article Immunology

A New Epitope Selection Method: Application to Design a Multi-Valent Epitope Vaccine Targeting HRAS Oncogene in Squamous Cell Carcinoma

Kush Savsani et al.

Summary: The study developed an epitope selection method for MHC targeting peptide vaccines, which was validated through experimental data. Applying clinical checkpoint filters to epitope selection proved to be an effective method for identifying top epitopes for vaccine design.

VACCINES (2022)

Article Multidisciplinary Sciences

An in silico deep learning approach to multi-epitope vaccine design: a SARS-CoV-2 case study

Zikun Yang et al.

Summary: The study introduces an in silico deep learning approach, DeepVacPred, for designing a multi-epitope vaccine against SARS-CoV-2, predicting and evaluating potential vaccine subunits, and ultimately constructing a 694aa multi-epitope vaccine that shows promise in combating the viral infection.

SCIENTIFIC REPORTS (2021)

Article Medicine, General & Internal

Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China

Chaolin Huang et al.

LANCET (2020)

Article Infectious Diseases

Epidemiological, clinical characteristics of cases of SARS-CoV-2 infection with abnormal imaging findings

Xiaoli Zhang et al.

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES (2020)

Article Multidisciplinary Sciences

Machine learning-guided discovery and design of non-hemolytic peptides

Fabien Plisson et al.

SCIENTIFIC REPORTS (2020)

Review Biology

An insight into the epitope-based peptide vaccine design strategy and studies against COVID-19

Murat Topuzogullari et al.

TURKISH JOURNAL OF BIOLOGY (2020)

Article Biochemical Research Methods

MHCSeqNet: a deep neural network model for universal MHC binding prediction

Poomarin Phloyphisut et al.

BMC BIOINFORMATICS (2019)

Review Biochemistry & Molecular Biology

Chemoresistance in Pancreatic Cancer

Siyuan Zeng et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)

Article Biochemistry & Molecular Biology

The immune epitope database (IEDB) 3.0

Randi Vita et al.

NUCLEIC ACIDS RESEARCH (2015)

Article Chemistry, Medicinal

Recent Advances in Ligand-Based Drug Design: Relevance and Utility of the Conformationally Sampled Pharmacophore Approach

Chayan Acharya et al.

CURRENT COMPUTER-AIDED DRUG DESIGN (2011)