4.7 Article

XMU-MP-1 attenuates osteoarthritis via inhibiting cartilage degradation and chondrocyte apoptosis

Related references

Note: Only part of the references are listed.
Review Cell Biology

YAP/TAZ in Bone and Cartilage Biology

Mylene Zarka et al.

Summary: YAP and TAZ are key regulators in organ growth and bone biology, responding to mechanical and cytoskeletal cues to control cell fate. They play significant roles in bone and cartilage homeostasis and their precise functions have been investigated in mouse and cellular models.

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2022)

Article Pharmacology & Pharmacy

YAP plays a protective role in T-2 toxin-induced inhibition of chondrocyte proliferation and matrix degradation

Hao-Nan Li et al.

Summary: The study found that T-2 toxin damages chondrocytes by decreasing COL2 and PCNA levels while increasing MMP13 expression; YAP plays a role in T-2 toxin-induced chondrocyte injury, activating the HIPPO signaling pathway.

TOXICON (2022)

Review Pharmacology & Pharmacy

Pharmacotherapy for knee osteoarthritis: current and emerging therapies

Peihua Cao et al.

EXPERT OPINION ON PHARMACOTHERAPY (2020)

Article Biochemistry & Molecular Biology

MiR-582-3p alleviates osteoarthritis progression by targeting YAP1

Jun He et al.

MOLECULAR IMMUNOLOGY (2020)

Article Biochemistry & Molecular Biology

Up-regulation of FOXD1 by YAP alleviates senescence and osteoarthritis

Lina Fu et al.

PLOS BIOLOGY (2019)

Review Cell Biology

NF-κB Signaling Pathways in Osteoarthritic Cartilage Destruction

Moon-Chang Choi et al.

CELLS (2019)

Review Cell Biology

Wnt signaling: a promising target for osteoarthritis therapy

Yudan Wang et al.

CELL COMMUNICATION AND SIGNALING (2019)

Review Cell Biology

The Hippo Signaling Pathway in Development and Disease

Yonggang Zheng et al.

DEVELOPMENTAL CELL (2019)

Article Genetics & Heredity

Inhibition of YAP with siRNA prevents cartilage degradation and ameliorates osteoarthritis development

Yong Gong et al.

JOURNAL OF MOLECULAR MEDICINE-JMM (2019)

Article Multidisciplinary Sciences

Reciprocal inhibition of YAP/TAZ and NF-κB regulates osteoarthritic cartilage degradation

Yujie Deng et al.

NATURE COMMUNICATIONS (2018)

Article Cell Biology

Pharmacological targeting of kinases MST1 and MST2 augments tissue repair and regeneration

Fuqin Fan et al.

SCIENCE TRANSLATIONAL MEDICINE (2016)

Review Biochemistry & Molecular Biology

Chondrocyte Apoptosis in the Pathogenesis of Osteoarthritis

Hyun Sook Hwang et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2015)

Article Rheumatology

Yes-associated protein (YAP) is a negative regulator of chondrogenesis in mesenchymal stem cells

Alexandra Karystinou et al.

ARTHRITIS RESEARCH & THERAPY (2015)

Article Medicine, General & Internal

Epidemiology and burden of osteoarthritis

Anna Litwic et al.

BRITISH MEDICAL BULLETIN (2013)

Article Cell Biology

YAP-mediated regulation of the chondrogenic phenotype in response to matrix elasticity

Weiliang Zhong et al.

JOURNAL OF MOLECULAR HISTOLOGY (2013)

Article Biochemistry & Molecular Biology

Hippo signaling: A hub of growth control, tumor suppression and pluripotency maintenance

Mengxin Yin et al.

JOURNAL OF GENETICS AND GENOMICS (2011)

Review Cell Biology

Hippo signaling in organ size control

Duojia Pan

GENES & DEVELOPMENT (2007)

Article Rheumatology

Apoptosis in normal and osteoarthritic human articular cartilage

F Héraud et al.

ANNALS OF THE RHEUMATIC DISEASES (2000)