4.7 Review

Regenerative medicine technologies applied to transplant medicine. An update

Journal

Publisher

FRONTIERS MEDIA SA
DOI: 10.3389/fbioe.2022.1015628

Keywords

regenerative medicine; transplant medicine; cell therapeutics; organ regeneration; tissue engineering

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Regenerative medicine is a field that is changing the practice of transplant medicine by developing methods to regenerate or replace damaged organs and tissues. This review highlights advancements in regenerative medicine specifically relating to transplant medicine, focusing on tools and techniques designed for different organs such as the kidney, heart, liver, and lungs.
Regenerative medicine (RM) is changing how we think and practice transplant medicine. In regenerative medicine, the aim is to develop and employ methods to regenerate, restore or replace damaged/diseased tissues or organs. Regenerative medicine investigates using tools such as novel technologies or techniques, extracellular vesicles, cell-based therapies, and tissue-engineered constructs to design effective patient-specific treatments. This review illustrates current advancements in regenerative medicine that may pertain to transplant medicine. We highlight progress made and various tools designed and employed specifically for each tissue or organ, such as the kidney, heart, liver, lung, vasculature, gastrointestinal tract, and pancreas. By combing both fields of transplant and regenerative medicine, we can harbor a successful collaboration that would be beneficial and efficacious for the repair and design of de novo engineered whole organs for transplantations.

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