4.7 Review

Gαi protein subunit: A step toward understanding its non-canonical mechanisms

Related references

Note: Only part of the references are listed.
Article Multidisciplinary Sciences

Stearic acid blunts growth-factor signaling via oleoylation of GNAI proteins

Hana Nuskova et al.

Summary: This study reveals that exposure of cells to different fatty acids affects the acylation of GNAI proteins, altering their function and EGFR pathway activation, thus linking metabolism to signaling pathways.

NATURE COMMUNICATIONS (2021)

Review Cell Biology

The cortical force-generating machinery: how cortical spindle-pulling forces are generated

Tomomi Kiyomitsu

CURRENT OPINION IN CELL BIOLOGY (2019)

Article Multidisciplinary Sciences

Evolutionary modification of AGS protein contributes to formation of micromeres in sea urchins

Jessica Poon et al.

NATURE COMMUNICATIONS (2019)

Article Biochemistry & Molecular Biology

Activated heterotrimeric G protein i subunits inhibit Rap-dependent cell adhesion and promote cell migration

Jesi Y. To et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2018)

Article Biochemistry & Molecular Biology

c-Src activity is differentially required by cancer cell motility modes

Jeremy S. Logue et al.

ONCOGENE (2018)

Article Multidisciplinary Sciences

Antidepression action of BDNF requires and is mimicked by Gαi1/3 expression in the hippocampus

John Marshall et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)

Article Medicine, Research & Experimental

Gαi1 and Gαi3mediate VEGF-induced VEGFR2 endocytosis, signaling and angiogenesis

Jian Sun et al.

THERANOSTICS (2018)

Article Multidisciplinary Sciences

Defining stem cell dynamics and migration during wound healing in mouse skin epidermis

Mariaceleste Aragona et al.

NATURE COMMUNICATIONS (2017)

Article Biochemistry & Molecular Biology

Distinct effects on the dendritic arbor occur by microbead versus bath administration of brain-derived neurotrophic factor

Kate M. O'Neill et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2017)

Review Biochemistry & Molecular Biology

Regulation of mitotic spindle orientation: an integrated view

Florencia di Pietro et al.

EMBO REPORTS (2016)

Article Developmental Biology

Expression profiles of the Gα subunits during Xenopus tropicalis embryonic development

Jaime Fuentealba et al.

GENE EXPRESSION PATTERNS (2016)

Article Biochemistry & Molecular Biology

Dynamic regulation of neutrophil polarity and migration by the heterotrimeric G protein subunits Gαi-GTP and Gβγ

Chinmay R. Surve et al.

SCIENCE SIGNALING (2016)

Article Biochemistry & Molecular Biology

Dynamic regulation of neutrophil polarity and migration by the heterotrimeric G protein subunits Gαi-GTP and Gβγ

Chinmay R. Surve et al.

SCIENCE SIGNALING (2016)

Article Biochemistry & Molecular Biology

Evolutionary hierarchy of vertebrate-like heterotrimeric G protein families

Arunkumar Krishnan et al.

MOLECULAR PHYLOGENETICS AND EVOLUTION (2015)

Article Immunology

Defective Macrophage Migration in Gαi2- but Not Gαi3-Deficient Mice

Kristina Wiege et al.

JOURNAL OF IMMUNOLOGY (2012)

Article Multidisciplinary Sciences

Distinct contribution of stem and progenitor cells to epidermal maintenance

Guilhem Mascre et al.

NATURE (2012)

Article Multidisciplinary Sciences

Development of the mammalian axial skeleton requires signaling through the Gαi subfamily of heterotrimeric G proteins

Nicholas W. Plummer et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

Article Oncology

Clinical Implications for Girdin Protein Expression in Breast Cancer

Yun Ling et al.

CANCER INVESTIGATION (2011)

Article Biochemistry & Molecular Biology

Expression of GIV/Girdin, a metastasis-related protein, predicts patient survival in colon cancer

Mikel Garcia-Marcos et al.

FASEB JOURNAL (2011)

Article Biochemistry & Molecular Biology

Ric-8 Proteins Are Molecular Chaperones That Direct Nascent G Protein α Subunit Membrane Association

Meital Gabay et al.

SCIENCE SIGNALING (2011)

Review Cell Biology

Rho protein crosstalk: another social network?

Christophe Guilluy et al.

TRENDS IN CELL BIOLOGY (2011)

Review Cell Biology

Asymmetric cell division: recent developments and their implications for tumour biology

Juergen A. Knoblich

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2010)

Article Cell Biology

Polarity proteins regulate mammalian cell-cell junctions and cancer pathogenesis

Michael E. Feigin et al.

CURRENT OPINION IN CELL BIOLOGY (2009)

Article Multidisciplinary Sciences

GIV is a nonreceptor GEF for Gαi with a unique motif that regulates Akt signaling

Mikel Garcia-Marcos et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

Article Biochemistry & Molecular Biology

Gαi1 and Gαi3 Are Required for Epidermal Growth Factor-Mediated Activation of the Akt-mTORC1 Pathway

Cong Cao et al.

SCIENCE SIGNALING (2009)

Article Biochemistry & Molecular Biology

Lysophosphatidic acid receptor 2 and Gi/Src pathway mediate cell motility through cyclooxygenase 2 expression in CAOV-3 ovarian cancer cells

Kang Jin Jeong et al.

EXPERIMENTAL AND MOLECULAR MEDICINE (2008)

Article Cell Biology

Activation of Gαi3 triggers cell migration via regulation of GIV

Pradipta Ghosh et al.

JOURNAL OF CELL BIOLOGY (2008)

Article Hematology

Gαi2 is required for chemokine-induced neutrophil arrest

Alexander Zarbock et al.

BLOOD (2007)

Article Cell Biology

Heterotrimeric G protein signaling functions with dynein to promote spindle positioning in C. elegans

Claudia Couwenbergs et al.

JOURNAL OF CELL BIOLOGY (2007)

Review Biochemistry & Molecular Biology

Assembly and trafficking of heterotrimeric G proteins

Yannick Marrari et al.

BIOCHEMISTRY (2007)

Article Endocrinology & Metabolism

Direct interactions with Gαi and Gβγ mediate nongenomic signaling by estrogen receptor α

Premlata Kumar et al.

MOLECULAR ENDOCRINOLOGY (2007)

Review Biochemistry & Molecular Biology

G protein regulation of MAPK networks

Z. G. Goldsmith et al.

ONCOGENE (2007)

Article Biochemistry & Molecular Biology

Inhibition of Gαi2 activation by Gαi3 in CXCR3-mediated signaling

Brian D. Thompson et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

Article Multidisciplinary Sciences

Gαi2-mediated signaling events in the endotheliurn are involved in controlling leukocyte extravasation

Ralph S. Pero et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)

Article Multidisciplinary Sciences

An obligatory requirement for the heterotrimeric G protein Gi3 in the antiautophagic action of insulin in the liver

Antje Gohla et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)

Review Biochemistry & Molecular Biology

Expansion of signal transduction by G proteins - The second 15 years or so: From 3 to 16 alpha subunits plus beta gamma dimers

Lutz Birnbaumer

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2007)

Review Pharmacology & Pharmacy

Mechanistic pathways and biological roles for receptor-independent activators of G-protein signaling

Joe B. Blumer et al.

PHARMACOLOGY & THERAPEUTICS (2007)

Article Biochemistry & Molecular Biology

The Gα13-Rho signaling axis is required for SDF-1-induced migration through CXCR4

Wenfu Tan et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2006)

Article Multidisciplinary Sciences

Dual roles for the trimeric G protein Go in asymmetric cell division in Drosophila

VL Katanaev et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

Review Cell Biology

Heterotrimeric G proteins and regulation of size asymmetry during cell division

Y Bellaiche et al.

CURRENT OPINION IN CELL BIOLOGY (2005)

Review Biochemistry & Molecular Biology

The GAPs, GEFs, and GDIs of heterotrimeric G-protein alpha subunits

David P. Siderovski et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES (2005)

Article Biochemistry & Molecular Biology

Trimeric G protein-dependent frizzled signaling in Drosophila

VL Katanaev et al.

Review Cell Biology

G proteins in development

CC Malbon

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2005)

Review Cell Biology

Chemotaxis: Signalling the way forward

PJM Van Haastert et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2004)

Article Biochemistry & Molecular Biology

Regulation of CXC chemokine receptor 4-mediated migration by the tec family tyrosine kinase ITK

AM Fischer et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2004)

Review Biochemistry & Molecular Biology

Return of the GDI: The GoLoco motif in cell division

FS Willard et al.

ANNUAL REVIEW OF BIOCHEMISTRY (2004)

Review Biochemistry & Molecular Biology

Not so strange bedfellows: G-protein-coupled receptors and Src family kinases

DK Luttrell et al.

ONCOGENE (2004)

Article Biochemistry & Molecular Biology

Involvement of phosphoinositide 3-kinase γ, Rac, and PAK signaling in chemokine-induced macrophage migration

C Weiss-Haljiti et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2004)

Article Biochemistry & Molecular Biology

Gβγ mediates the interplay between tubulin dimers and microtubules in the modulation of Gq signaling

JS Popova et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2003)

Article Biochemistry & Molecular Biology

Serotonin promotes Go-dependent neuronal migration in Caenorhabditis elegans

KS Kindt et al.

CURRENT BIOLOGY (2002)

Review Cell Biology

Seven-transmembrane receptors

KL Pierce et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2002)

Article Medicine, Research & Experimental

Receptor-independent activators of heterotrimeric G-proteins

MJ Cismowski et al.

LIFE SCIENCES (2001)

Article Biochemistry & Molecular Biology

Regulation of G proteins by covalent modification

CA Chen et al.

ONCOGENE (2001)

Article Biochemistry & Molecular Biology

Heterotrimeric G-protein βγ-dimers in growth and differentiation

WF Schwindinger et al.

ONCOGENE (2001)

Article Biochemistry & Molecular Biology

Regulation of the Golgi structure by the α subunits of heterotrimeric G proteins

T Yamaguchi et al.

FEBS LETTERS (2000)