4.7 Article

Multiparametric MRI to quantify disease and treatment response in mice with myeloproliferative neoplasms

Related references

Note: Only part of the references are listed.
Review Hematology

A provider's guide to primary myelofibrosis: pathophysiology, diagnosis, and management

Benjamin Garmezy et al.

Summary: Treatment options for primary myelofibrosis are limited, but diagnosis can often be established through appropriate clinical history, examination, laboratory evaluation, and bone marrow biopsy. Recent studies have characterized prognostic factors and driver mutations better, leading to the development of treatment strategies based on risk factors and clinical phenotype.

BLOOD REVIEWS (2021)

Review Biochemistry & Molecular Biology

Inflammatory Microenvironment and Specific T Cells in Myeloproliferative Neoplasms: Immunopathogenesis and Novel Immunotherapies

Vincenzo Nasillo et al.

Summary: The immune dysregulation plays a significant role in the pathogenesis and development of MPNs, with detrimental cytokine milieu, expansion and altered functions of immune cells. MPNs can evade T cell immune surveillance through the PD-1/PD-L1 axis.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

Article Multidisciplinary Sciences

Diffusion-weighted magnetic resonance imaging for the assessment of liver fibrosis in chronic viral hepatitis

Phunchai Charatcharoenwitthaya et al.

Summary: This study confirmed the diagnostic accuracy of diffusion-weighted magnetic resonance imaging for cirrhosis in patients with chronic viral hepatitis, proposing a sequential approach combining normalized liver ADC measurement with the Fibrosis-4 index to reduce the need for liver biopsies.

PLOS ONE (2021)

Article Endocrinology & Metabolism

Preclinical models for investigating how bone marrow adipocytes influence bone and hematopoietic cellularity

Ziru Li et al.

Summary: Laboratory mice are a valuable preclinical model for studying common human diseases related to osteopenia or hematopoietic disorders. However, factors such as species, age, sex, skeletal site, and treatment protocol should all be taken into consideration when choosing the appropriate model for future studies.

BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM (2021)

Review Immunology

Inflammatory Pathophysiology as a Contributor to Myeloproliferative Neoplasms

Daniel Arthur Corpuz Fisher et al.

Summary: Myeloid neoplasms such as AML, MPNs, and MDS involve clonal dominance and remodeling of bone marrow niche leading to malignant hematopoiesis. Inflammatory signaling hyperactivation and cytokine overproduction play critical roles, with cytokines like TNF potentially contributing to malignant clonal dominance. Targeting cytokine-mediated signaling may be a promising therapeutic strategy.

FRONTIERS IN IMMUNOLOGY (2021)

Review Hematology

Management of myelofibrosis after ruxolitinib failure

Claire N. Harrison et al.

ANNALS OF HEMATOLOGY (2020)

Review Oncology

Murine Models of Myelofibrosis

Sebastien Jacquelin et al.

CANCERS (2020)

Article Radiology, Nuclear Medicine & Medical Imaging

Proton density fat fraction MRI of vertebral bone marrow: Accuracy, repeatability, and reproducibility among readers, field strengths, and imaging platforms

Frederic Carsten Schmeel et al.

JOURNAL OF MAGNETIC RESONANCE IMAGING (2019)

Review Oncology

Myelofibrosis in 2019: moving beyond JAK2 inhibition

Michael Schieber et al.

BLOOD CANCER JOURNAL (2019)

Article Radiology, Nuclear Medicine & Medical Imaging

Short-Term Environmental Conditioning Enhances Tumorigenic Potential of Triple-Negative Breast Cancer Cells

Samantha S. Eckley et al.

TOMOGRAPHY (2019)

Review Biochemistry & Molecular Biology

Understanding Splenomegaly in Myelofibrosis: Association with Molecular Pathogenesis

Moo-Kon Song et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)

Review Medicine, General & Internal

Clinical implications of bone marrow adiposity

A. G. Veldhuis-Vlug et al.

JOURNAL OF INTERNAL MEDICINE (2018)

Article Physiology

Multiparametric MRI detects longitudinal evolution of folic acid-induced nephropathy in mice

Kai Jiang et al.

AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2018)

Review Hematology

Bone marrow evaluation for diagnosis and monitoring of acute myeloid leukemia

Mary-Elizabeth Percival et al.

BLOOD REVIEWS (2017)

Letter Oncology

In vivo magnetic resonance imaging of a mouse model of myelofibrosis

S. Matsuura et al.

BLOOD CANCER JOURNAL (2016)

Article Radiology, Nuclear Medicine & Medical Imaging

A Pilot Study of Quantitative MRI Parametric Response Mapping of Bone Marrow Fat for Treatment Assessment in Myelofibrosis

Gary D. Luker et al.

TOMOGRAPHY (2016)

Article Radiology, Nuclear Medicine & Medical Imaging

Magnetization Transfer Ratio A Potential Biomarker for the Assessment of Postradiation Fibrosis in Patients With Rectal Cancer

Milou H. Martens et al.

INVESTIGATIVE RADIOLOGY (2014)

Article Radiology, Nuclear Medicine & Medical Imaging

Diffusion-weighted MR Imaging for Characterizing Musculoskeletal Lesions

Ty K. Subhawong et al.

RADIOGRAPHICS (2014)

Article Mathematical & Computational Biology

Fast parallel image registration on CPU and GPU for diagnostic classification of Alzheimer's disease

Denis P. Shamonin et al.

FRONTIERS IN NEUROINFORMATICS (2014)

Review Biochemistry & Molecular Biology

The role of cytokines in the initiation and progression of myelofibrosis

Hans C. Hasselbalch

CYTOKINE & GROWTH FACTOR REVIEWS (2013)

Article Medicine, General & Internal

Somatic Mutations of Calreticulin in Myeloproliferative Neoplasms

Thorsten Klampfl et al.

NEW ENGLAND JOURNAL OF MEDICINE (2013)

Article Medicine, General & Internal

A Double-Blind, Placebo-Controlled Trial of Ruxolitinib for Myelofibrosis

Srdan Verstovsek et al.

NEW ENGLAND JOURNAL OF MEDICINE (2012)

Article Medicine, General & Internal

JAK Inhibition with Ruxolitinib versus Best Available Therapy for Myelofibrosis

Claire Harrison et al.

NEW ENGLAND JOURNAL OF MEDICINE (2012)

Article Radiology, Nuclear Medicine & Medical Imaging

Bone Marrow Signal Alteration in the Spine and Sacrum

Suzanne S. Long et al.

AMERICAN JOURNAL OF ROENTGENOLOGY (2010)

Article Computer Science, Interdisciplinary Applications

elastix: A Toolbox for Intensity-Based Medical Image Registration

Stefan Klein et al.

IEEE TRANSACTIONS ON MEDICAL IMAGING (2010)

Article Radiology, Nuclear Medicine & Medical Imaging

Quantification of Liver Fat with Magnetic Resonance Imaging

Scott B. Reeder et al.

MAGNETIC RESONANCE IMAGING CLINICS OF NORTH AMERICA (2010)

Article Radiology, Nuclear Medicine & Medical Imaging

Robust Water/Fat Separation in the Presence of Large Field Inhomogeneities Using a Graph Cut Algorithm

Diego Hernando et al.

MAGNETIC RESONANCE IN MEDICINE (2010)

Review Radiology, Nuclear Medicine & Medical Imaging

MR Imaging Insights into Skeletal Maturation: What Is Normal?

Tal Laor et al.

RADIOLOGY (2009)

Review Hematology

Flow cytometric immunophenotyping for hematologic neoplasms

Fiona E. Craig et al.

BLOOD (2008)

Article Endocrinology & Metabolism

MRI-measured bone marrow adipose tissue is inversely related to DXA-measured bone mineral in Caucasian women

W. Shen et al.

OSTEOPOROSIS INTERNATIONAL (2007)

Article Medicine, General & Internal

MPLW515L is anovel somatic activating mutation in myelofibrosis with myeloid metaplasia

Yana Pikman et al.

PLOS MEDICINE (2006)

Article Medicine, General & Internal

A gain-of-function mutation of JAK2 in myeloproliferative disorders

R Kralovics et al.

NEW ENGLAND JOURNAL OF MEDICINE (2005)

Article Oncology

CXCR4 regulates growth of both primary and metastatic breast cancer

MCP Smith et al.

CANCER RESEARCH (2004)

Article Radiology, Nuclear Medicine & Medical Imaging

Normal lumbar vertebrae: Anatomic, age, and sex variance in subjects at proton MR spectroscopy - Initial experience

D Schellinger et al.

RADIOLOGY (2000)

Article Multidisciplinary Sciences

Combined effect of tumor necrosis factor-related apoptosis-inducing ligand and ionizing radiation in breast cancer therapy

AM Chinnaiyan et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)