4.6 Editorial Material

Non-invasive monitoring of autophagy

Journal

NATURE BIOMEDICAL ENGINEERING
Volume 6, Issue 9, Pages 1015-1016

Publisher

NATURE PORTFOLIO
DOI: 10.1038/s41551-022-00943-w

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The flux of autophagosomes in heart tissue can be detected in live mice using fluorescent peptides cleavable by lysosomal cathepsins, which are decorated on intravenously injected iron oxide nanoparticles with fluorescence and magnetic resonance properties.
The flux of autophagosomes in heart tissue can be detected in live mice via the fluorescence and magnetic resonance properties of intravenously injected iron oxide nanoparticles decorated with fluorescent peptides cleavable by lysosomal cathepsins.

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