Feasibility of At-Home Virological and Serological Testing for SARS-CoV-2 in Children

Article Pediatrics

Test-to-Stay After Exposure to SARS-CoV-2 in K-12 Schools

Melissa M. Campbell et al.

Summary: This study evaluated the safety and effectiveness of a "test-to-stay" program for unvaccinated students and staff who had unmasked contact with individuals confirmed to have SARS-CoV-2 infection in schools. Instead of quarantine, asymptomatic contacts were offered serial testing. The results showed that this strategy is a safe alternative to quarantine, reducing isolation time without increasing the risk of transmission.

PEDIATRICS (2022)

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Article Public, Environmental & Occupational Health

At-home testing to mitigate community transmission of SARS-CoV-2: protocol for a public health intervention with a nested prospective cohort study

Emily J. Ciccone et al.

Summary: The study aims to evaluate the impact of at-home self-testing on SARS-CoV-2 community transmission through an ecological study and behavioral aspects of testing research. This is the first large-scale public health intervention project in the United States, designed to provide insights into innovative methods to mitigate viral transmission and advance the science of public health communications and community engagement.

BMC PUBLIC HEALTH (2021)

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News Item Medicine, General & Internal

COVID-19 Testing Moves Out of the Clinic and Into the Home

Rita Rubin

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2021)

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Article Pediatrics

Prevalence of SARS-CoV-2 Infection in Children and Their Parents in Southwest Germany

Burkhard Toenshoff et al.

Summary: A study conducted in southwest Germany showed that the rate of SARS-CoV-2 infections was low among children aged 1 to 10, suggesting that they are unlikely to have significantly contributed to the pandemic. Large-scale testing provides a basis for informed political decision-making during a pandemic.

JAMA PEDIATRICS (2021)

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Article Multidisciplinary Sciences

A cross-sectional investigation of SARS-CoV-2 seroprevalence and associated risk factors in children and adolescents in the United States

Rebecca E. Levorson et al.

Summary: Pediatric SARS-CoV-2 seropositivity rates were found to be higher than previously reported in a major metropolitan region of the US. Even though a majority of the seropositive children were asymptomatic, a significant burden of COVID-19 infection was found in this population.

PLOS ONE (2021)

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Article Public, Environmental & Occupational Health

Estimated SARS-CoV-2 Seroprevalence Among Persons Aged

Charlotte V. Hobbs et al.

MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT (2021)

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Article Public, Environmental & Occupational Health

Evaluation of a Test to Stay Strategy in Transitional Kindergarten Through Grade 12 Schools — Los Angeles County, California, August 16–October 31, 2021

Kimberly Harris-McCoy et al.

MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT (2021)

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Article Medicine, General & Internal

Seroprevalence of SARS-CoV-2 Antibodies Among Children in School and Day Care in Montreal, Canada

Kate Zinszer et al.

Summary: This study aimed to estimate the seroprevalence of SARS-CoV-2 antibodies in children and teenagers in 4 neighborhoods of Montreal, Canada. The results indicate a higher level of transmission in children compared to what was detected by RT-PCR, with most cases experiencing mild or no symptoms.

JAMA NETWORK OPEN (2021)

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Article Pediatrics

SARS-CoV-2 Infection Dynamics in Children and Household Contacts in a Slum in Rio de Janeiro

Pamella Lugon et al.

Summary: The study found that in this impoverished urban area, children are not the source of SARS-CoV-2 infection and mostly acquire the virus from adults. The findings suggest that in settings like this, schools and child care facilities could potentially be reopened safely if proper COVID-19 mitigation measures are in place and staff are adequately immunized.

PEDIATRICS (2021)

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Article Medicine, General & Internal

Clustering and longitudinal change in SARS-CoV-2 seroprevalence in school children in the canton of Zurich, Switzerland: prospective cohort study of 55 schools

Agne Ulyte et al.

Summary: This study examined longitudinal changes in SARS-CoV-2 seroprevalence and clustering of seropositive children in schools in Zurich, Switzerland from June to November 2020. The overall seroprevalence increased during this period, with varying rates across districts. The clustering of seropositive children was observed in only a few classes, indicating that with schools open and preventive measures in place, transmission of SARS-CoV-2 among children was limited despite community transmission.

BMJ-BRITISH MEDICAL JOURNAL (2021)

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Article Infectious Diseases

Duration of SARS-CoV-2 sero-positivity in a large longitudinal sero-surveillance cohort: the COVID-19 Community Research Partnership

David M. Herrington et al.

Summary: This study found that approximately 50% of participants with SARS-CoV-2 infection but minimal or no symptoms experienced antibody reversion within 30 days of their initial positive test. IgM reverted more quickly than IgG. Overall, the duration of antibody response was short.

BMC INFECTIOUS DISEASES (2021)

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Article Pediatrics

Seroprevalence of SARS-CoV-2 antibodies in children: a prospective multicentre cohort study

Thomas Waterfield et al.

Summary: This study found that children had similar antibody responses to SARS-CoV-2 regardless of age, with fatigue, gastrointestinal symptoms, and changes in sense of smell or taste being the symptoms most strongly associated with SARS-CoV-2 antibody positivity.

ARCHIVES OF DISEASE IN CHILDHOOD (2021)

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Article Endocrinology & Metabolism

Anxiety associated with self monitoring of capillary blood glucose

Amy Shlomowitz et al.

BRITISH JOURNAL OF DIABETES AND VASCULAR DISEASE (2014)

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Article Gastroenterology & Hepatology

Feasibility of a finger prick-based self-testing kit in first- and second-degree relatives of children with coeliac disease

Judith Pichler et al.

WORLD JOURNAL OF GASTROENTEROLOGY (2011)

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Feasibility of At-Home Virological and Serological Testing for SARS-CoV-2 in Children

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