Journal
FRONTIERS IN ONCOLOGY
Volume 12, Issue -, Pages -Publisher
FRONTIERS MEDIA SA
DOI: 10.3389/fonc.2022.1002530
Keywords
consensus statement; rectal cancer; rectum; low-anterior resection; abdominoperineal resection; local excision; circumferential resection margin; total mesorectal excision
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This study describes the method of personalizing international guidelines for rectal cancer management to the Indian context. The expert group reached a consensus through literature review and expert opinions, and classified the consensus statements as strong or weak. Disseminating these research findings to a wider medical community is of great importance.
IntroductionThere are standard treatment guidelines for the surgical management of rectal cancer, that are advocated by recognized physician societies. But, owing to disparities in access and affordability of various treatment options, there remains an unmet need for personalizing these international guidelines to Indian settings. MethodsClinical Robotic Surgery Association (CRSA) set up the Indian rectal cancer expert group, with a pre-defined selection criterion and comprised of the leading surgical oncologists and gastrointestinal surgeons managing rectal cancer in India. Following the constitution of the expert Group, members identified three areas of focus and 12 clinical questions. A thorough review of the literature was performed, and the evidence was graded as per the levels of evidence by Oxford Centre for Evidence-Based Medicine. The consensus was built using the modified Delphi methodology of consensus development. A consensus statement was accepted only if >= 75% of the experts were in agreement. ResultsUsing the results of the review of the literature and experts' opinions; the expert group members drafted and agreed on the final consensus statements, and these were classified as strong or weak, based on the GRADE framework. ConclusionThe expert group adapted international guidelines for the surgical management of localized and locally advanced rectal cancer to Indian settings. It will be vital to disseminate these to the wider surgical oncologists and gastrointestinal surgeons' community in India.
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