4.7 Article

Surgical Treatment and Complications of Deep-Seated Nodular Plexiform Neurofibromas Associated with Neurofibromatosis Type 1

Related references

Note: Only part of the references are listed.
Article Clinical Neurology

Diffusion-Weighted Magnetic Resonance Imaging Improves the Accuracy of Differentiation of Benign from Malignant Peripheral Nerve Sheath Tumors

Hiroshi Koike et al.

Summary: There are significant differences between MPNST and pNF in terms of tumor size, peripheral enhancement pattern, perilesional edema-like zone, and intratumoral cystic change. The ADC values were significantly lower in MPNST compared to pNF, and setting a cutoff value of mean ADC at 1.85 x 10(-)(3) mm(2)/s provided sensitivity of 80% and specificity of 74%. Adding ADC evaluation to standard MRI evaluation improved the diagnostic accuracy.

WORLD NEUROSURGERY (2022)

Article Health Care Sciences & Services

The Number of Surgical Interventions and Specialists Involved in the Management of Patients with Neurofibromatosis Type I: A 25-Year Analysis

Chih-Kai Hsu et al.

Summary: This study presents a 25-year experience of utilizing a comprehensive multidisciplinary team-based surgical approach for treating NF-1 patients at a single institution. The study highlights the potential benefits of such an approach in providing comprehensive individualized care, reducing the number of surgical interventions and involvement of specialists.

JOURNAL OF PERSONALIZED MEDICINE (2022)

Article Oncology

Limitations and benefits of FDG-PET/CT in NF1 patients with nerve sheath tumors: A cross-sectional/longitudinal study

Yoshihiro Nishida et al.

Summary: This study aimed to confirm the usefulness of PET/CT in differentiating benignity/malignancy of neurogenic tumors in NF1 patients. It found that MPNST had significantly higher SUVmax compared to pNF, providing a certain sensitivity and specificity for distinguishing the two.

CANCER SCIENCE (2021)

Article Medicine, General & Internal

Characteristics, treatment patterns, healthcare resource use, and costs among pediatric patients diagnosed with neurofibromatosis type 1 and plexiform neurofibromas: a retrospective database analysis of a medicaid population

Xiaoqin Yang et al.

Summary: This study found that many pediatric patients newly diagnosed with NF1 and PN were initially treated with supportive care only, highlighting a substantial unmet medical need. Additionally, the study also highlighted the considerable economic burden among patients with NF1 and PN.

CURRENT MEDICAL RESEARCH AND OPINION (2021)

Article Surgery

Hemorrhagic Complication in Surgical Resection for Massive Plexiform Neurofibroma in Body Trunk: The Flow-Void Sign as a Predictor and Preoperative Embolization as Prevention

Kenkichi Michimoto et al.

Summary: This study found that the flow-void sign on MRI can be the only predictive factor of perioperative hemorrhagic events (PHE) in surgical resection for massive plexiform neurofibromas (PNs) in the body trunk. Preoperative transcatheter arterial embolization (TAE) can reduce the PHE risk for PNs with a flow-void sign.

WORLD JOURNAL OF SURGERY (2021)

Article Multidisciplinary Sciences

Establishment of in-hospital clinical network for patients with neurofibromatosis type 1 in Nagoya University Hospital

Yoshihiro Nishida et al.

Summary: Neurofibromatosis type 1 (NF1) is a genetic multisystem disorder that requires multidisciplinary treatment. A specialized in-hospital medical care network has been established in Japan for NF1 patients, leading to increased patient numbers especially among those who had their first visit at a younger age.

SCIENTIFIC REPORTS (2021)

Article Clinical Neurology

Safe marginal resection of atypical neurofibromas in neurofibromatosis type 1

Charlie N. Nelson et al.

JOURNAL OF NEUROSURGERY (2020)

Article Clinical Neurology

The Risk of Peripheral Nerve Tumor Biopsy in Suspected Benign Etiologies

Roberto J. Perez-Roman et al.

NEUROSURGERY (2020)

Article Medicine, General & Internal

Activity of Selumetinib in Neurofibromatosis Type 1-Related Plexiform Neurofibromas

Eva Dombi et al.

NEW ENGLAND JOURNAL OF MEDICINE (2016)

Article Genetics & Heredity

Growth behavior of plexiform neurofibromas after surgery

Rosa Nguyen et al.

GENETICS IN MEDICINE (2013)

Review Pathology

Pathogenesis of Plexiform Neurofibroma: Tumor-Stromal/Hematopoietic Interactions in Tumor Progression

Karl Staser et al.

ANNUAL REVIEW OF PATHOLOGY: MECHANISMS OF DISEASE, VOL 7 (2012)

Article Surgery

Use of the LigaSure™ vessel sealing system in neurofibroma excision to control postoperative bleeding

Eri Konno et al.

JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY (2012)

Article Genetics & Heredity

Growth dynamics of plexiform neurofibromas: a retrospective cohort study of 201 patients with neurofibromatosis 1

Rosa Nguyen et al.

ORPHANET JOURNAL OF RARE DISEASES (2012)

Article Orthopedics

Resection of Plexiform Neurofibromas in Children With Neurofibromatosis Type 1

Federico Canavese et al.

JOURNAL OF PEDIATRIC ORTHOPAEDICS (2011)

Article Radiology, Nuclear Medicine & Medical Imaging

MRI Features in the Differentiation of Malignant Peripheral Nerve Sheath Tumors and Neurofibromas

Junji Wasa et al.

AMERICAN JOURNAL OF ROENTGENOLOGY (2010)

Article Clinical Neurology

Operative outcomes of 546 Louisiana State University Health Sciences Center peripheral nerve tumors

DH Kim et al.

NEUROSURGERY CLINICS OF NORTH AMERICA (2004)